{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T01:57:54Z","timestamp":1791424674277,"version":"4.3.3"},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,7,7]]},"abstract":"<jats:title>Abstract.<\/jats:title><jats:p>The presence of intestinal pathogenic <jats:italic>Escherichia coli<\/jats:italic> in drinking water is well recognized as a risk for diarrhea. The role of drinking water in extraintestinal infections caused by <jats:italic>E. coli<\/jats:italic>\u2014such as urinary tract infections (UTIs)\u2014remains poorly understood. Urinary tract infections are a leading cause of outpatient infections globally, with a lifetime incidence of 50\u201360% in adult women. We reviewed the scientific literature on the occurrence of uropathogenic <jats:italic>E. coli<\/jats:italic> (UPEC) in water supplies to determine whether the waterborne route may be an important, overlooked, source of UPEC. A limited number of studies have assessed whether UPEC isolates are present in drinking water supplies, but no studies have measured whether their presence in water may increase UPEC colonization or the risk of UTIs in humans. Given the prevalence of drinking water supplies contaminated with <jats:italic>E. coli<\/jats:italic> across the globe, efforts should be made to characterize UTI-related risks associated with drinking water, as well as other pathways of exposure.<\/jats:p>","DOI":"10.4269\/ajtmh.20-1271","type":"journal-article","created":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T14:31:25Z","timestamp":1620052285000},"page":"12-17","source":"Crossref","is-referenced-by-count":19,"title":["Waterborne Urinary Tract Infections: Have We Overlooked an Important Source of Exposure?"],"prefix":"10.4269","volume":"105","author":[{"given":"Jay P.","family":"Graham","sequence":"first","affiliation":[{"name":"1Berkeley School of Public Health, University of California Berkeley, Berkeley, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather K.","family":"Amato","sequence":"additional","affiliation":[{"name":"1Berkeley School of Public Health, University of California Berkeley, Berkeley, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata","family":"Mendizabal-Cabrera","sequence":"additional","affiliation":[{"name":"2Center for Health Studies, Universidad del Valle de Guatemala, Guatemala City, Guatemala;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danilo","family":"Alvarez","sequence":"additional","affiliation":[{"name":"2Center for Health Studies, Universidad del Valle de Guatemala, Guatemala City, Guatemala;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brooke M.","family":"Ramay","sequence":"additional","affiliation":[{"name":"2Center for Health Studies, Universidad del Valle de Guatemala, Guatemala City, Guatemala;"},{"name":"3Paul G. Allen School for Global Animal Health, Washington State University Pullman, Guatemala City, Guatemala"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/105\/1\/article-p12.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/105\/1\/article-p12.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T15:39:32Z","timestamp":1625758772000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/105\/1\/article-p12.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,7]]},"references-count":0,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.20-1271","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,7]]}}}