{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T04:10:15Z","timestamp":1777954215185,"version":"3.51.4"},"reference-count":48,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,12,1]]},"abstract":"<jats:p>We report our experience in managing 13 consecutive clinically suspected cases of Buruli ulcer on the face treated at the hospital of the Institut M\u00e9dical Evang\u00e9lique at Kimpese, Democratic Republic of Congo diagnosed during 2003\u20132007. During specific antibiotherapy, facial edema diminished, thus minimizing the subsequent extent of surgery and severe disfigurations. The following complications were observed: 1) lagophthalmos from scarring in four patients and associated ectropion in three of them; 2) blindness in one eye in one patient; 3) disfiguring exposure of teeth and gums resulting from excision of the left labial commissure that affected speech, drinking, and eating in one patient; and 4) dissemination of <jats:italic>Mycobacterium ulcerans<\/jats:italic> infection in three patients. Our study highlights the importance of this clinical presentation of Buruli ulcer, and the need for health workers in disease-endemic areas to be aware of the special challenges management of Buruli ulcer on the face presents.<\/jats:p>","DOI":"10.4269\/ajtmh.2011.10-0530","type":"journal-article","created":{"date-parts":[[2011,12,5]],"date-time":"2011-12-05T18:05:03Z","timestamp":1323108303000},"page":"1100-1105","source":"Crossref","is-referenced-by-count":10,"title":["Mycobacterium ulcerans Infection (Buruli Ulcer) on the Face: A Comparative Analysis of 13 Clinically Suspected Cases from the Democratic Republic of Congo"],"prefix":"10.4269","volume":"85","author":[{"given":"Delphin M.","family":"Phanzu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger L.","family":"Mahema","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Suykerbuyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D\u00e9sir\u00e9-Hubert B.","family":"Imposo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda F.","family":"Lehman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elie","family":"Nduwamahoro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wayne M.","family":"Meyers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marleen","family":"Boelaert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7oise","family":"Portaels","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Clin Dermatol","first-page":"291","article-title":"Buruli ulcer","volume":"27","author":"Portaels","year":"2009"},{"key":"R2","series-title":"Buruli Ulcer-Mycobacterium ulcerans Infection","author":"World Health Organization","year":"2000"},{"key":"R3","series-title":"Wkly Epidemiol Rec","first-page":"194","article-title":"Buruli ulcer disease. Mycobacterium ulcerans infection: an overview of reported cases globally","volume":"79","author":"World Health Organization","year":"2004"},{"key":"R4","series-title":"Buruli Ulcer. Diagnosis of Mycobacterium ulcerans Disease","author":"World Health Organization","year":"2001"},{"key":"R5","series-title":"Bull Seances Acad R Sci Outre Mer","first-page":"265","article-title":"Buruli ulcer: a historical overview with updating to 2005","volume":"51","author":"Janssens","year":"2005"},{"key":"R6","series-title":"Rev Stomatol Chir Maxillofac","first-page":"231","article-title":"Les localisations faciales de l'ulc\u00e8re de Buruli: \u00e0 propos de deux cas","volume":"104","author":"Ouattara","year":"2003"},{"key":"R7","series-title":"Med Trop (Mars)","first-page":"643","article-title":"Ulc\u00e8re de Buruli c\u00e9phalique: huit observations au CHU d'Abidjan, C\u00f4te d'Ivoire","volume":"68","author":"Kouame","year":"2008"},{"key":"R8","series-title":"Am J Trop Med Hyg","first-page":"520","article-title":"Buruli ulcer disease in Cameroon rediscovered","volume":"70","author":"Noeske","year":"2004"},{"key":"R9","series-title":"Trop Med Int 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transport medium","volume":"46","author":"Eddyani","year":"2008"},{"key":"R14","series-title":"Am J Trop Med Hyg","first-page":"311","article-title":"Mycobacterium ulcerans disease (Buruli ulcer) in a rural hospital in Bas-Congo, Democratic Republic of Congo, 2002\u20132004","volume":"75","author":"Phanzu","year":"2006"},{"key":"R15","series-title":"J Clin Microbiol","first-page":"1700","article-title":"Fine-needle aspiration, an efficient sampling technique for bacteriological diagnosis of nonulcerative Buruli ulcer","volume":"47","author":"Eddyani","year":"2009"},{"key":"R16","series-title":"Emerg Infect Dis","first-page":"1374","article-title":"Buruli ulcer surveillance, Benin, 2003\u20132005","volume":"13","author":"Sopoh","year":"2007"},{"key":"R17","series-title":"Trop Doct","first-page":"82","article-title":"Buruli ulcer in the Democratic Republic of Congo: epidemiology, presentation and outcome","volume":"34","author":"Bafende","year":"2004"},{"key":"R18","series-title":"Ann 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