{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T03:53:47Z","timestamp":1791172427618,"version":"4.1.0"},"reference-count":33,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,4]]},"abstract":"<jats:p>To elucidate the importance of the norovirus and other enteric viruses, and the difference of the genetic relatedness on norovirus between the outbreak and sporadic cases, a total of 557 stool samples, consisting of 503 sporadic cases and 54 samples of 4 outbreaks were collected and tested for norovirus and other enteric viruses in Beijing, China, July 2007\u2013June 2008. The data showed norovirus, rotavirus, astrovirus, and sapovirus, were detected in 26.6%, 6.1%, 1.8%, and 0.5%, respectively. Norovirus was detected almost throughout the surveillance period, norovirus co-infecting with rotavirus, astrovirus, and sapovirus, respectively, were identified both in outbreak and the sporadic cases. GII.4\/2006 was identified as the predominant strain circulating both in outbreak and sporadic cases. The results showed that norovirus was rather the important agent than other enteric viruses affected adults with acute gastroenteritis; no significant genetic relatedness of the dominant strains was found between the outbreak and sporadic cases.<\/jats:p>","DOI":"10.4269\/ajtmh.2010.09-0491","type":"journal-article","created":{"date-parts":[[2010,3,26]],"date-time":"2010-03-26T23:33:07Z","timestamp":1269646387000},"page":"717-722","source":"Crossref","is-referenced-by-count":19,"title":["Identification of Norovirus as the Top Enteric Viruses Detected in Adult Cases with Acute Gastroenteritis"],"prefix":"10.4269","volume":"82","author":[{"given":"Li-Juan","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, People's Republic of China; Department of the Hospital Infection Management and Control, the General Hospital of PLA, Beijing, People's Republic of China; Diarrhea Clinic, Department of Emergency, General Hospital of PLA, Beijing, People's Republic of China; Department of Pathogenic Molecular Biology, Beijing Institute of Microbiology and Epidemiology..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, People's Republic of China; Department of the Hospital Infection Management and Control, the General Hospital of PLA, Beijing, People's Republic of China; Diarrhea Clinic, Department of Emergency, General Hospital of PLA, Beijing, People's Republic of China; Department of Pathogenic Molecular Biology, Beijing Institute of Microbiology and Epidemiology..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun-Xi","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, People's Republic of China; Department of the Hospital Infection Management and Control, the General Hospital of PLA, Beijing, People's Republic of China; Diarrhea Clinic, Department of Emergency, General Hospital of PLA, Beijing, People's Republic of China; Department of Pathogenic Molecular Biology, Beijing Institute of Microbiology and Epidemiology..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Jv","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, People's Republic of China; Department of the Hospital Infection Management and Control, the General Hospital of PLA, Beijing, People's Republic of China; Diarrhea Clinic, Department of Emergency, General Hospital of PLA, Beijing, People's Republic of China; Department of Pathogenic Molecular Biology, Beijing Institute of Microbiology and Epidemiology..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Jia","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, People's Republic of China; Department of the Hospital Infection Management and Control, the General Hospital of PLA, Beijing, People's Republic of China; Diarrhea Clinic, Department of Emergency, General Hospital of PLA, Beijing, People's Republic of China; Department of Pathogenic Molecular Biology, Beijing Institute of Microbiology and Epidemiology..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, People's Republic of China; Department of the Hospital Infection Management and Control, the General Hospital of PLA, Beijing, People's Republic of China; Diarrhea Clinic, Department of Emergency, General Hospital of PLA, Beijing, People's Republic of China; Department of Pathogenic Molecular Biology, Beijing Institute of Microbiology and Epidemiology..