{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T08:03:11Z","timestamp":1774598591048,"version":"3.50.1"},"reference-count":19,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,1]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p><jats:italic>Anopheles darlingi<\/jats:italic> is the main vector of malaria in South America. In French Guiana, malaria transmission occurs inland and along the rivers with a regular reemergence in the lower Oyapock area. Control against malaria vectors includes indoor residual spraying of deltamethrin and the distribution of long-lasting impregnated bednets. In this context, the level of resistance to pyrethroids was monitored for 4 years using CDC bottle tests in <jats:italic>An. darlingi<\/jats:italic> populations. A loss of susceptibility to pyrethroids was recorded with 30-minute knock-down measured as low as 81%. However, no pyrethroid molecular resistance was found by sequencing a 170 base pair fragment of the S6 segment of domain II of the voltage-gated sodium channel gene. Fluctuation of resistance phenotypes may be influenced by the reintroduction of susceptible alleles from sylvatic populations or by other mechanisms of metabolic resistance.<\/jats:p>","DOI":"10.4269\/ajtmh.20-1611","type":"journal-article","created":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T13:08:19Z","timestamp":1671455299000},"page":"424-427","source":"Crossref","is-referenced-by-count":4,"title":["Variation in Pyrethroid Resistance Phenotypes in Anopheles darlingi in an Area with Residual Malaria Transmission: Warning of Suspected Resistance in French Guiana"],"prefix":"10.4269","volume":"108","author":[{"given":"Samuel","family":"Vezenegho","sequence":"first","affiliation":[{"name":"Institut Pasteur de la Guyane, Vectop\u00f4le Amazonien Emile Abonnenc, Cayenne, French Guiana, France;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romuald","family":"Carinci","sequence":"additional","affiliation":[{"name":"Institut Pasteur de la Guyane, Vectop\u00f4le 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