{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T10:39:12Z","timestamp":1780569552761,"version":"3.54.1"},"reference-count":42,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,3,5]]},"DOI":"10.4269\/ajtmh.19-0523","type":"journal-article","created":{"date-parts":[[2020,1,14]],"date-time":"2020-01-14T07:00:59Z","timestamp":1578985259000},"page":"541-546","source":"Crossref","is-referenced-by-count":24,"title":["Association of Helicobacter pylori Infection with Vitamin D Deficiency in Infants and Toddlers"],"prefix":"10.4269","volume":"102","author":[{"given":"Ting","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Neurology, The Affiliated Children\u2019s Hospital of Xi\u2019an Jiaotong University, Xi\u2019an Shaanxi, China"},{"name":"Department of Pediatrics, Central South University Third Xiangya Hospital, Changsha, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengwen","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Central South University Third Xiangya Hospital, Changsha, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Central South University Third Xiangya Hospital, Changsha, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peipei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Central South University Third Xiangya Hospital, Changsha, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjuan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Central South University Third Xiangya Hospital, Changsha, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Central South University Third Xiangya Hospital, Changsha, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingling","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Central South University Third Xiangya Hospital, Changsha, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","doi-asserted-by":"crossref","first-page":"2878","DOI":"10.1007\/s10620-009-1091-y","article-title":"Impact of H. pylori on growth: is the infection or mucosal disease related to growth impairment?","volume":"55","author":"Gulcan","year":"2010","journal-title":"Dig Dis Sci"},{"key":"b2","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1007\/s00277-016-2618-x","article-title":"Severe Helicobacter pylori gastritis-related thrombocytopenia and iron deficiency anemia in an adolescent female","volume":"95","author":"Todo","year":"2016","journal-title":"Ann Hematol"},{"key":"b3","doi-asserted-by":"crossref","first-page":"336","DOI":"10.3109\/09537104.2014.911836","article-title":"Helicobacter pylori infection & immune thrombocytopenic purpura in children and adolescents: a randomized controlled trial","volume":"26","author":"Brito","year":"2015","journal-title":"Platelets"},{"key":"b4","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.aller.2017.03.004","article-title":"Helicobacter pylori seropositivity protects against childhood asthma and inversely correlates to its clinical and functional severity","volume":"46","author":"Fouda","year":"2018","journal-title":"Allergol Immunopathol (Madr)"},{"key":"b5","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1111\/cea.12995","article-title":"Association between infection with Helicobacter pylori and atopy in young Ethiopian children: a longitudinal study","volume":"47","author":"Taye","year":"2017","journal-title":"Clin Exp Allergy"},{"key":"b6","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1111\/ppe.12374","article-title":"Helicobacter pylori seropositivity and childhood neurodevelopment, the Rhea birth cohort in crete, Greece","volume":"3","author":"Karachaliou","year":"2017","journal-title":"Paediatr Perinat Epidemiol"},{"key":"b7","doi-asserted-by":"crossref","first-page":"110","DOI":"10.5223\/pghn.2016.19.2.110","article-title":"The association between Helicobacter pylori infection and body weight among children","volume":"19","author":"Choi","year":"2016","journal-title":"Pediatr Gastroenterol Hepatol Nutr"},{"key":"b8","first-page":"1798","article-title":"Helicobacter pylori infection in children: should it be carefully assessed?","volume":"20","author":"Ortiz-Princz","year":"2016","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"b9","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1038\/mi.2016.131","article-title":"Helicobacter pylori infection is associated with an altered gastric microbiota in children","volume":"10","author":"Brawner","year":"2017","journal-title":"Mucosal Immunol"},{"key":"b10","doi-asserted-by":"crossref","first-page":"12781","DOI":"10.3748\/wjg.v20.i36.12781","article-title":"Beyond the stomach: an updated view of Helicobacter pylori pathogenesis, diagnosis, and treatment","volume":"20","author":"Testerman","year":"2014","journal-title":"World J Gastroenterol"},{"key":"b11","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1007\/s00284-017-1256-4","article-title":"Role of