{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:14:26Z","timestamp":1722471266423},"reference-count":10,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,5,1]]},"abstract":"<jats:p>Brett-Major and others remind us that pathogen lists for emerging infectious diseases aid in the development of tools that target specific pathogens (e.g., vaccines) and help attract financial support. These lists tell us what we need to have, not what we need to do. The authors call for more research on ways to prevent these diseases (e.g., platform technologies for vaccines) and mitigate disease impact. Vaccines and new treatments that target individual pathogens have many limitations. However, we might save lives by treating patients with inexpensive generic drugs that target common features of the host response to infection. Undertaking research on this approach to treatment is what we need to do.<\/jats:p>","DOI":"10.4269\/ajtmh.19-0084","type":"journal-article","created":{"date-parts":[[2019,3,19]],"date-time":"2019-03-19T07:00:29Z","timestamp":1552978829000},"page":"1056-1057","source":"Crossref","is-referenced-by-count":2,"title":["Pathogen Lists Do Not Tell Us What We Need to Do"],"prefix":"10.4269","volume":"100","author":[{"given":"David S.","family":"Fedson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Am J Trop Med Hyg","first-page":"1052","article-title":"Consequences of pathogen lists: why some diseases may continue to plague us","volume":"100","author":"Brett-Major","year":"2019"},{"key":"b2","series-title":"Hum Vaccin Immunother","first-page":"790","article-title":"Clinician-initiated research on treating the host response to pandemic influenza","volume":"14","author":"Fedson","year":"2017"},{"key":"b3","series-title":"Expert Opin Biol Ther","first-page":"159","article-title":"From bench to almost bedside: the long road to a licensed Ebola virus vaccine","volume":"18","author":"Wong","year":"2018"},{"key":"b4","series-title":"Hum Vaccin Immunother","first-page":"2755","article-title":"Vaccines for epidemic infections and the role of CEPI","volume":"13","author":"Plotkin","year":"2017"},{"key":"b5","series-title":"J Infect Dis","first-page":"S7","article-title":"The damage-response framework as a tool for the physician-scientist to understand the pathogenesis of infectious diseases","volume":"218","author":"Pirofski","year":"2018"},{"key":"b6","series-title":"Ann Transl Med","first-page":"421","article-title":"Treating the host response to emerging virus diseases: lessons learned from sepsis, pneumonia, influenza and Ebola","volume":"4","author":"Fedson","year":"2016"},{"key":"b7","series-title":"Evol Med Public Health","first-page":"260","article-title":"Influenza, evolution, and the next pandemic","volume":"1","author":"Fedson","year":"2018"},{"key":"b8","series-title":"Nat Rev Immunol","first-page":"104","article-title":"Statins: a viable candidate for host-directed therapy against infectious diseases","volume":"19","author":"Parihar","year":"2018"},{"key":"b9","series-title":"Curr Gastroenterol Rep","first-page":"376","article-title":"Oral rehydration therapy in the second decade of the twenty-first century","volume":"16","author":"Binder","year":"2014"},{"key":"b10","series-title":"Antimicrob Agents Chemother","first-page":"e02228-16","article-title":"Evidence to support continuation of statin therapy in patients with Staphylococcus aureus bacteremia","volume":"61","author":"Caffrey","year":"2017"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/100\/5\/article-p1056.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/100\/5\/article-p1056.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/100\/5\/article-p1056.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T14:10:24Z","timestamp":1722435024000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/100\/5\/article-p1056.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,1]]},"references-count":10,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.19-0084","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"type":"print","value":"0002-9637"},{"type":"electronic","value":"1476-1645"}],"subject":[],"published":{"date-parts":[[2019,5,1]]}}}