{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T17:03:49Z","timestamp":1789405429348,"version":"build-2803163510"},"reference-count":20,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,10,2]]},"abstract":"<jats:p>Madariaga virus (MADV), previously known as South American eastern equine encephalitis virus (SA EEEV; family Togaviridae, genus <jats:italic>Alphavirus<\/jats:italic>), is a mosquito-borne virus associated mainly with equine disease. In 2010, the first human outbreak by MADV was reported in Central America, but the mosquito vectors and vertebrate hosts involved in the outbreak were not identified. In Argentina, the first epizootic of MADV was in 1930, and since then, several epizootics by MADV have been reported. However, the potential vectors and hosts involved in the transmission cycle remain unknown. In the present study, MADV was detected in <jats:italic>Culex<\/jats:italic> (<jats:italic>Culex<\/jats:italic>) spp. mosquitoes and the phylogenetic analysis showed that the MADV fragment amplified grouped with the lineage\/subtype III of the SA EEEV complex. Our results provide information about the natural infection with MADV in mosquitoes collected in a wild environment of Argentina and its genetic relatedness.<\/jats:p>","DOI":"10.4269\/ajtmh.19-0475","type":"journal-article","created":{"date-parts":[[2019,9,4]],"date-time":"2019-09-04T12:28:41Z","timestamp":1567600121000},"page":"916-918","source":"Crossref","is-referenced-by-count":10,"title":["First Detection of Madariaga virus in Mosquitoes Collected in a Wild Environment of Northeastern Argentina"],"prefix":"10.4269","volume":"101","author":[{"given":"Ornela Sofia","family":"Stechina","sequence":"first","affiliation":[{"name":"Laboratorio de Entomolog\u00eda, Instituto de Medicina Regional, Universidad Nacional del Nordeste, Chaco, Argentina;"},{"name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas (CONICET), Buenos Aires, Argentina;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Griselda In\u00e9s","family":"Oria","sequence":"additional","affiliation":[{"name":"Laboratorio de Entomolog\u00eda, Instituto de Medicina Regional, Universidad Nacional del Nordeste, Chaco, Argentina;"},{"name":"Facultad de Medicina, Universidad Nacional del Nordeste, Corrientes, Argentina;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Torres","sequence":"additional","affiliation":[{"name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas (CONICET), Buenos Aires, Argentina;"},{"name":"C\u00e1tedra de Virolog\u00eda, Facultad de Farmacia y Bioqu\u00edmica, Universidad de Buenos Aires, Buenos Aires, Argentina;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis Adri\u00e1n","family":"Diaz","sequence":"additional","affiliation":[{"name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas (CONICET), Buenos Aires, Argentina;"},{"name":"Facultad de Ciencias M\u00e9dicas, Instituto de Virolog\u00eda \u201cDr. J.M. Vanella,\u201d Universidad Nacional de C\u00f3rdoba, C\u00f3rdoba, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Contigiani","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias M\u00e9dicas, Instituto de Virolog\u00eda \u201cDr. J.M. Vanella,\u201d Universidad Nacional de C\u00f3rdoba, C\u00f3rdoba, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Stein","sequence":"additional","affiliation":[{"name":"Laboratorio de Entomolog\u00eda, Instituto de Medicina Regional, Universidad Nacional del Nordeste, Chaco, Argentina;"},{"name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas (CONICET), Buenos Aires, Argentina;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"J Exp Med","first-page":"547","article-title":"Antigenic variants of eastern equine encephalitis virus","volume":"119","author":"Casals","year":"1964"},{"key":"b2","series-title":"Am J Trop Med Hyg","first-page":"579","article-title":"Genetic and antigenic diversity among eastern equine encephalitis viruses from North, Central, and South America","volume":"61","author":"Brault","year":"1999"},{"key":"b3","series-title":"Virus Taxonomy: Classification and Nomenclature of Viruses. 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