{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:48:31Z","timestamp":1790642911053,"version":"4.1.0"},"reference-count":6,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,11,6]]},"abstract":"<jats:p>A 50-year-old Chinese woman with a history of weakness and paroxysmal seizures of the left limb presented to our hospital with a ten-day history of neck pain. Imaging showed that there was a mass in the frontal lobe of her brain. On resection of the mass, a motile worm was identified. Morphological observation and molecular analysis of the mitochondrial COX1 and 28S rRNA genes of the worm extracted from the brain identified the causative agent as <jats:italic>Spirometra mansoni<\/jats:italic>. Homology search of the polymerase chain reaction (PCR)-amplified products from the case was conducted against gene fragments from local wild frogs. High homology was found between them, showing her likely exposure was frog consumption.<\/jats:p>","DOI":"10.4269\/ajtmh.19-0468","type":"journal-article","created":{"date-parts":[[2019,8,20]],"date-time":"2019-08-20T07:00:38Z","timestamp":1566284438000},"page":"1174-1176","source":"Crossref","is-referenced-by-count":9,"title":["Case Report: Morphologic and Genetic Identification of Cerebral Sparganosis"],"prefix":"10.4269","volume":"101","author":[{"given":"Yanming","family":"Meng","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziwei","family":"Kuang","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Parasitology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Parasitol Res","first-page":"1653","article-title":"First report of sparganosis manifested by pleuritis and decreased peripheral blood eosinophils in Jiangsu province, China","volume":"118","author":"Deng","year":"2019"},{"key":"b2","series-title":"Epidemiol Infect","first-page":"2654","article-title":"Retrospective epidemiological analysis of sparganosis in mainland China from 1959 to 2012","volume":"142","author":"Lu","year":"2014"},{"key":"b3","series-title":"Mol Phylogenet Evol","first-page":"75","article-title":"Comparative mitochondrial genomics among Spirometra (Cestoda: Diphyllobothriidae) and the molecular phylogeny of related tapeworms","volume":"117","author":"Zhang","year":"2017"},{"key":"b4","series-title":"Int J Infect Dis","first-page":"41","article-title":"Prevalence of Spirometra mansoni in dogs, cats, and frogs and its medical relevance in Guangzhou, China","volume":"53","author":"Hong","year":"2016"},{"key":"b5","series-title":"PLoS One","first-page":"e0119295","article-title":"Genetic structure analysis of Spirometra erinaceieuropaei isolates from central and southern China","volume":"10","author":"Zhang","year":"2015"},{"key":"b6","series-title":"BMC Neurol","first-page":"105","article-title":"A case report: 1-year follow-up of cerebral sparganosis mansoni with a stroke-like onset","volume":"19","author":"Xie","year":"2019"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/101\/5\/article-p1174.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/101\/5\/article-p1174.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/101\/5\/article-p1174.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T15:28:26Z","timestamp":1722439706000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/101\/5\/article-p1174.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,6]]},"references-count":6,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.19-0468","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,6]]}}}