{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T10:36:35Z","timestamp":1778754995750,"version":"3.51.4"},"reference-count":16,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Trop Med Hyg"],"published-print":{"date-parts":[[2003,5]]},"abstract":"<jats:p>Dermatologic manifestations are quite common in patients with adult T cell leukemia\/lymphoma and myelopathy\/tropical spastic paraparesis associated with infection with human T cell lymphotropic virus type-1 (HTLV-1). In this study, we evaluated the dermatologic lesions of eligible blood donors in the state of Minas Gerais in Brazil who were seropositive but asymptomatic for infection with HTLV-1. The study population was composed of 128 HTLV-1-seropositive individuals and 108 seronegative controls. All individuals underwent a dermatologic evaluation. Biopsy specimens were obtained from abnormal and normal skin samples of seropositive individuals in an attempt to detect HTLV-1 in tissue samples by a polymerase chain reaction. Dermatologic alterations were observed more frequently in the seropositive group (adjusted odds ratio [OR] = 8.77, 95% confidence interval [CI] = 4.11\u201318.71). The most common skin diseases were dermatophytoses (adjusted OR = 3.32, 95% CI = 1.50\u20137.35), seborrheic dermatitis (OR = 3.53, 95% CI = 0.67\u201324.66), and acquired ichthyosis (<jats:italic>P<\/jats:italic> = 0.001). Virus was detected more frequently in abnormal skin samples. Dermatologic lesions probably related to HTLV-1 infection were diagnosed in eligible blood donors who were infected with this virus, who were previously considered to be asymptomatic carriers of HTLV-1.<\/jats:p>","DOI":"10.4269\/ajtmh.2003.68.562","type":"journal-article","created":{"date-parts":[[2017,5,10]],"date-time":"2017-05-10T17:38:51Z","timestamp":1494437931000},"page":"562-565","source":"Crossref","is-referenced-by-count":45,"title":["DERMATOLOGIC LESIONS IN ASYMPTOMATIC BLOOD DONORS SEROPOSITIVE FOR HUMAN T CELL LYMPHOTROPIC VIRUS TYPE-1"],"prefix":"10.4269","volume":"68","author":[{"given":"DENISE UTSCH","family":"GONC\u0327ALVES","sequence":"first","affiliation":[{"name":"Departments of Internal Medicine and Basic Sciences Institute, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Minas Gerais State Center of Hematology and Hemotherapy, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ANTO\u0302NIO CARLOS MARTINS","family":"GUEDES","sequence":"additional","affiliation":[{"name":"Departments of Internal Medicine and Basic Sciences Institute, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Minas Gerais State Center of Hematology and Hemotherapy, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ANNA BA\u0301RBARA","family":"DE FREITAS CARNEIRO PROIETTI","sequence":"additional","affiliation":[{"name":"Departments of Internal Medicine and Basic Sciences Institute, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Minas Gerais State Center of Hematology and Hemotherapy, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MARINA LOBATO","family":"MARTINS","sequence":"additional","affiliation":[{"name":"Departments of Internal Medicine and Basic Sciences Institute, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Minas Gerais State Center of Hematology and Hemotherapy, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"FERNANDO AUGUSTO","family":"PROIETTI","sequence":"additional","affiliation":[{"name":"Departments of Internal Medicine and Basic Sciences Institute, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Minas Gerais State Center of Hematology and Hemotherapy, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JOSE\u0301 ROBERTO","family":"LAMBERTUCCI","sequence":"additional","affiliation":[{"name":"Departments of Internal Medicine and Basic Sciences Institute, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Minas Gerais State Center of Hematology and Hemotherapy, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"_","family":"_","sequence":"additional","affiliation":[{"name":"Departments of Internal Medicine and Basic Sciences Institute, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Minas Gerais State Center of Hematology and Hemotherapy, Belo Horizonte, Minas Gerais, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Proc Natl Acad Sci USA","first-page":"2534","volume":"81","year":"1984"},{"key":"R2","series-title":"Lancet","first-page":"651","volume":"1","year":"1988"},{"key":"R3","year":"1989"},{"key":"R4","series-title":"Arch Dermatol","first-page":"439","volume":"134","year":"1998"},{"key":"R5","series-title":"Br J Dermatol","first-page":"137","volume":"138","year":"1998"},{"key":"R6","series-title":"Nucleic Acids Res","first-page":"4293","volume":"19","year":"1991"},{"key":"R7","series-title":"Science","first-page":"1117","volume":"72","year":"1988"},{"key":"R8","series-title":"Electrophoresis","first-page":"1041","volume":"12","year":"1991"},{"key":"R9","series-title":"Vox Sang","first-page":"77","volume":"67","year":"1994"},{"key":"R10","series-title":"Am J Epidemiol","first-page":"1114","volume":"133","year":"1991"},{"key":"R11","series-title":"J Exp Med","first-page":"1581","volume":"180","year":"1994"},{"key":"R12","series-title":"Jpn J Cancer Res","first-page":"639","volume":"78","year":"1987"},{"key":"R13","series-title":"Int J STD AIDS","first-page":"336","volume":"10","year":"1999"},{"key":"R14","series-title":"Am J Pathol","first-page":"683","volume":"152","year":"1998"},{"key":"R15","series-title":"Br J Haematol","first-page":"169","volume":"68","year":"1988"},{"key":"R16","series-title":"Blood","first-page":"3080","volume":"84","year":"1994"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/68\/5\/article-p562.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/68\/5\/article-p562.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/68\/5\/article-p562.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T16:51:18Z","timestamp":1725382278000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/68\/5\/article-p562.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,5]]},"references-count":16,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.2003.68.562","relation":{},"ISSN":["0002-9637"],"issn-type":[{"value":"0002-9637","type":"print"}],"subject":[],"published":{"date-parts":[[2003,5]]}}}