{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T14:09:18Z","timestamp":1791209358259,"version":"4.1.0"},"reference-count":20,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,4,1]]},"abstract":"<jats:p>Chikungunya virus (CHIKV) and dengue virus (DENV) are circulating individually in the state of West Bengal, India. However, after 1965 the dual-infection caused by both viruses had not been recorded until 2010. In 2010, an investigation of the febrile cases was carried out to confirm the involvement of both viruses simultaneously. A total of 550 blood samples were tested for the detection of immunoglobulin M (IgM) antibody against both CHIKV and DENV. Serology by the enzyme-linked immunosorbent assay method confirmed that 131 (23.8%) and 104 (18.9%) patients had IgM antibody against CHIKV and DENV, respectively, whereas 68 (12.4%) had IgM antibodies against both CHIKV and DENV. Fever, joint pain, rashes, headache, myalgia, and nausea\/vomiting are the common features in the case of both monotypic and dual-infection. Severe arthralgia and swelling of joints were common only in CHIKV-positive cases and abdominal pain was mainly associated with DENV infection. Diarrhea was reported only by the dual-infected patients (16.2%).<\/jats:p>","DOI":"10.4269\/ajtmh.2012.11-0704","type":"journal-article","created":{"date-parts":[[2012,4,4]],"date-time":"2012-04-04T22:40:09Z","timestamp":1333579209000},"page":"720-723","source":"Crossref","is-referenced-by-count":66,"title":["A Comparative Study of Clinical Features between Monotypic and Dual Infection Cases with Chikungunya Virus and Dengue Virus in West Bengal, India"],"prefix":"10.4269","volume":"86","author":[{"given":"Debjani","family":"Taraphdar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arindam","family":"Sarkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bansi B.","family":"Mukhopadhyay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyamalendu","family":"Chatterjee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Med J Malaysia","first-page":"335","article-title":"Coinfection of dengue virus and chikungunya virus in two patients with acute febrile illness","volume":"62","author":"Nayar","year":"2007"},{"key":"R2","series-title":"Emerg Infect Dis","first-page":"1077","article-title":"Co-infections with chikungunya virus and dengue virus in Delhi, India","volume":"5","author":"Chahar","year":"2009"},{"key":"R3","series-title":"Indian J Med Res","first-page":"676","article-title":"Virological investigation of the epidemic of hemorrhagic fever in Calcutta: isolation of three strains of chikungunya virus","volume":"52","author":"Shah","year":"1964"},{"key":"R4","series-title":"J Hyg Epidemiol Microbiol Immunol","first-page":"445","article-title":"Epidemiological investigations of chikungunya epidemic at Barsi, Maharashtra","volume":"23","author":"Padbidri","year":"1979"},{"key":"R5","series-title":"Trans R Soc Trop Med Hyg","first-page":"491","article-title":"Disappearance of chikungunya virus from India and South East Asia","volume":"80","author":"Pavri","year":"1986"},{"key":"R6","series-title":"Indian J Med Microbiol","first-page":"83","article-title":"Re-emergence of chikungunya virus in India","volume":"24","author":"Ravi","year":"2006"},{"key":"R7","series-title":"Dengue and dengue hemorrhagic fever","author":"World Health Organization","year":"2009"},{"key":"R8","series-title":"J Vector Borne Dis","first-page":"197","article-title":"Dengue serosurveillance in Kolkata, facing an epidemic in West Bengal, India","volume":"46","author":"Hati","year":"2009"},{"key":"R9","series-title":"Science","first-page":"1307","article-title":"Concurrent isolation from patient of two arboviruses, chikungunya and dengue type 2","volume":"157","author":"Myers","year":"1967"},{"key":"R10","series-title":"Am J Trop Med Hyg","first-page":"972","article-title":"Dengue and chikungunya virus infections in man in Thailand, 1962\u20131964","volume":"18","author":"Halstead","year":"1967"},{"key":"R11","series-title":"Emerg Infect Dis","first-page":"591","article-title":"Concurrent chikungunya and dengue virus infections during simultaneous outbreaks, Gabon, 2007","volume":"15","author":"Leroy","year":"2009"},{"key":"R12","series-title":"Trans R Soc Trop Med Hyg","first-page":"355","article-title":"First evidence of chikungunya virus infection in Assam, northeast India","volume":"105","author":"Dutta","year":"2011"},{"key":"R13","series-title":"Asian Pac J Trop Biomed","first-page":"97","article-title":"Mass scale screening of common arboviral infections by an affordable, cost effective RT-PCR method","volume":"2","author":"Taraphdar","year":"2012"},{"key":"R14","series-title":"J Clin Microbiol","first-page":"545","article-title":"Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction","volume":"30","author":"Lanciotti","year":"1992"},{"key":"R15","series-title":"Trans R Soc Trop Med Hyg 106:","article-title":"2012. Rapid spread of chikungunya virus following its resurgence during 2006 in West Bengal, India","author":"Taraphdar"},{"key":"R16","series-title":"Euro Surveill","first-page":"3019","article-title":"Resurgence of chikungunya virus in India: an emerging threat","volume":"11","author":"Saxena","year":"2006"},{"key":"R17","series-title":"Indian J Med Res","first-page":"311","article-title":"A study on chikungunya outbreak during 2007 in Kerala, south India","volume":"129","author":"Kannan","year":"2009"},{"key":"R18","series-title":"Asian Pac J Trop Med","first-page":"364","article-title":"Sero diagnosis of dengue activity in an unknown febrile outbreak at the Siliguri Town, District Darjeeling, West Bengal","volume":"5","author":"Taraphdar","year":"2010"},{"key":"R19","series-title":"J Gen Virol","first-page":"1945","article-title":"A226V mutation in virus during the 2007chikungunya outbreak in Kerala, India","volume":"89","author":"Kumar","year":"2008"},{"key":"R20","series-title":"Lancet Infect Dis","first-page":"319","article-title":"Chikungunya, an epidemic arbovirosis","volume":"7","author":"Pialoux","year":"2007"}],"container-title":["The American Society of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/86\/4\/article-p720.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/86\/4\/article-p720.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/86\/4\/article-p720.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T17:56:29Z","timestamp":1723053389000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/86\/4\/article-p720.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,1]]},"references-count":20,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.2012.11-0704","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,1]]}}}