{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T02:48:07Z","timestamp":1792723687335,"version":"4.5.0"},"reference-count":28,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,12,4]]},"abstract":"<jats:p>Although human infections of <jats:italic>Plasmodium knowlesi<\/jats:italic> have been found throughout Southeast Asia, most cases originated from Malaysian Borneo. In Thailand, <jats:italic>P. knowlesi<\/jats:italic> malaria was considered extremely rare. However, during October 2017\u2013September 2018, there was a surge in the number of reported <jats:italic>P. knowlesi<\/jats:italic> cases. Here, a series of six cases of <jats:italic>P. knowlesi<\/jats:italic> malaria found during this period in Songkhla and Narathiwat provinces of southern Thailand are presented. All cases were confirmed by polymerase chain reaction. The unprecedented case number in the affected area is a warning sign of an increasing <jats:italic>P. knowlesi<\/jats:italic> burden in the south of Thailand.<\/jats:p>","DOI":"10.4269\/ajtmh.19-0063","type":"journal-article","created":{"date-parts":[[2019,10,8]],"date-time":"2019-10-08T07:00:33Z","timestamp":1570518033000},"page":"1397-1401","source":"Crossref","is-referenced-by-count":36,"title":["Case Report: Case Series of Human Plasmodium knowlesi Infection on the Southern Border of Thailand"],"prefix":"10.4269","volume":"101","author":[{"given":"Sutharinee","family":"Ngernna","sequence":"first","affiliation":[{"name":"Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nattawan","family":"Rachaphaew","sequence":"additional","affiliation":[{"name":"Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suwich","family":"Thammapalo","sequence":"additional","affiliation":[{"name":"Office of Disease Prevention and Control Region 12 Songkhla, Department of Disease Control, Ministry of Public Health, Songkhla, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pathomporn","family":"Prikchoo","sequence":"additional","affiliation":[{"name":"Office of Disease Prevention and Control Region 12 Songkhla, Department of Disease Control, Ministry of Public Health, Songkhla, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Opart","family":"Kaewnah","sequence":"additional","affiliation":[{"name":"Vector-Borne Diseases Control Center 12.2, Songkhla, Department of Disease Control, Ministry of Public Health, Songkhla, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khajohnpong","family":"Manopwisedjaroen","sequence":"additional","affiliation":[{"name":"Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanit","family":"Phumchuea","sequence":"additional","affiliation":[{"name":"Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chayanut","family":"Suansomjit","sequence":"additional","affiliation":[{"name":"Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanlapa","family":"Roobsoong","sequence":"additional","affiliation":[{"name":"Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jetsumon","family":"Sattabongkot","sequence":"additional","affiliation":[{"name":"Mahidol Vivax Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liwang","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wang","family":"Nguitragool","sequence":"additional","affiliation":[{"name":"Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Clin Infect Dis","first-page":"172","article-title":"Plasmodium knowlesi: the fifth human malaria parasite","volume":"46","author":"White","year":"2008"},{"key":"b2","series-title":"Clin Microbiol Rev","first-page":"165","article-title":"Human infections and detection of Plasmodium knowlesi","volume":"26","author":"Singh","year":"2013"},{"key":"b3","series-title":"Plasmodium knowlesi Current Status and the Request for Review by an Evidence Review Group Committee","author":"Abeyasinghe","year":"2016"},{"key":"b4","series-title":"Emerg Infect Dis","first-page":"1232","article-title":"Co-infections of Plasmodium knowlesi, P. falciparum, and P. vivax among humans and Anopheles dirus mosquitoes, southern Vietnam","volume":"17","author":"Marchand","year":"2011"},{"key":"b5","series-title":"Plasmodium knowlesi: Old Story but New Fact in Southeast Asia","author":"Veeranoot Nissapatorn","year":"2010"},{"key":"b6","series-title":"J Infect Dis Antimicrob Agents","first-page":"91","article-title":"A first case of Plasmodium knowlesi malaria in Phramongkutklao Hospital","volume":"31","author":"Traipattanakul","year":"2014"},{"key":"b7","series-title":"Malar J","first-page":"357","article-title":"Transfusion-transmitted severe Plasmodium knowlesi malaria in a splenectomized patient with beta-thalassaemia major in Sabah, Malaysia: a case report","volume":"15","author":"Bird","year":"2016"},{"key":"b8","series-title":"Am J Trop Med Hyg","first-page":"355","article-title":"Experimental mosquito-transmission of Plasmodium knowlesi to man and