{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T12:36:16Z","timestamp":1758630976773},"reference-count":39,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,6,1]]},"abstract":"<jats:p>The purpose of this study was to describe the brain magnetic resonance imaging (MRI) findings in young patients with hepatosplenic schistosomiasis mansoni without overt neurologic manifestations. This study included 34 young persons (age range = 9\u201325 years) with hepatosplenic schistosomiasis mansoni who had been previously treated. Patients were scanned on a 1.5-T system that included multiplanar pre-contrast and post-contrast sequences, and reports were completed by two radiologists after a consensus review. Twenty (58.8%) patients had MRI signal changes that were believed to be related to schistosomiasis mansoni. Twelve of the 20 patients had small focal hyperintensities on T2WI in the cerebral white matter, and eight patients had symmetric hyperintense basal ganglia on T1WI. There was a high frequency of brain MRI signal abnormalities in this series. Although not specific, these findings may be related to schistosomiasis.<\/jats:p>","DOI":"10.4269\/ajtmh.2012.11-0419","type":"journal-article","created":{"date-parts":[[2012,6,4]],"date-time":"2012-06-04T20:16:06Z","timestamp":1338840966000},"page":"982-987","source":"Crossref","is-referenced-by-count":18,"title":["Brain Magnetic Resonance Imaging Findings in Young Patients with Hepatosplenic Schistosomiasis Mansoni without Overt Symptoms"],"prefix":"10.4269","volume":"86","author":[{"given":"Adonis","family":"Manzella","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"Borba-Filho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos T.","family":"Brandt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keyla","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Mem Inst Oswaldo Cruz","first-page":"13","article-title":"Epidemiological and control aspects of schistosomiasis in Brazilian endemic areas","volume":"99","author":"Coura","year":"2004"},{"key":"R2","series-title":"Am J Trop Med Hyg","first-page":"294","article-title":"Antibodies to Schistosoma mansoni in human cerebrospinal fluid","volume":"68","author":"Magalh\u00e3es-Santos","year":"2003"},{"key":"R3","series-title":"Brain Pathol","first-page":"649","article-title":"Neuroschistosomiasis","volume":"7","author":"Pittella","year":"1997"},{"key":"R4","series-title":"Arch Neurol","first-page":"1008","article-title":"Seizures and cerebral schistosomiasis","volume":"62","author":"Betting","year":"2005"},{"key":"R5","series-title":"Arq Neuropsiquiatr","first-page":"353","article-title":"Clinical and cerebrospinal fluid (CSF) profile and CSF criteria for the diagnosis of spinal cord schistosomiasis","volume":"61","author":"Carvalho","year":"2003"},{"key":"R6","series-title":"Rev Hosp Clin Fac Med Sao Paulo","first-page":"10","article-title":"Portal hyperflow in patients with hepatosplenic mansonic schistosomiasis","volume":"59","author":"Cleva","year":"2004"},{"key":"R7","series-title":"Brain","first-page":"621","article-title":"Brain involvement in hepatosplenic schistosomiasis mansoni","volume":"104","author":"Pittella","year":"1981"},{"key":"R8","series-title":"Mem Inst Oswaldo Cruz","first-page":"59","article-title":"Involvement of central nervous system in the schistosomiasis","volume":"99","author":"Ferrari","year":"2004"},{"key":"R9","series-title":"Clin Neurol Neurosurg","first-page":"15","article-title":"Tumoral form of cerebral schistosomiasis mansoni: a report of cases and a review of the literature","volume":"98","author":"Pittella","year":"1996"},{"key":"R10","series-title":"Br J Neurosurg","first-page":"239","article-title":"Neuroschistosomiasis myelopathy: case report","volume":"8","author":"Shail","year":"1994"},{"key":"R11","series-title":"J Neurosurg","first-page":"1065","article-title":"Schistosoma mansoni infection involving the spinal cord: case report","volume":"82","author":"Ueki","year":"1995"},{"key":"R12","series-title":"Eur J Radiol","first-page":"268","article-title":"Schistosomal myelitis: findings at MR imaging","volume":"27","author":"Bennett","year":"1998"},{"key":"R13","series-title":"AJR","first-page":"1471","article-title":"Unique linear and nodular MR enhancement pattern in schistosomiasis of the central nervous system","volume":"177","author":"Sanelli","year":"2001"},{"key":"R14","series-title":"Mem Inst Oswaldo Cruz","first-page":"707","article-title":"Factors involved in Schistosoma mansoni infection, in rural area of northeast Brazil","volume":"92","author":"Coutinho","year":"1997"},{"key":"R15","series-title":"Rev Inst Med Trop","first-page":"179","article-title":"Neuroschistosomiasis due to Schistosoma mansoni: a review of pathogenesis, clinical syndromes and diagnostic approaches","volume":"47","author":"Carvalho","year":"2005"},{"key":"R16","series-title":"J Korean Med Sci","first-page":"57","article-title":"Imported CNS schistosomiasis: a case report","volume":"10","author":"Lee","year":"1995"},{"key":"R17","series-title":"J Trop Med Hyg","first-page":"15","article-title":"The relation between involvement of the central nervous system in schistosomiasis mansoni and the clinical forms of the parasitosis. 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