{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T17:12:33Z","timestamp":1784913153466,"version":"3.55.0"},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,6,2]]},"abstract":"<jats:title>Abstract.<\/jats:title><jats:p>Distribution of long-lasting insecticide-treated nets (LLINs), passive detection and treatment with artemisinin-based combination therapy (ACT), and intermittent preventive treatment in pregnancy (IPTp) are the mainstay malaria control measures of Guinea-Bissau\u2019s national control programme. This study aimed to estimate the prevalence of <jats:italic>Plasmodium falciparum<\/jats:italic> on Bubaque, the most populous island of the country\u2019s remote Bijagos archipelago. A cross-sectional survey was performed at the start of the rainy season in August 2017. Participants were recruited using systematic random sampling in a two-stage stratified cluster design. Malaria parasitemia was detected using rapid diagnostic tests (RDTs) and quantitative PCR (qPCR). Data on housing, education, larval source management, socioeconomic status, anemia, and malaria preventive measures were collected. Multivariable logistic regression models were constructed to identify associations with <jats:italic>P. falciparum<\/jats:italic> infection. Four hundred four persons (aged 6 months\u201379 years, median 17 years) were enrolled in the study. The prevalence of <jats:italic>P. falciparum<\/jats:italic> parasitemia was 5.8% by RDT (95% CI: 3.55\u20139.33) and 16.9% by qPCR (95% CI: 13.09\u201321.71). The prevalence of anemia was 74.3% (95% CI: 69.04\u201378.85) as defined by the WHO criteria. All sampled houses were found to have open eaves; 99.5% of the surveyed population reported sleeping under a bednet (95% CI: 97.8\u201399.9). Although reported LLIN use is high, there remains an appreciable prevalence of malaria, suggesting that transmission is ongoing and further tools are required to reduce the burden of the disease.<\/jats:p>","DOI":"10.4269\/ajtmh.20-1029","type":"journal-article","created":{"date-parts":[[2021,3,29]],"date-time":"2021-03-29T15:32:42Z","timestamp":1617031962000},"page":"2117-2122","source":"Crossref","is-referenced-by-count":9,"title":["The Epidemiology of Plasmodium falciparum Malaria in the Bijagos Islands of Guinea-Bissau"],"prefix":"10.4269","volume":"104","author":[{"given":"David","family":"McGregor","sequence":"first","affiliation":[{"name":"1Clinical Research Department, London School of Hygiene and Tropical Medicine, London, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eunice","family":"Texeira da Silva","sequence":"additional","affiliation":[{"name":"1Clinical Research Department, London School of Hygiene and Tropical Medicine, London, United Kingdom;"},{"name":"2Region Sanitaria Bolama-Bijag\u00f3s, Bubaque, Guinea-Bissau;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"Grignard","sequence":"additional","affiliation":[{"name":"3Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Goncalves","sequence":"additional","affiliation":[{"name":"1Clinical Research Department, London School of Hygiene and Tropical Medicine, London, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hristina","family":"Vasileva","sequence":"additional","affiliation":[{"name":"1Clinical Research Department, London School of Hygiene and Tropical Medicine, London, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Mabey","sequence":"additional","affiliation":[{"name":"1Clinical Research Department, London School of Hygiene and Tropical Medicine, London, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Last","sequence":"additional","affiliation":[{"name":"1Clinical Research Department, London School of Hygiene and Tropical Medicine, London, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/104\/6\/article-p2117.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/104\/6\/article-p2117.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T16:40:05Z","timestamp":1622652005000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/104\/6\/article-p2117.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,2]]},"references-count":0,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.20-1029","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,2]]}}}