{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:01:20Z","timestamp":1791849680017,"version":"4.3.4"},"reference-count":36,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,1,1]]},"abstract":"<jats:p>We conducted a prospective, inpatient fever study in malaria-endemic Papua, Indonesia to determine non-malaria fever etiologies. Investigations included malaria blood films, blood culture, paired serologic samples analysis for dengue, Japanese encephalitis, leptospirosis, scrub typhus, murine typhus, and spotted fever group rickettsia. During 1997\u20132000, 226 patients (127 males and 99 females) 1\u201380 years of age (median age = 25 years) were enrolled. Positive blood cultures (n = 34, 15%) were obtained for <jats:italic>Salmonella<\/jats:italic> Typhi (n = 13), <jats:italic>Escherichia coli<\/jats:italic> (n = 8), <jats:italic>Streptococcus pneumoniae<\/jats:italic> (n = 6), <jats:italic>Staphylococcus aureus<\/jats:italic> (n = 5), <jats:italic>Streptococcus pyogenes<\/jats:italic> (n = 1), and <jats:italic>Klebsiella pneumoniae<\/jats:italic> (n = 1). Twenty (8.8%) patients were positive for leptospirosis by polymerase chain reaction. Eighty (35.4%) of 226 patients had \u2265 1 positive serology, diagnostic for 15 rickettsial and 9 dengue cases. Acid-fast bacilli\u2013positive sputum was obtained from three patients. Most common confirmed (81 of 226, 35.8%)\/suspected diagnoses were typhoid fever (n = 41), pneumonia (n = 29), leptospirosis (n = 28), urinary tract infections (n = 20), rickettsioses (n = 19), dengue (n = 17), and meningitis\/encephalitis (n = 15). There were 17 deaths, 7 (46.7%) were caused by meningitis\/encephalitis. Multiple positive serologic results and few confirmed diagnoses indicate the need for improved diagnostics.<\/jats:p>","DOI":"10.4269\/ajtmh.2012.10-0497","type":"journal-article","created":{"date-parts":[[2012,1,9]],"date-time":"2012-01-09T22:56:40Z","timestamp":1326149800000},"page":"46-51","source":"Crossref","is-referenced-by-count":61,"title":["Etiology of Acute, Non-Malaria, Febrile Illnesses in Jayapura, Northeastern Papua, Indonesia"],"prefix":"10.4269","volume":"86","author":[{"given":"Narain H.","family":"Punjabi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter R. 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