{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T09:07:36Z","timestamp":1764493656823},"reference-count":9,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,1,5]]},"abstract":"<jats:p>We report the first case of visceral leishmaniasis (VL) from the non-endemic western hilly region of Nepal. The patient presented with a history of high-grade fever, abdominal distension, anemia, and weight loss. The case was confirmed as VL by microscopical detection of the <jats:italic>Leishmania<\/jats:italic> species amastigote in bone marrow aspiration and by a positive result for the rK39 test. The patient was treated with 0.5\u20131.0 mg\/kg of Amphotericin B for 14 days (total of 405 mg), and amastigotes were negative on discharge. Five months later, this patient again developed fever, abdominal distension, and anemia. Clinical and hematological examinations suggested a relapse of VL. The patient was treated with 1 mg\/kg of Amphotericin B for 18 days (total of 515 mg) and was clinically improved on discharge.<\/jats:p>","DOI":"10.4269\/ajtmh.2011.10-0291","type":"journal-article","created":{"date-parts":[[2011,1,6]],"date-time":"2011-01-06T16:27:08Z","timestamp":1294331228000},"page":"107-108","source":"Crossref","is-referenced-by-count":24,"title":["Expansion of Visceral Leishmaniasis to the Western Hilly Part of Nepal"],"prefix":"10.4269","volume":"84","author":[{"given":"Basu Dev","family":"Pandey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sher Bahadur","family":"Pun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Kaneko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kishor","family":"Pandey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Hirayama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Parasitol Res","first-page":"293","article-title":"Molecular detection of Leishmania parasites from whole bodies of sandflies collected in Nepal","volume":"108","author":"Pandey","year":"2008"},{"year":"2005","series-title":"Regional technical advisory group on kala-azar elimination","author":"World Health Organization","key":"R2"},{"key":"R3","series-title":"Annual Report on Nepal","first-page":"145","author":"Department of Health Sciences","year":"2007"},{"key":"R4","series-title":"Trans R Soc Trop Med Hyg","first-page":"350","article-title":"Treatment of visceral leishmaniasis in south-eastern Nepal: decreasing efficacy of sodium stiboglucanate and need for the policy to limit further decline","volume":"97","author":"Rijal","year":"2003"},{"key":"R5","series-title":"Kathmandu Univ Med J","first-page":"232","article-title":"Kala-azar (visceral leishmaniasis) from Khotang","volume":"4","author":"Joshi","year":"2006"},{"key":"R6","series-title":"Park's Text Book of Preventive and Social Medicine","first-page":"256","author":"Park","year":"2007"},{"key":"R7","series-title":"Trans R Soc Trop Med Hyg","first-page":"730","article-title":"Sodium stibogluconate-sensitive visceral leishmaniasis in the non-endemic hilly region of Uttarkhand, India","volume":"101","author":"Verma","year":"2007"},{"key":"R8","series-title":"J Commun Dis","first-page":"117","article-title":"Kala-azar at high altitude","volume":"36","author":"Mahajan","year":"2004"},{"key":"R9","series-title":"Am J Trop Med Hyg","first-page":"580","article-title":"Relapse of visceral leishmaniasis after miltefosine treatment in a Nepalese patient","volume":"80","author":"Pandey","year":"2009"}],"container-title":["The American Society of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/84\/1\/article-p107.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/84\/1\/article-p107.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/84\/1\/article-p107.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T20:07:19Z","timestamp":1723061239000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/84\/1\/article-p107.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1,5]]},"references-count":9,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.2011.10-0291","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"type":"print","value":"0002-9637"},{"type":"electronic","value":"1476-1645"}],"subject":[],"published":{"date-parts":[[2011,1,5]]}}}