{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:00:18Z","timestamp":1787166018388,"version":"build-2736575974"},"reference-count":41,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,1,8]]},"abstract":"<jats:p>\n                    The infection dynamics of\n                    <jats:italic>Opisthorchis viverrini<\/jats:italic>\n                    metacercariae was analyzed in cyprinid fish from endemic areas in Mukdahan Province, Thailand, and Khammouane Province, Lao PDR. The fish were collected during the cool-dry (November\u2013February), hot-dry (March\u2013May), and rainy (June\u2013October) seasons in 2017. They were examined by the digestion method, and the infection status was statistically analyzed by study area, season, and fish size. The prevalence (no. of fish positive\/no. of fish examined \u00d7 100) and metacercarial intensities (no. of metacercariae detected\/no. of fish positive) of\n                    <jats:italic>O. viverrini<\/jats:italic>\n                    in both study areas depended on season, being high in the cool-dry season and varying in the hot-dry and rainy seasons. In Mukdahan Province, the average prevalence was 18.3% (range 11.0\u201346.7%,\n                    <jats:italic>n<\/jats:italic>\n                    = 420) and the intensity was 4.07 \u00b1 5.86 cysts\/fish (mean \u00b1 SD), whereas in Khammouane Province, the prevalence was 51.9% (range 9.1\u201370.6%,\n                    <jats:italic>n<\/jats:italic>\n                    = 673) and the intensity was 6.67 \u00b1 12.88 cysts\/fish. Among the cyprinid fish species examined, the infection was associated with fish body size and predominantly found in\n                    <jats:italic>Hampala dispar<\/jats:italic>\n                    (86.5%),\n                    <jats:italic>Cyclocheilichthys armatus<\/jats:italic>\n                    (73.2%), and\n                    <jats:italic>Puntius brevis<\/jats:italic>\n                    (42.7%). The distribution of\n                    <jats:italic>O. viverrini<\/jats:italic>\n                    metacercariae in fish was skewed, with most of the fish having a low worm burden with an average of four to six cysts\/fish. The findings that seasonality, sampling locality, fish size, and species of fish play roles in the risk of\n                    <jats:italic>O. viverrini<\/jats:italic>\n                    infection imply that these host and environmental factors are important for the transmission dynamics and control of\n                    <jats:italic>O. viverrini<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.4269\/ajtmh.19-0432","type":"journal-article","created":{"date-parts":[[2019,11,4]],"date-time":"2019-11-04T02:01:14Z","timestamp":1572832874000},"page":"110-116","source":"Crossref","is-referenced-by-count":17,"title":["Infection Dynamics of Opisthorchis viverrini Metacercariae in Cyprinid Fishes from Two Endemic Areas in Thailand and Lao PDR"],"prefix":"10.4269","volume":"102","author":[{"given":"Jutamas","family":"Namsanor","sequence":"first","affiliation":[{"name":"Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;"},{"name":"Faculty of Medicine, Cholangiocarcinoma Research Institute (CARI), Khon Kaen University, Khon Kaen, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadda","family":"Kiatsopit","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;"},{"name":"Faculty of Medicine, Cholangiocarcinoma Research Institute (CARI), Khon Kaen University, Khon Kaen, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thewarach","family":"Laha","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ross H.","family":"Andrews","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Cholangiocarcinoma Research Institute (CARI), Khon Kaen University, Khon Kaen, Thailand;"},{"name":"Faculty of Medicine, Imperial College London, London, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trevor N.","family":"Petney","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Cholangiocarcinoma Research Institute (CARI), Khon Kaen University, Khon Kaen, Thailand;"},{"name":"Evolution and Paleontology, State Museum of Natural History Karlsruhe, Karlsruhe, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paiboon","family":"Sithithaworn","sequence":"additional","affiliation":[{"name":"Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;"},{"name":"Faculty of Medicine, Cholangiocarcinoma Research Institute (CARI), Khon Kaen University, Khon Kaen, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Parasitol Int","first-page":"10","article-title":"The current status of opisthorchiasis and clonorchiasis in the Mekong basin","volume":"61","author":"Sithithaworn","year":"2012"},{"key":"b2","series-title":"PLoS One","first-page":"e0177130","article-title":"First report and molecular identification of Opisthorchis viverrini infection in human communities from Lower Myanmar","volume":"12","author":"Aung","year":"2017"},{"key":"b3","series-title":"Adv Parasitol","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/bs.apar.2018.05.002","article-title":"Epidemiology of Opisthorchis viverrini infection","volume":"101","author":"Suwannatrai","year":"2018"},{"key":"b4","series-title":"Trends Parasitol","first-page":"497","article-title":"Opisthorchis viverrini: an underestimated parasite in world health","volume":"24","author":"Andrews","year":"2018"},{"key":"b5","series-title":"BMC Cancer","first-page":"459","article-title":"Cohort profile: cholangiocarcinoma screening and care program (CASCAP)","volume":"9","author":"Khuntikeo","year":"2015"},{"key":"b6","series-title":"IARC Monographs on the Evaluation of Carcinogen Risks to Humans","author":"IARC","year":"2011"},{"key":"b7","series-title":"J Hepatobiliary Pancreat Sci","first-page":"301","article-title":"Roles of liver fluke infection as risk factor for cholangiocarcinoma","volume":"21","author":"Sithithaworn","year":"2014"},{"key":"b8","series-title":"Korean J Parasitol","first-page":"703","article-title":"Distribution and abundance of Opisthorchis viverrini metacercariae in cyprinid fish in northeastern Thailand","volume":"51","author":"Pinlaor","year":"2013"},{"key":"b9","series-title":"Ann Parasitol Hum Comp","first-page":"238","article-title":"Larval stages of medically important flukes (Trematoda) from Vientiane Province, Laos. 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