{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T21:34:39Z","timestamp":1648848879532},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,2,1]]},"abstract":"<jats:p>Following vaccination with the live attenuated, recombinant vesicular stomatitis virus Indiana serotype Ebola virus (rVSV-EBOV) vaccine, persons may exhibit a transient vaccine-associated viremia. To investigate the potential for Old World sand flies to transmit this vaccine following feeding on a viremic person, we fed laboratory-reared <jats:italic>Phlebotomus papatasi<\/jats:italic> an artificial blood meal containing 7.2 log<jats:sub>10<\/jats:sub> plaque-forming units of rVSV-EBOV. Replication or dissemination was not detected in the body or legs of any <jats:italic>P. papatasi<\/jats:italic> collected at seven (<jats:italic>n<\/jats:italic> = 75) or 15 (<jats:italic>n<\/jats:italic> = 75) days post-feed. These results indicate a low potential for rVSV-EBOV to replicate and disseminate in <jats:italic>P. papatasi<\/jats:italic>, a species whose geographic distribution ranges from Morocco to southwest Asia and as far north as southern Europe.<\/jats:p>","DOI":"10.4269\/ajtmh.20-0951","type":"journal-article","created":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T18:02:20Z","timestamp":1612202540000},"source":"Crossref","is-referenced-by-count":1,"title":["No Evidence of rVSV-Ebola Virus Vaccine Replication or Dissemination in the Sand Fly Phlebotomus papatasi"],"prefix":"10.4269","author":[{"given":"Andrew D.","family":"Haddow","sequence":"first","affiliation":[{"name":"1United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Frederick, Maryland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobin E.","family":"Rowland","sequence":"additional","affiliation":[{"name":"2Walter Reed Army Institute of Research, Silver Spring, Maryland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah L.","family":"Norris","sequence":"additional","affiliation":[{"name":"1United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Frederick, Maryland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas R.","family":"Sprague","sequence":"additional","affiliation":[{"name":"1United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Frederick, Maryland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge O.","family":"Lopez","sequence":"additional","affiliation":[{"name":"2Walter Reed Army Institute of Research, Silver Spring, Maryland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark C.","family":"Carder","sequence":"additional","affiliation":[{"name":"2Walter Reed Army Institute of Research, Silver Spring, Maryland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yvonne-Marie","family":"Linton","sequence":"additional","affiliation":[{"name":"3Walter Reed Biosystematics Unit, Smithsonian Museum Support Center, Suitland, Maryland;"},{"name":"4Department of Entomology, Smithsonian Institution National Museum of Natural History, Washington, District of Columbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Louise M.","family":"Pitt","sequence":"additional","affiliation":[{"name":"1United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Frederick, Maryland;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/aop\/article-10.4269-ajtmh.20-0951\/article-10.4269-ajtmh.20-0951.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/aop\/article-10.4269-ajtmh.20-0951\/article-10.4269-ajtmh.20-0951.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T18:02:21Z","timestamp":1612202541000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/aop\/article-10.4269-ajtmh.20-0951\/article-10.4269-ajtmh.20-0951.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,1]]},"references-count":0,"URL":"https:\/\/doi.org\/10.4269\/ajtmh.20-0951","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,1]]}}}