monkey","volume":"17","author":"Chin","year":"1968"},{"key":"b9","series-title":"Science","first-page":"865","article-title":"A naturally acquired quotidian-type malaria in man transferable to monkeys","volume":"149","author":"Chin","year":"1965"},{"key":"b10","series-title":"Trends Parasitol","first-page":"406","article-title":"Knowlesi malaria: newly emergent and of public health importance?","volume":"24","author":"Cox-Singh","year":"2008"},{"key":"b11","series-title":"Emerg Infect Dis","first-page":"811","article-title":"Human infections with Plasmodium knowlesi, the Philippines","volume":"14","author":"Luchavez","year":"2008"},{"key":"b12","series-title":"BMJ Case Rep","first-page":"bcr2013009558","article-title":"Plasmodium knowlesi infection: a diagnostic challenge","volume":"2013","author":"Fan","year":"2013"},{"key":"b13","series-title":"Malar J","first-page":"249","article-title":"Human Plasmodium knowlesi infections in young children in central Vietnam","volume":"8","author":"Eede","year":"2009"},{"key":"b14","series-title":"PLoS Negl Trop Dis","first-page":"e0006244","article-title":"First case of human infection with Plasmodium knowlesi in Laos","volume":"12","author":"Iwagami","year":"2018"},{"key":"b15","series-title":"Malar J","first-page":"16","article-title":"Malaria epidemiology in central Myanmar: identification of a multi-species asymptomatic reservoir of infection","volume":"16","author":"Ghinai","year":"2017"},{"key":"b16","series-title":"Emerg Infect Dis","first-page":"2211","article-title":"Naturally acquired Plasmodium knowlesi malaria in human, Thailand","volume":"10","author":"Jongwutiwes","year":"2004"},{"key":"b17","series-title":"J Infect Dis","first-page":"1143","article-title":"Differential prevalence of Plasmodium infections and cryptic Plasmodium knowlesi malaria in humans in Thailand","volume":"199","author":"Putaporntip","year":"2009"},{"key":"b18","series-title":"J Travel Med","first-page":"357","article-title":"Plasmodium knowlesi: clinical presentation and laboratory diagnosis of the first human case in a Scottish traveler","volume":"21","author":"Cordina","year":"2014"},{"key":"b19","series-title":"BMC Infect Dis","first-page":"148","article-title":"Plasmodium knowlesi infection in a returning German traveller from Thailand: a case report on an emerging malaria pathogen in a popular low-risk travel destination","volume":"18","author":"Froeschl","year":"2018"},{"key":"b20","series-title":"Emerg Infect Dis","first-page":"1434","article-title":"Monkey malaria in a European traveler returning from Malaysia","volume":"14","author":"Kantele","year":"2008"},{"key":"b21","series-title":"MMWR Morb Mortal Wkly Rep","first-page":"229","article-title":"Simian malaria in a U.S. traveler\u2013New York, 2008","volume":"58","author":"Centers for Disease Control and Prevention","year":"2009"},{"key":"b22","series-title":"Taiwan Epidemiol Bull","first-page":"178","article-title":"A case report of Simian malaria, Plasmodium knowlesi, in a Taiwanese traveler from Palawan Island, the Philippines","volume":"25","author":"Kuo","year":"2009"},{"key":"b23","series-title":"Malar J","first-page":"128","article-title":"First case of Plasmodium knowlesi infection in a Japanese traveller returning from Malaysia","volume":"12","author":"Tanizaki","year":"2013"},{"key":"b24","series-title":"J Clin Microbiol","first-page":"2523","article-title":"Molecular detection of Plasmodium knowlesi in a Dutch traveler by real-time PCR","volume":"50","author":"Link","year":"2012"},{"key":"b25","series-title":"Emerg Infect Dis","first-page":"1799","article-title":"Plasmodium knowlesi malaria in humans and macaques, Thailand","volume":"17","author":"Jongwutiwes","year":"2011"},{"key":"b26","series-title":"Malar J","first-page":"36","article-title":"Human Plasmodium knowlesi infection in Ranong province, southwestern border of Thailand","volume":"11","author":"Sermwittayawong","year":"2012"},{"key":"b27","series-title":"Thailand Malaria Elimination Program","author":"ThaiMoPH","year":"2017"},{"key":"b28","series-title":"Am J Trop Med Hyg","first-page":"1164","article-title":"Indigenous Plasmodium malariae infection in an endemic population at the Thai-Myanmar border","volume":"100","author":"Yorsaeng","year":"2019"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/101\/6\/article-p1397.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/101\/6\/article-p1397.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/101\/6\/article-p1397.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T21:44:47Z","timestamp":1722462287000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/101\/6\/article-p1397.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,4]]},"references-count":28,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.19-0063","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,4]]}}}