{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T15:42:24Z","timestamp":1774626144197,"version":"3.50.1"},"reference-count":41,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,7,3]]},"abstract":"<jats:p>In 2016, the World Health Assembly endorsed the Global Health Sector Strategy on Viral Hepatitis, which calls for elimination of hepatitis B virus (HBV) by 2030 (definition: \u2264 0.1% hepatitis B surface antigen [HBsAg] prevalence among children aged 5 years). The burden of chronic HBV infection among children in Haiti is unknown. We conducted a nationally representative cross-sectional serological survey among 5- to 7-year-old children based on a two-stage cluster design with two strata: West (includes metropolitan Port-au-Prince) and non-West (all other departments). We collected demographic, socioeconomic, and vaccination history data and tested for HBsAg using a rapid point-of-care test. We estimated HBsAg prevalence and evaluated the association of HBV infection with vaccination history, demographics, and socioeconomic characteristics. Of the 1,152 children, seven (0.5%, 95% CI: 0.2\u20131.2) were HBsAg positive. The HBsAg prevalence varied by region (West: 0.1%, 95% CI: 0.01\u20130.9; non-West: 0.7%, 95% CI: 0.2\u20131.9) (<jats:italic>P<\/jats:italic> = 0.1), gender (males: 0.7%, 95% CI: 0.2\u20132.4; females: 0.2%, 95% CI: 0.05\u20131.1) (<jats:italic>P<\/jats:italic> = 0.3), and caregiver\u2019s education level (none: 0.8%, 95% CI: 0.2\u20133.1; some or completed primary: 0.5%, 95% CI: 0.1\u20131.8; some secondary: 0.4%, 95% CI: 0.1\u20131.8; secondary and higher: 0.0%, 95% CI: 0\u20130), although the differences were not statistically significant. None of the HBsAg-positive children had documented vaccination with hepatitis B vaccine (HepB). Haiti\u2019s chronic HBV infection prevalence among children is low; however, it is above the elimination target. To reach elimination, Haiti needs to achieve high coverage with the three HepB doses and introduce a HepB birth dose.<\/jats:p>","DOI":"10.4269\/ajtmh.19-0117","type":"journal-article","created":{"date-parts":[[2019,5,21]],"date-time":"2019-05-21T07:01:10Z","timestamp":1558422070000},"page":"214-219","source":"Crossref","is-referenced-by-count":11,"title":["Prevalence of Chronic Hepatitis B Virus Infection among Children in Haiti, 2017"],"prefix":"10.4269","volume":"101","author":[{"given":"Lana","family":"Childs","sequence":"first","affiliation":[{"name":"Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia;"},{"name":"Oak Ridge Institute for Science and Education, Centers for Disease Control and Prevention, Atlanta, Georgia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Adrien","sequence":"additional","affiliation":[{"name":"Directorate of Epidemiology, Laboratory and Research, Ministry of Public Health and Population, Port-au-Prince, Haiti;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna A.","family":"Minta","sequence":"additional","affiliation":[{"name":"Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeannot","family":"Fran\u00e7ois","sequence":"additional","affiliation":[{"name":"Expanded Program on Immunization, Ministry of Public Health and Population, Port-au-Prince, Haiti;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nadia","family":"Pha\u00efmyr Jn Charles","sequence":"additional","affiliation":[{"name":"Centers for Disease Control and Prevention, Port-au-Prince, Haiti;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valery","family":"Blot","sequence":"additional","affiliation":[{"name":"Institut Ha\u00eftien de l\u2019Enfance, P\u00e9tion-Ville, Haiti;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gloria","family":"Rey-Benito","sequence":"additional","affiliation":[{"name":"Pan American Health Organization, Washington, District of Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jodi L.","family":"Vanden Eng","sequence":"additional","affiliation":[{"name":"Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rania A.","family":"Tohme","sequence":"additional","affiliation":[{"name":"Global Immunization Division, Centers for Disease Control and Prevention, Atlanta, Georgia;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Global Hepatitis Report","author":"World Health Organization","year":"2017"},{"key":"b2","series-title":"Global Health Sector Strategy on Viral Hepatitis, 2016\u20132021","author":"World Health Organization","year":"2016"},{"key":"b3","series-title":"Resolution CD54.R7 Plan of Action for the Prevention and Control of Viral Hepatitis","author":"Pan American Health Organization","year":"2015"},{"key":"b4","series-title":"EMTCT Plus Framework for Elimination of Mother-to-Child Transmission of HIV, Syphilis, Hepatitis B, and Chagas","author":"Pan American Health Organization","year":"2017"},{"key":"b5","series-title":"Wkly Epidemiol Rec","first-page":"369","article-title":"Hepatitis B vaccines","volume":"92","author":"World Health Organization","year":"2017"},{"key":"b6","series-title":"Global and Regional Immunization Profile: Region of the Americas WHO\/UNICEF Coverage Estimates for 1980\u20132017","author":"World Health Organization","year":"2017"},{"key":"b7","series-title":"WHO Vaccine Preventable Diseases: Monitoring System","author":"World Health Organization","year":"2017"},{"key":"b8","series-title":"J Infect Dis","first-page":"418","article-title":"Herpes simplex virus type 2 infection, syphilis, and hepatitis B virus infection in Haitian women with human immunodeficiency virus type 1 and human T lymphotropic virus type 1 infections. 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