flagella in the pathogenesis of Helicobacter pylori","volume":"74","author":"Gu","year":"2017","journal-title":"Curr Microbiol"},{"key":"b12","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1097\/EDE.0b013e3181fe7e31","article-title":"Effect of Helicobacter pylori infection on growth velocity of school-age andean children","volume":"22","author":"Goodman","year":"2011","journal-title":"Epidemiology"},{"key":"b13","first-page":"269","article-title":"Influence of Helicobacter pylori infection on chosen parameters physical development of children and youth","volume":"22","author":"Zielinska-Duda","year":"2007","journal-title":"Pol Merkur Lekarski"},{"key":"b14","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1111\/1751-2980.12793","article-title":"Influence of serum vitamin D level on Helicobacter pylori eradication: a multi-center, observational, prospective and cohort study","volume":"20","author":"Han","year":"2019","journal-title":"J Dig Dis"},{"key":"b15","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1007\/s00431-017-2903-2","article-title":"Vitamin D in European children-statement from the European Academy of Paediatrics (EAP)","volume":"176","author":"Grossman","year":"2017","journal-title":"Eur J Pediatr"},{"key":"b16","doi-asserted-by":"crossref","first-page":"412","DOI":"10.4292\/wjgpt.v7.i3.412","article-title":"Chinese Helicobacter pylori vaccine: solution for an old challenge?","volume":"7","author":"Talebi Bezmin","year":"2016","journal-title":"World J Gastrointest Pharmacol Ther"},{"key":"b17","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1053\/j.gastro.2017.04.022","article-title":"Global prevalence of Helicobacter pylori infection: systematic review and meta-analysis","volume":"155","author":"Hooi","year":"2017","journal-title":"Gastroenterology"},{"key":"b18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1523-5378.2010.00779.x","article-title":"Epidemiology of Helicobacter pylori infection and public health implications","volume":"15","author":"Ford","year":"2010","journal-title":"Helicobacter Null"},{"key":"b19","doi-asserted-by":"crossref","first-page":"2570","DOI":"10.1038\/ajg.2010.324","article-title":"Epidemiology of peptic ulcer disease: endoscopic results of the systematic investigation of gastrointestinal disease in China","volume":"105","author":"Li","year":"2010","journal-title":"Am J Gastroenterol"},{"key":"b20","doi-asserted-by":"crossref","first-page":"e12399","DOI":"10.1111\/hel.12399","article-title":"Review: prevalence and dynamics of Helicobacter pylori infection during childhood","volume":"22","author":"Zabala","year":"2017","journal-title":"Helicobacter"},{"key":"b21","doi-asserted-by":"crossref","first-page":"426","DOI":"10.4161\/gmic.26943","article-title":"Role of childhood infection in the sequelae of H. pylori disease","volume":"4","author":"Harris","year":"2013","journal-title":"Gut Microbes"},{"key":"b22","doi-asserted-by":"crossref","first-page":"11221","DOI":"10.3748\/wjg.v21.i40.11221","article-title":"Diagnosis of Helicobacter pylori infection: current options and developments","volume":"21","author":"Wang","year":"2015","journal-title":"World J Gastroenterol"},{"key":"b23","doi-asserted-by":"crossref","first-page":"309","DOI":"10.4103\/sjg.SJG_531_18","article-title":"Where are we today with Helicobacter pylori infection among healthy children in Saudi Arabia?","volume":"25","author":"Al-Hussaini","year":"2019","journal-title":"Saudi J Gastroenterol"},{"key":"b24","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/hel.12172","article-title":"Prevalence and risk factors of Helicobacter pylori infection in Saudi children: a three-year prospective controlled study","volume":"20","author":"Hasosah","year":"2015","journal-title":"Helicobacter"},{"key":"b25","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1111\/apt.13364","article-title":"Prevalence and risk factors of Helicobacter pylori infection in asymptomatic Chinese children: a prospective, cross-sectional, population-based study","volume":"42","author":"Ding","year":"2015","journal-title":"Aliment Pharmacol Ther"},{"key":"b26","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.4269\/ajtmh.2009.09-0107","article-title":"Association of Helicobacter pylori infection and height of Mexican children of low socioeconomic level attending boarding schools","volume":"81","author":"Vilchis","year":"2009","journal-title":"Am J Trop Med Hyg"},{"key":"b27","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1111\/j.1442-200X.2007.02444.x","article-title":"Association of Helicobacter pylori infection with gastroduodenal disease, epidemiologic factors and iron-deficiency anemia in Turkish children undergoing endoscopy, and impact on growth","volume":"49","author":"S\u00fcoglu","year":"2007","journal-title":"Pediatr