{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T11:28:28Z","timestamp":1790162908667,"version":"4.1.0"},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p><jats:italic>Talaromyces marneffei<\/jats:italic> (<jats:italic>T. marneffei<\/jats:italic>), formerly <jats:italic>Penicillium marneffei<\/jats:italic>, is a dimorphic fungus prevalent in Southeast Asia that can cause severe systemic infection, especially in immunocompromised patients. There are few reports about the use of posaconazole in <jats:italic>T. marneffei<\/jats:italic> infection. Here, we present a case of pulmonary <jats:italic>T. marneffei<\/jats:italic> infection in a renal transplant recipient. The patient responded rapidly to oral posaconazole administration but experienced serum creatinine fluctuation because of the interaction between posaconazole and immunosuppressants. Seven months after adjusting the dose of immunosuppressants, the patient recovered completely. Posaconazole is a potentially promising therapy for <jats:italic>T. marneffei<\/jats:italic> infection, but it should be administered under close monitoring.<\/jats:p>","DOI":"10.4269\/ajtmh.20-0909","type":"journal-article","created":{"date-parts":[[2020,11,24]],"date-time":"2020-11-24T07:01:26Z","timestamp":1606201286000},"page":"744-747","source":"Crossref","is-referenced-by-count":16,"title":["Case Report: Successful Treatment of Pulmonary Talaromyces marneffei Infection with Posaconazole in a Renal Transplant Recipient"],"prefix":"10.4269","volume":"104","author":[{"given":"Qin","family":"Lang","sequence":"first","affiliation":[{"name":"1Department of Pulmonary and Critical Care Medicine, Sichuan Academy of Medical Sciences & Sichuan Provincial People\u2019s Hospital, Chengdu, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aamer","family":"Pasheed Chughtai","sequence":"additional","affiliation":[{"name":"2Department of Imaging Institute, Cleveland Clinic, Cleveland, Ohio;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Fang","family":"Kong","sequence":"additional","affiliation":[{"name":"3Department of Radiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People\u2019s Hospital, Chengdu, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai-Ying","family":"Yan","sequence":"additional","affiliation":[{"name":"1Department of Pulmonary and Critical Care Medicine, Sichuan Academy of Medical Sciences & Sichuan Provincial People\u2019s Hospital, Chengdu, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/104\/2\/article-p744.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/104\/2\/article-p744.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T02:15:06Z","timestamp":1612836906000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/104\/2\/article-p744.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,3]]},"references-count":0,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.20-0909","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,3]]}}}