{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:06:43Z","timestamp":1756462003231},"reference-count":21,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,2,1]]},"abstract":"<jats:p>African histoplasmosis, caused by <jats:italic>Histoplasma capsulatum<\/jats:italic> var. <jats:italic>duboisii<\/jats:italic>, is endemic in Africa. The disease usually involves the skin, subcutaneous tissue, and bones. A case of African histoplasmosis presenting as a cutaneous tumor and non-healing wound in a 66-year-old immunocompetent male residing in Africa, the first ever reported following mudbaths and acupuncture, is hereby reported. Diagnosis was confirmed by means of polymerase chain reaction performed on tissue material. The patient was started on long-term itraconazole therapy and he responded well. African histoplasmosis should be included in the differential diagnosis of non-healing wounds or tumor-like lesions, especially in the context of mudbaths in an endemic area.<\/jats:p>","DOI":"10.4269\/ajtmh.2012.11-0557","type":"journal-article","created":{"date-parts":[[2012,2,6]],"date-time":"2012-02-06T21:50:37Z","timestamp":1328565037000},"page":"261-263","source":"Crossref","is-referenced-by-count":18,"title":["An Unusual Cutaneous Tumor: African Histoplasmosis following Mudbaths: Case Report and Review"],"prefix":"10.4269","volume":"86","author":[{"given":"Sotirios","family":"Tsiodras","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miranda","family":"Drogari-Apiranthitou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Pilichos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Leventakos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodoros","family":"Kelesidis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Jose","family":"Buitrago","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios","family":"Petrikkos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis","family":"Panayiotides","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Indian J Chest Dis Allied Sci","first-page":"271","article-title":"Histoplasmosis in Africa: a review","volume":"42","author":"Gugnani","year":"2000"},{"key":"R2","series-title":"Arch Dermatol","first-page":"595","article-title":"Histoplasmosis due to Histoplasma capsulatum var. duboisii in a Canadian immigrant","volume":"114","author":"Nethercott","year":"1978"},{"key":"R3","series-title":"Emerg Infect Dis","first-page":"1647","article-title":"Literature review and case histories of Histoplasma capsulatum var. duboisii infections in HIV-infected patients","volume":"13","author":"Loulergue","year":"2007"},{"key":"R4","series-title":"Eur J Clin Microbiol Infect Dis","first-page":"665","article-title":"Detection of imported histoplasmosis in serum of HIV-infected patients using a real-time PCR-based assay","volume":"10","author":"Buitrago","year":"2006"},{"key":"R5","series-title":"Ann Soc Belge Med Trop","first-page":"569","article-title":"A case of African histoplasmosis; with a mycological note on Histoplasma duboisii n. sp. 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