{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,25]],"date-time":"2025-11-25T06:53:50Z","timestamp":1764053630217},"reference-count":42,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,9,4]]},"abstract":"<jats:p>Mass deworming of school-aged children with anthelmintics has been recognized as an effective approach for reducing the burden of soil-transmitted helminth (STH) infections. However, the consequences of this intervention on nontargeted parasite populations sharing the same gastrointestinal niche are unclear. We conducted a cross-sectional survey among three primary schools in Sululta town, Ethiopia, to examine the association between students\u2019 histories of deworming treatment in the past 6 months and the prevalence of cestode and protozoan infections. An interviewer-led questionnaire administered to parents provided information on sociodemographic factors, and deworming status was ascertained from school records. Stool samples were collected from 525 children for microscopic examination. The independent associations of \u201c<jats:italic>any cestode<\/jats:italic>\u201d (positive either for <jats:italic>Hymenolepis nana<\/jats:italic> or <jats:italic>Taenia<\/jats:italic> spp. eggs) and \u201c<jats:italic>any protozoan\u201d<\/jats:italic> (positive either for <jats:italic>Giardia lamblia<\/jats:italic> or <jats:italic>Entamoeba histolytica\/Entamoeba dispar<\/jats:italic>) with history of deworming were examined using logistic regression. Overall, 25.9% of children were infected with at least one intestinal parasite of which <jats:italic>H. nana<\/jats:italic> was the most common. In multivariate analyses, deworming in the past 6 months was positively associated with increased odds of both \u201c<jats:italic>any protozoan<\/jats:italic>\u201d and \u201c<jats:italic>any cestode<\/jats:italic>\u201d infections; the latter reached statistical significance (AOR = 1.83, 95% CI: 0.69\u20134.86, <jats:italic>P<\/jats:italic> = 0.220, AOR = 3.82, 95% CI: 1.17\u201312.73, <jats:italic>P<\/jats:italic> = 0.029, respectively). If this observed association is causal, a greater understanding of interspecies interactions within the gastrointestinal niche may elucidate possible consequences of mass deworming treatments against STHs on coexisting nontargeted parasites.<\/jats:p>","DOI":"10.4269\/ajtmh.19-0284","type":"journal-article","created":{"date-parts":[[2019,7,23]],"date-time":"2019-07-23T07:01:07Z","timestamp":1563865267000},"page":"641-649","source":"Crossref","is-referenced-by-count":6,"title":["Increased Prevalence of Cestode Infection Associated with History of Deworming among Primary School Children in Ethiopia"],"prefix":"10.4269","volume":"101","author":[{"given":"Nader","family":"Mohamed","sequence":"first","affiliation":[{"name":"Department of Biology, Colgate University, Hamilton, New York;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Muse","sequence":"additional","affiliation":[{"name":"Department of Biology, Colgate University, Hamilton, New York;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Moges","family":"Wordofa","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dessie","family":"Abera","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abiyot","family":"Mesfin","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mistire","family":"Wolde","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kassu","family":"Desta","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aster","family":"Tsegaye","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bineyam","family":"Taye","sequence":"additional","affiliation":[{"name":"Department of Biology, Colgate University, Hamilton, New York;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"year":"2003","series-title":"School Deworming at a Glance","author":"World Health Organization","key":"b1"},{"key":"b2","series-title":"Nat Rev Microbiol","first-page":"618","article-title":"Disease watch: focus: soil-transmitted helminthiasis","volume":"2","author":"Savioli","year":"2004"},{"key":"b3","series-title":"World Health Organ Tech Rep Ser","first-page":"i","article-title":"Prevention and control of schistosomiasis and soil-transmitted helminthiasis","volume":"912","author":"WHO","year":"2002"},{"key":"b4","series-title":"Lancet","first-page":"252","article-title":"Soil-transmitted helminth infections","volume":"391","author":"Jourdan","year":"2018"},{"year":"2002","series-title":"Helminth Control in School-Age Children. 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