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Gang","family":"Tong","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, People's Republic of China; Department of the Hospital Infection Management and Control, the General Hospital of PLA, Beijing, People's Republic of China; Diarrhea Clinic, Department of Emergency, General Hospital of PLA, Beijing, People's Republic of China; Department of Pathogenic Molecular Biology, Beijing Institute of Microbiology and Epidemiology..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu-Chun","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, People's Republic of China; Department of the Hospital Infection Management and Control, the General Hospital of PLA, Beijing, People's Republic of China; Diarrhea Clinic, Department of Emergency, General Hospital of PLA, Beijing, People's Republic of China; Department of Pathogenic Molecular Biology, Beijing Institute of Microbiology and Epidemiology..."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"R1","series-title":"J Infect Dis","first-page":"S262","article-title":"Molecular epidemiology of human enteric caliciviruses in The Netherlands","volume":"181","author":"Koopmans","year":"2000"},{"key":"R2","series-title":"MMWR Morb Mortal Wkly Rep","first-page":"842","article-title":"Norovirus activity\u2013United States, 2006\u20132007","volume":"56","author":"CDC","year":"2007"},{"key":"R3","series-title":"J Hosp Infect","first-page":"131","article-title":"Gastroenteritis outbreak with norovirus in a Swiss university hospital with a newly identified virus strain","volume":"55","author":"Khanna","year":"2003"},{"key":"R4","series-title":"J Am Geriatr Soc","first-page":"1839","article-title":"Norovirus outbreaks in nursing homes","volume":"53","author":"Drinka","year":"2005"},{"key":"R5","series-title":"Jpn J Infect Dis","first-page":"205","article-title":"A food-borne norovirus outbreak at a primary school in Wakayama prefecture","volume":"59","author":"Morioka","year":"2006"},{"key":"R6","series-title":"J Infect Dis","first-page":"1571","article-title":"Molecular epidemiology of \u201cNorwalk-like viruses\u201d in outbreaks of gastroenteritis in the United States","volume":"178","author":"Fankhauser","year":"1998"},{"key":"R7","series-title":"J Med Virol","first-page":"1703","article-title":"Molecular characterization of calicivirus strains detected in outbreaks of gastroenteritis in Argentina","volume":"79","author":"Gomes","year":"2007"},{"key":"R8","series-title":"Emerg Infect Dis","first-page":"607","article-title":"Food-related illness and deaths in the United State","volume":"5","author":"Mead","year":"1999"},{"key":"R9","series-title":"PLoS Med","first-page":"269","article-title":"Mechanisms of GII.4 norovirus persistence in human populations","volume":"5","author":"Lindesmith","year":"2008"},{"key":"R10","series-title":"J Med Virol","first-page":"1919","article-title":"Enteric viruses in pediatric diarrhea in Saudi Arabia","volume":"80","author":"Tayeb","year":"2008"},{"key":"R11","series-title":"J Pediatr","first-page":"339","article-title":"Outbreaks of necrotizing enterocolitis caused by norovirus in a neonatal intensive care unit","volume":"153","author":"Turcios-Ruiz","year":"2008"},{"key":"R12","author":"Ministry of Health of the People's Republic of China","year":"2009"},{"key":"R13","series-title":"J Med Virol","first-page":"1790","article-title":"Molecular characterization of enteric viral agents from children in northern region of Ghana","volume":"80","author":"Silva","year":"2008"},{"key":"R14","series-title":"J Med Virol","first-page":"1949","article-title":"Genetic diversity of norovirus, sapovirus, and astrovirus isolated from children hospitalized with acute gastroenteritis in Chiang Mai, Thailand","volume":"80","author":"Malasao","year":"2008"},{"key":"R15","series-title":"Emerg Infect Dis","first-page":"1244","article-title":"Norovirus detection and gentyping for children with gastroenteritis, Brazil","volume":"13","author":"Soares","year":"2007"},{"key":"R16","series-title":"J Infect Dis","first-page":"27","article-title":"Outbreaks of acute gastroenteritis on cruise ships and on land: identification of a predominant circulating strain of norovirus\u2013United States, 2002","volume":"190","author":"Widdowson","year":"2004"},{"key":"R17","series-title":"J Med Virol","first-page":"113","article-title":"Norwalk-like virus 95\/96-US, strain is a major cause of gastroenteritis outbreaks in Australia","volume":"68","author":"White","year":"2002"},{"key":"R18","series-title":"Lancet","first-page":"682","article-title":"Increase