{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:47:35Z","timestamp":1790628455272,"version":"4.1.0"},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","license":[{"start":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T00:00:00Z","timestamp":1617753600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,4,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>There is a high prevalence of blood-borne infections in West Africa. This study sought to determine the seroprevalence of blood-borne infections, including hepatitis B virus (HBV), hepatitis C virus (HCV), HIV, and syphilis, in blood donors in Burkina Faso. Blood donors were recruited from 2009 to 2013 in four major cities in Burkina Faso of urban area (Ouagadougou) and rural area (Bobo Dioulasso, Fada N\u2019Gourma, and Ouahigouya). Serology tests including hepatitis B surface antigen, anti-HCV, anti-HIV, and rapid plasma reagin test were used for screening and were confirmed with ELISA. Disease prevalence was calculated among first-time donors. Incidence and residual risk were calculated from repeat donors. There were 166,681 donors; 43,084 had \u2265 2 donations. The overall seroprevalence of HBV, HCV, HIV, and syphilis were 13.4%, 6.9%, 2.1%, and 2.4%, respectively. The incidence rates (IRs) of HBV, HCV, HIV, and syphilis infection were 2,433, 3,056, 1,121, and 1,287 per 100,000 person-years. There was lower seroprevalence of HBV and HCV in urban area than in rural area (12.9% versus 14.0%, <jats:italic>P<\/jats:italic> &lt; 0.001; and 5.9% versus 8.0%, <jats:italic>P<\/jats:italic> &lt; 0.001), and no difference in HIV (2.1% versus 2.1%, <jats:italic>P<\/jats:italic> = 0.25). The IRs of new HBV, HCV, HIV, and syphilis were 2.43, 3.06, 1.12, and 1.29 per 100,000 person-years, respectively. The residual risk was one per 268 donations for HBV, one per 181 donations for HCV, and one per 1,480 donations for HIV, respectively. In conclusion, this comprehensive study from four blood donation sites in Burkina Faso showed high HBV and HCV seroprevalence and incidence with high residual risk from blood donation.<\/jats:p>","DOI":"10.4269\/ajtmh.20-0601","type":"journal-article","created":{"date-parts":[[2021,2,22]],"date-time":"2021-02-22T17:47:12Z","timestamp":1614016032000},"page":"1577-1581","source":"Crossref","is-referenced-by-count":17,"title":["Distribution and Incidence of Blood-Borne Infection among Blood Donors from Regional Transfusion Centers in Burkina Faso: A Comprehensive Study"],"prefix":"10.4269","volume":"104","author":[{"given":"Nicha","family":"Wongjarupong","sequence":"first","affiliation":[{"name":"1Gastroenterology and Hepatology, Mayo Clinic Rochester, Rochester, Minnesota;"},{"name":"2Department of Medicine, University of Minnesota, Minneapolis, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharad","family":"Oli","sequence":"additional","affiliation":[{"name":"1Gastroenterology and Hepatology, Mayo Clinic Rochester, Rochester, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahamoudou","family":"Sanou","sequence":"additional","affiliation":[{"name":"3Centre de Recherche Biomol\u00e9culaire Pietro Annigoni (CERBA)\/LABIOGENE, University of Ouaga I Joseph Ki Zerbo (JKZ), Ouagadougou, Burkina Faso;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florencia","family":"Djigma","sequence":"additional","affiliation":[{"name":"3Centre de Recherche Biomol\u00e9culaire Pietro Annigoni (CERBA)\/LABIOGENE, University of Ouaga I Joseph Ki Zerbo (JKZ), Ouagadougou, Burkina Faso;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Kiba Koumare","sequence":"additional","affiliation":[{"name":"3Centre de Recherche Biomol\u00e9culaire Pietro Annigoni (CERBA)\/LABIOGENE, University of Ouaga I Joseph Ki Zerbo (JKZ), Ouagadougou, Burkina Faso;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert T.","family":"Yonli","sequence":"additional","affiliation":[{"name":"3Centre de Recherche Biomol\u00e9culaire Pietro Annigoni (CERBA)\/LABIOGENE, University of Ouaga I Joseph Ki Zerbo (JKZ), Ouagadougou, Burkina Faso;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed A.","family":"Hassan","sequence":"additional","affiliation":[{"name":"1Gastroenterology and Hepatology, Mayo Clinic Rochester, Rochester, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristin","family":"Mara","sequence":"additional","affiliation":[{"name":"4Division of Biomedical Statistics and Informatics, Mayo Clinic Rochester, Rochester, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William S.","family":"Harmsen","sequence":"additional","affiliation":[{"name":"4Division of Biomedical Statistics and Informatics, Mayo Clinic Rochester, Rochester, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terry","family":"Therneau","sequence":"additional","affiliation":[{"name":"4Division of Biomedical Statistics and Informatics, Mayo Clinic Rochester, Rochester, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oumar","family":"Barro","sequence":"additional","affiliation":[{"name":"5Division of Hematology and Medical Oncology, Mayo Clinic Arizona, Scottsdale, Arizona;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghislaine","family":"Vodounhessi","sequence":"additional","affiliation":[{"name":"6Centre National de Transfusion sanguine du Burkina Faso (National Center for Blood Transfusion in Burkina Faso), Ouagadougou, Burkina Faso;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salam","family":"Sawadogo","sequence":"additional","affiliation":[{"name":"6Centre National de Transfusion sanguine du Burkina Faso (National Center for Blood Transfusion in Burkina Faso), Ouagadougou, Burkina Faso;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Christopher","family":"Chamcheu","sequence":"additional","affiliation":[{"name":"7School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Simpore","sequence":"additional","affiliation":[{"name":"3Centre de Recherche Biomol\u00e9culaire Pietro Annigoni (CERBA)\/LABIOGENE, University of Ouaga I Joseph Ki Zerbo (JKZ), Ouagadougou, Burkina Faso;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lewis R.","family":"Roberts","sequence":"additional","affiliation":[{"name":"1Gastroenterology and Hepatology, Mayo Clinic Rochester, Rochester, Minnesota;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bolni M.","family":"Nagalo","sequence":"additional","affiliation":[{"name":"3Centre de Recherche Biomol\u00e9culaire Pietro Annigoni (CERBA)\/LABIOGENE, University of Ouaga I Joseph Ki Zerbo (JKZ), Ouagadougou, Burkina Faso;"},{"name":"5Division of Hematology and Medical Oncology, Mayo Clinic Arizona, Scottsdale, Arizona;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/104\/4\/article-p1577.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/104\/4\/article-p1577.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T12:36:50Z","timestamp":1617799010000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/104\/4\/article-p1577.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,7]]},"references-count":0,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.20-0601","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,7]]}}}