Int"},{"key":"b28","doi-asserted-by":"crossref","first-page":"e788","DOI":"10.1016\/j.ijid.2010.03.013","article-title":"The effect of Helicobacter pylori infection on growth velocity in young children from poor urban communities in Ecuador","volume":"14","author":"Egorov","year":"2010","journal-title":"Int J Infect Dis"},{"key":"b29","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1111\/j.1651-2227.2009.01221.x","article-title":"Helicobacter pylori, helminth infections and growth: a cross-sectional study in a high prevalence population","volume":"98","author":"Cherian","year":"2009","journal-title":"Acta Paediatr"},{"key":"b30","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1017\/S0007114515000483","article-title":"Dietary and anthropometric indicators of nutritional status in relation to Helicobacter pylori infection in a paediatric population","volume":"113","author":"Janjetic","year":"2015","journal-title":"Br J Nutr"},{"key":"b31","doi-asserted-by":"crossref","first-page":"126","DOI":"10.5152\/eurasianjmed.2015.104","article-title":"Serum zinc, copper, magnesium and selenium levels in children with Helicobacter pylori infection","volume":"47","author":"Ozturk","year":"2015","journal-title":"Eurasian J Med"},{"key":"b32","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s12011-018-1283-4","article-title":"Serum concentrations of 15 elements among Helicobacter pylori-infected residents from Lujiang county with high gastric cancer risk in Eastern China","volume":"186","author":"Hu","year":"2018","journal-title":"Biol Trace Elem Res"},{"key":"b33","first-page":"364","article-title":"Helicobacter pylori gastritis manifested by acute anemia. Ann Pediatr (Paris)","volume":"40","author":"Bruel","year":"1993","journal-title":"Ann Pediatr (Paris)"},{"key":"b34","first-page":"64","article-title":"Severe anemia and Helicobacter pylori infection in school age children; A case reports","volume":"6","author":"Gheibi","year":"2016","journal-title":"Iran J Ped Hematol Oncol"},{"key":"b35","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1017\/S0007114515000999","article-title":"Vitamin D deficiency is associated with anaemia among African Americans in a US cohort","volume":"113","author":"Smith","year":"2015","journal-title":"Br J Nutr"},{"key":"b36","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.nut.2017.09.008","article-title":"Poor vitamin D status increases the risk of anemia in school children: national food and nutrition surveillance","volume":"47","author":"Nikooyeh","year":"2018","journal-title":"Nutrition"},{"key":"b37","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1097\/MED.0000000000000199","article-title":"Vitamin D and anemia: insights into an emerging association","volume":"22","author":"Smith","year":"2015","journal-title":"Curr Opin Endocrinol Diabetes Obes"},{"key":"b38","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1017\/S1368980017002816","article-title":"Vitamin D status is associated with underweight and stunting in children aged 6\u201336 months residing in the Ecuadorian Andes","volume":"21","author":"Mokhtar","year":"2018","journal-title":"Public Health Nutr"},{"key":"b39","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.17219\/acem\/65430","article-title":"The influence of vitamin D deficiency on eradication rates of Helicobacter pylori","volume":"26","author":"Yildirim","year":"2017","journal-title":"Adv Clin Exp Med"},{"key":"b40","doi-asserted-by":"crossref","first-page":"103","DOI":"10.3164\/jcbn.38.103","article-title":"Inhibitory effect of long term 1 \u03b1 -hydroxy vitamin D3 administration on Helicobacter pylori infection","volume":"38","author":"Kawaura","year":"2006","journal-title":"J Clin Biochem Nutr"},{"key":"b41","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/hel.12102","article-title":"Helicobacter pylori induces increased expression of the vitamin d receptor in immune responses","volume":"19","author":"Guo","year":"2014","journal-title":"Helicobacter"},{"key":"b42","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1080\/15548627.2018.1557835","article-title":"Vitamin D3 activates the autolysosomal degradation function against Helicobacter pylori through the PDIA3 receptor in gastric epithelial cells","volume":"15","author":"Hu","year":"2019","journal-title":"Autophagy"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"language":"en","deposited":{"date-parts":[[2021,1,27]],"date-time":"2021-01-27T17:37:02Z","timestamp":1611769022000},"score":1,"resource":{"primary":{"URL":"https:\/\/ajtmh.org\/doi\/10.4269\/ajtmh.19-0523"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,5]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,3,5]]}},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.19-0523","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,5]]}}}