{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T16:14:29Z","timestamp":1777652069486,"version":"3.51.4"},"reference-count":9,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,10,5]]},"abstract":"<jats:p>The aim of the present preliminary study was to investigate the potential of measurement of IFN-\u03b3 secretion by T cells into blood plasma using QuantiFERON assay with leishmanial antigens to determine the presence of <jats:italic>Leishmania<\/jats:italic> infection. Blood samples from cured visceral (<jats:italic>N<\/jats:italic> = 18), and cutaneous (<jats:italic>N<\/jats:italic> = 20) leishmaniasis cases, and 20 healthy controls were tested. The IFN-\u03b3 responses to <jats:italic>Leishmania major<\/jats:italic> H2B and <jats:italic>Leishmania infantum<\/jats:italic> H2B antigens were detected from the majority of treated old visceral leishmaniasis cases, but not from controls. Future studies using larger groups will be required to establish the true potential of the assay for epidemiological screening of leishmaniasis.<\/jats:p>","DOI":"10.4269\/ajtmh.2010.09-0605","type":"journal-article","created":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T17:15:08Z","timestamp":1285953308000},"page":"822-824","source":"Crossref","is-referenced-by-count":25,"title":["Quantiferon-Leishmania as an Epidemiological Tool for Evaluating the Exposure to Leishmania Infection"],"prefix":"10.4269","volume":"83","author":[{"given":"Nevin","family":"Turgay","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I. 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