in viral gastroenteritis outbreak in Europe and epidemic spread of new norovirus variant","volume":"363","author":"Lopman","year":"2004"},{"key":"R19","series-title":"Clin Infect Dis","first-page":"413","article-title":"Epidemics of gastroenteritis during 2006 were associated with the spread of norovirus GII.4 variants 2006a and 2006b","volume":"46","author":"Tu","year":"2008"},{"key":"R20","series-title":"J Clin Virol","first-page":"168","article-title":"Multiplex real time RT-PCR for the detection and quantitation of norovirus genogroups I and II in patients with acute gastroenteritis","volume":"33","author":"Pang","year":"2005"},{"key":"R21","series-title":"J Clin Virol","first-page":"238","article-title":"Viral agents associated with acute gastroenteritis in children hospitalized with diarrhea in Lanzhou, China","volume":"44","author":"Jin","year":"2009"},{"key":"R22","series-title":"Clin Infect Dis","first-page":"849","article-title":"Norovirus infection as a cause of diarrhea-associated benign infantile seizures","volume":"48","author":"Chen","year":"2009"},{"key":"R23","series-title":"J Med Virol","first-page":"1997","article-title":"Emergence of the GII4\/2006 variant and recombinant noroviruses in China","volume":"80","author":"Jin","year":"2008"},{"key":"R24","series-title":"J Virol Methods","first-page":"37","article-title":"Detection of norovirus (GI,GII), Sapovirus and astrovirus in fecal samples using reverse transcription single-round multiplex PCR","volume":"114","author":"Yan","year":"2003"},{"key":"R25","series-title":"J Med Virol","first-page":"388","article-title":"Molecular detection and sequencing of \u201cNorwalk-like viruses\u201d in outbreaks and sporadic cases of gastroenteritis in Ireland","volume":"65","author":"Foley","year":"2001"},{"key":"R26","series-title":"Eur J Clin Microbiol Infect Dis","first-page":"311","article-title":"Detection by PCR of eight groups of enteric pathogens in 4,627 faecal samples: re-examination of the English case-control Infectious Intestinal Disease Study (1993\u20131996)","volume":"26","author":"Amar","year":"2007"},{"key":"R27","series-title":"J Med Virol","first-page":"307","article-title":"Surveillance of norovirus infection in a study of sporadic childhood gastroenteritis in South West England and South Wales, during one winter season (1999\u20132000)","volume":"72","author":"Froggatt","year":"2004"},{"key":"R28","series-title":"J Med Virol","first-page":"2161","article-title":"Prevalence and molecular epidemiology of noroviruses detected in outbreak and sporadic cases of acute gastroenteritis in Bulgaria","volume":"80","author":"Mladenova","year":"2008"},{"key":"R29","series-title":"J Infect Dis","first-page":"1","article-title":"Epidemiologic and molecular trends of \u201cNorwalk-like viruses\u201d associated with outbreaks of gastroenteritis in Unites States","volume":"186","author":"Fankhauser","year":"2002"},{"key":"R30","series-title":"J Med Virol","first-page":"330","article-title":"Genetic relatedness of noroviruses identified in sporadic gastroenteritis in children and gastroenteritis outbreaks in Northern Alberta","volume":"80","author":"Lee","year":"2008"},{"key":"R31","series-title":"Emerg Infect Dis","first-page":"857","article-title":"Novel recombinant norovirus in China","volume":"12","author":"Phan","year":"2006"},{"key":"R32","series-title":"J Clin Virol","first-page":"94","article-title":"Genetic analysis of norovirus in children affected with acute gastroenteritis in Beijing, 2004\u20132007","volume":"44","author":"Guo","year":"2009"},{"key":"R33","series-title":"Emerg Infect Dis","first-page":"1079","article-title":"Norovirus recombination in ORF1\/ORF2 overlap","volume":"11","author":"Bull","year":"2005"}],"container-title":["The American Society of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/82\/4\/article-p717.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/82\/4\/article-p717.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/82\/4\/article-p717.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,2]],"date-time":"2024-09-02T15:53:50Z","timestamp":1725292430000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/82\/4\/article-p717.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4]]},"references-count":33,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.2010.09-0491","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4]]}}}