{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:21:09Z","timestamp":1759335669844},"reference-count":20,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,2,5]]},"abstract":"<jats:p>Chagas disease, caused by the vector-borne parasite <jats:italic>Trypanosoma cruzi<\/jats:italic>, remains one of the most significant neglected tropical diseases affecting the Americas. Identifying high-risk populations is important for understanding Chagas disease transmission and directing public health resources. We recently hypothesized that Texas hunters may be at an elevated risk for contracting Chagas disease because of opportunities for vector exposure and contact with blood of infected reservoirs. To assess their unique exposure risks, we conducted a statewide screening program of Texas hunters. A total of 885 study participants were interviewed and tested for <jats:italic>T. cruzi<\/jats:italic> infection; 18 screened positive on a rapid, point-of-care test; however, none were found positive through confirmatory testing. We did find a high prevalence of reported direct contact with wildlife blood as well as triatomine and other arthropod disease vectors. This large-scale screening program represents a novel approach to better understand the vector-borne disease risk in this unique population.<\/jats:p>","DOI":"10.4269\/ajtmh.19-0310","type":"journal-article","created":{"date-parts":[[2019,12,24]],"date-time":"2019-12-24T07:00:43Z","timestamp":1577170843000},"page":"294-297","source":"Crossref","is-referenced-by-count":12,"title":["Chagas Disease Infection Prevalence and Vector Exposure in a High-Risk Population of Texas Hunters"],"prefix":"10.4269","volume":"102","author":[{"given":"Sarah M.","family":"Gunter","sequence":"first","affiliation":[{"name":"Section of Pediatric Tropical Medicine, Baylor College of Medicine and Texas Children\u2019s Hospital, Houston, Texas;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shannon E.","family":"Ronca","sequence":"additional","affiliation":[{"name":"Section of Pediatric Tropical Medicine, Baylor College of Medicine and Texas Children\u2019s Hospital, Houston, Texas;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Micaela","family":"Sandoval","sequence":"additional","affiliation":[{"name":"The University of Texas Health Science Center, School of Public Health, Houston, Texas;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberly","family":"Coffman","sequence":"additional","affiliation":[{"name":"The University of Texas Health Science Center, School of Public Health, Houston, Texas;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren","family":"Leining","sequence":"additional","affiliation":[{"name":"Section of Pediatric Tropical Medicine, Baylor College of Medicine and Texas Children\u2019s Hospital, Houston, Texas;"},{"name":"The University of Texas Health Science Center, School of Public Health, Houston, Texas;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodion","family":"Gorchakov","sequence":"additional","affiliation":[{"name":"Section of Pediatric Tropical Medicine, Baylor College of Medicine and Texas Children\u2019s Hospital, Houston, Texas;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristy O.","family":"Murray","sequence":"additional","affiliation":[{"name":"Section of Pediatric Tropical Medicine, Baylor College of Medicine and Texas Children\u2019s Hospital, Houston, Texas;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa S.","family":"Nolan","sequence":"additional","affiliation":[{"name":"Section of Pediatric Tropical Medicine, Baylor College of Medicine and Texas Children\u2019s Hospital, Houston, Texas;"},{"name":"The University of South Carolina, Arnold School of Public Health, Greenville, South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"year":"2018","series-title":"Chagas Disease (American Trypanosomiasis)- Epidmeiology","author":"WHO","key":"b1"},{"key":"b2","series-title":"Clin Microbiol Rev","first-page":"655","article-title":"Trypanosoma cruzi and Chagas\u2019 disease in the United States","volume":"24","author":"Bern","year":"2011"},{"key":"b3","series-title":"Clin Infect Dis","first-page":"e52","article-title":"An estimate of the burden of Chagas disease in the United States","volume":"49","author":"Bern","year":"2009"},{"key":"b4","series-title":"PLoS Negl Trop Dis","first-page":"e0005033","article-title":"Estimating the burden of Chagas disease in the United States","volume":"10","author":"Manne-Goehler","year":"2016"},{"key":"b5","series-title":"Circulation","first-page":"1105","article-title":"Ten-year incidence of Chagas cardiomyopa","volume":"127","author":"Sabino","year":"2013"},{"key":"b6","series-title":"N Engl J Med","first-page":"189","article-title":"Benznidazole for chronic Chagas\u2019 cardiomyopathy","volume":"374","author":"Morillo","year":"2016"},{"key":"b7","series-title":"Parasit Vectors","first-page":"197","article-title":"Knowledge, attitudes, and practices of Texas hunters: a potentially high-risk population for exposure to the parasite that causes Chagas disease","volume":"8","author":"Garcia","year":"2015"},{"key":"b8","series-title":"Emerg Infect Dis","first-page":"500","article-title":"Likely autochthonous transmission of Trypanosoma cruzi to humans, South Central Texas, USA","volume":"23","author":"Gunter","year":"2017"},{"key":"b9","series-title":"J Wildl Dis","first-page":"814","article-title":"Identification of white-tailed deer (Odocoileus virginianus) as a novel reservoir species for Trypanosoma cruzi in Texas, USA","volume":"54","author":"Gunter","year":"2018"},{"key":"b10","series-title":"Am J Trop Med Hyg","first-page":"325","article-title":"Evidence of autochthonous Chagas disease in southeastern Texas","volume":"92","author":"Garcia","year":"2015"},{"key":"b11","series-title":"Parasit Vectors","first-page":"311","article-title":"Potential novel risk factors for autochthonous and sylvatic transmission of human Chagas disease in the United States","volume":"7","author":"Garcia","year":"2014"},{"key":"b12","series-title":"PLoS Negl Trop Dis","first-page":"e1881","article-title":"A systematic review of high quality diagnostic tests for Chagas disease","volume":"6","author":"Afonso","year":"2012"},{"key":"b13","series-title":"Curr Treat Options Infect Dis","first-page":"373","article-title":"Treatment of Chagas disease in the United States","volume":"10","author":"Meymandi","year":"2018"},{"key":"b14","series-title":"PLoS Negl Trop Dis","first-page":"e0003617","article-title":"Case report: a retrospective serological analysis indicating human exposure to tick-borne relapsing fever spirochetes in Texas","volume":"9","author":"Wilder","year":"2015"},{"key":"b15","series-title":"Zoonoses Public Health","first-page":"313","article-title":"Sylvatic transmission of Trypanosoma cruzi among domestic and wildlife reservoirs in Texas, USA: a review of the historical literature","volume":"64","author":"Gunter","year":"2017"},{"key":"b16","series-title":"J Wildl Dis","first-page":"627","article-title":"Survey of feral swine (Sus scrofa) infection with the agent of Chagas disease (Trypanosoma cruzi) in Texas, 2013\u201314","volume":"52","author":"Comeaux","year":"2016"},{"year":"2017","series-title":"Chagas Stat-Pak Assay","author":"CHEMIBIO","key":"b17"},{"year":"2014","series-title":"Parasites - American Trypanosomiasis (Also Known as Chagas Disease)","author":"CDC","key":"b18"},{"key":"b19","series-title":"Epidemiol Infect","first-page":"1010","article-title":"Trypanosoma cruzi screening in Texas blood donors, 2008\u20132012","volume":"144","author":"Garcia","year":"2016"},{"key":"b20","series-title":"Am J Trop Med Hyg","first-page":"1477","article-title":"Prevalence and seroprevalence of Trypanosoma cruzi infection in a military population in Texas","volume":"97","author":"Webber","year":"2017"}],"container-title":["The American Journal of 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