{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T04:05:28Z","timestamp":1782878728810,"version":"3.54.5"},"reference-count":14,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,7,1]]},"abstract":"<jats:p><jats:italic>Burkholderia pseudomallei<\/jats:italic>, the causative agent of melioidosis, is endemic in northeastern Thailand. Population-based disease burden estimates are lacking and limited data on melioidosis exist from other regions of the country. Using active, population-based surveillance, we measured the incidence of bacteremic melioidosis in the provinces of Sa Kaeo (eastern Thailand) and Nakhon Phanom (northeastern Thailand) during 2006\u20132008. The average annual incidence in Sa Kaeo and Nakhon Phanom per 100,000 persons was 4.9 (95% confidence interval [CI] = 3.9\u20136.1) and 14.9 (95% CI = 13.3\u201316.6). The respective population mortality rates were 1.9 (95% CI = 1.3\u20132.8) and 4.4 (95% CI = 3.6\u20135.3) per 100,000. The case-fatality proportion was 36% among those with known outcome. Our findings document a high incidence and case fatality proportion of bacteremic melioidosis in Thailand, including a region not traditionally considered highly endemic, and have potential implications for clinical management and health policy.<\/jats:p>","DOI":"10.4269\/ajtmh.2011.11-0070","type":"journal-article","created":{"date-parts":[[2011,7,6]],"date-time":"2011-07-06T18:34:20Z","timestamp":1309977260000},"page":"117-120","source":"Crossref","is-referenced-by-count":24,"title":["Incidence of Bacteremic Melioidosis in Eastern and Northeastern Thailand"],"prefix":"10.4269","volume":"85","author":[{"given":"Saithip","family":"Bhengsri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry 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F.","family":"Peruski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan A.","family":"Maloney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Clin Microbiol Rev","first-page":"52","article-title":"Melioidosis: the tip of the iceberg?","volume":"4","author":"Dance","year":"1991"},{"key":"R2","series-title":"Annual Epidemiology Surveillance Report","author":"Bureau of Epidemiology, Ministry of Public Health, Thailand","year":"2009"},{"key":"R3","series-title":"Int J Epidemiol","first-page":"1082","article-title":"The epidemiology of melioidosis in Ubon Ratchatani, northeast Thailand","volume":"23","author":"Suputtamongkol","year":"1994"},{"key":"R4","series-title":"J Health Sci","first-page":"363","article-title":"Monthly rainfall and severity of melioidosis in Nakhon Phanom, northeastern 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melioidosis","volume":"36","author":"Sookpranee","year":"1992"},{"key":"R9","series-title":"Epidemiol Infect","first-page":"1811","article-title":"Incidence of respiratory pathogens in persons hospitalized with pneumonia in two provinces in Thailand","volume":"138","author":"Olsen","year":"2010"},{"key":"R10","series-title":"J Infect Dis Antimicrob Agents","first-page":"45","article-title":"Melioidosis at Maharaj Nakorn Chiang Mai Hospital, Thailand","volume":"22","author":"Chaiwarith","year":"2005"},{"key":"R11","series-title":"J Infect Dis Antimicrob Agents","first-page":"1","article-title":"Epidemiology and clinical outcome of melioidosis at Chonburi Hospital, Thailand","volume":"25","author":"Waiwarawooth","year":"2007"},{"issue":"(Suppl 2)","key":"R12","series-title":"Clin Infect Dis","first-page":"S65","article-title":"Incidence of pneumococcal bacteremia requiring hospitalization in rural Thailand","volume":"48","author":"Baggett","year":"2009"},{"key":"R13","series-title":"Population Projection for Thailand, 2000\u20132030","author":"Office of the National Economic and Social Development Board","year":"2007"},{"key":"R14","series-title":"Clin Microbiol Rev","first-page":"383","article-title":"Melioidosis: epidemiology, pathophysiology, and management","volume":"18","author":"Cheng","year":"2005"}],"container-title":["The American Society of Tropical Medicine and 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