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In this paper, the case for using laboratory assays to guide trachoma control strategies is presented, molecular methods for diagnosis (such as a ligase chain reaction and a polymerase chain reaction [PCR]) are compared with earlier techniques, and recent findings of ongoing studies using a quantitative PCR are reviewed. In addition, the contribution of genotyping to our understanding of the epidemiology and biology of <jats:italic>C. trachomatis<\/jats:italic> is considered.<\/jats:p>","DOI":"10.4269\/ajtmh.2003.69.11","type":"journal-article","created":{"date-parts":[[2017,5,10]],"date-time":"2017-05-10T16:37:41Z","timestamp":1494434261000},"page":"11-17","source":"Crossref","is-referenced-by-count":14,"title":["APPLICATION OF MOLECULAR TOOLS IN THE CONTROL OF BLINDING TRACHOMA"],"prefix":"10.4269","volume":"69","author":[{"given":"DAVID","family":"MABEY","sequence":"first","affiliation":[{"name":"Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ANTHONY W.","family":"SOLOMON","sequence":"additional","affiliation":[{"name":"Clinical Research Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, 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