{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T08:50:54Z","timestamp":1765961454563},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,11,3]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Sporotrichosis is usually a subcutaneous infection caused by thermodimorphic fungi of the genus <jats:italic>Sporothrix<\/jats:italic>. The disease occurs worldwide, but endemic areas are located in tropical and subtropical regions. The epidemiology of sporotrichosis in Brazil is peculiar because of the cat\u2019s entry in the chain of transmission of this mycosis, associated with <jats:italic>Sporothrix brasiliensis<\/jats:italic>, the most virulent species in the genus. Sinusitis caused by <jats:italic>Sporothrix<\/jats:italic> species is unusual and may be underdiagnosed or confused with other fungal etiologies, like mucormycosis. We report a case of sinusitis due to a <jats:italic>Sporothrix<\/jats:italic> species in a 6-year renal transplant recipient. Direct examination of smears of exudate of the sinus specimen (aspirate, biopsy) revealed budding yeasts and cigar-shaped cells. <jats:italic>Sporothrix<\/jats:italic> was subsequently recovered from the patient\u2019s exudate culture and identified as <jats:italic>S. brasiliensis<\/jats:italic> using species-specific polymerase chain reaction, and she was successfully treated with antifungal therapy. Her parents also developed the disease a week later, both only cutaneous involvement. Sporotrichosis sinusitis is a rare disease, even in immunocompromised patients. Diagnosis is crucial, and benefits from good epidemiological history.<\/jats:p>","DOI":"10.4269\/ajtmh.20-1602","type":"journal-article","created":{"date-parts":[[2021,9,20]],"date-time":"2021-09-20T14:21:09Z","timestamp":1632147669000},"page":"1218-1221","source":"Crossref","is-referenced-by-count":7,"title":["Case Report: Invasive Sinusitis due to Sporothrix Brasiliensis in a Renal Transplant Recipient"],"prefix":"10.4269","volume":"105","author":[{"given":"Maria J\u00falia Correia Lima","family":"Nepomuceno Ara\u00fajo","sequence":"first","affiliation":[{"name":"1Hospital Nove de Julho, S\u00e3o Paulo, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila Hitome","family":"Nihei","sequence":"additional","affiliation":[{"name":"1Hospital Nove de Julho, S\u00e3o Paulo, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anderson Messias","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"2Laboratory of Emerging Fungal Pathogens, Department of Microbiology, Immunology, and Parasitology, Discipline of Cellular Biology, Federal University of S\u00e3o Paulo (UNIFESP), S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hermes","family":"Higashino","sequence":"additional","affiliation":[{"name":"1Hospital Nove de Julho, S\u00e3o Paulo, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vinicius","family":"Ponzio","sequence":"additional","affiliation":[{"name":"1Hospital Nove de Julho, S\u00e3o Paulo, Brazil;"},{"name":"2Laboratory of Emerging Fungal Pathogens, Department of Microbiology, Immunology, and Parasitology, Discipline of Cellular Biology, Federal University of S\u00e3o Paulo (UNIFESP), S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Carlos","family":"Campos Pignatari","sequence":"additional","affiliation":[{"name":"1Hospital Nove de Julho, S\u00e3o Paulo, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Alice","family":"Barcellos","sequence":"additional","affiliation":[{"name":"1Hospital Nove de Julho, S\u00e3o Paulo, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osni","family":"Braga","sequence":"additional","affiliation":[{"name":"1Hospital Nove de Julho, S\u00e3o Paulo, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene Faria","family":"Duayer","sequence":"additional","affiliation":[{"name":"1Hospital Nove de Julho, S\u00e3o Paulo, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/105\/5\/article-p1218.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/105\/5\/article-p1218.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T14:32:53Z","timestamp":1635949973000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/105\/5\/article-p1218.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,3]]},"references-count":0,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.20-1602","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,3]]}}}