{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T17:50:10Z","timestamp":1788198610111,"version":"build-2803163510"},"reference-count":33,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,9,1]]},"abstract":"<jats:p>Trachoma control strategies, including latrine construction and antibiotic distribution, are directed at reducing ocular <jats:italic>chlamydia<\/jats:italic>, but may have additional benefits. In a cluster-randomized clinical trial, 24 subkebeles (administrative geographic units) in Ethiopia were offered a single mass azithromycin treatment, and half were randomized to receive an intensive latrine promotion. At a follow-up census 26 months after the baseline treatment, 320 persons had died. The mortality rate of children 1\u20135 years of age was 3.87 (95% confidence interval [CI] = 2.19\u20136.82) per 1,000 person-years in the latrine promotion arm, and 2.72 (95% CI = 1.37\u20135.42) per 1,000 person-years in the control arm. In a multi-level mixed effects logistic regression model controlling for age, there was no difference in mortality in persons randomized into the latrine or control arms (odds ratio = 1.18, 95% CI = 0.89\u20131.58). Latrine promotion provided no additional effect on mortality in the context of an azithromycin distribution program (clinicaltrials.gov, #NCT00322972).<\/jats:p>","DOI":"10.4269\/ajtmh.2011.10-0720","type":"journal-article","created":{"date-parts":[[2011,9,6]],"date-time":"2011-09-06T18:47:57Z","timestamp":1315334877000},"page":"518-523","source":"Crossref","is-referenced-by-count":17,"title":["Latrine Promotion for Trachoma: Assessment of Mortality from a Cluster-Randomized Trial in Ethiopia"],"prefix":"10.4269","volume":"85","author":[{"given":"Teshome","family":"Gebre","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berhan","family":"Ayele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mulat","family":"Zerihun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenafir 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