{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:09:48Z","timestamp":1792638588076,"version":"4.5.0"},"reference-count":40,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,9,5]]},"abstract":"<jats:p>The risk factors for maternal anemia (hemoglobin level less than 110 g\/L) were studied in human immunodeficiency virus\u2013negative pregnant women in Benin at the time of first antenatal visit and prior to any prevention. Data for the first 1,005 pregnant women included in a multicentre randomized controlled trial were analyzed. Anemia was common (68.3%), and malaria and helminth infestations were prevalent in 15.2% and 11.1% of the women. A total of 33.3%, 31.3% and 3.6% of the women were iron, folic acid and vitamin B12 deficient, respectively. These parasitic infections and nutrient deficiencies were associated with a high risk of anemia. Twenty-one percent, 15%, 12%, 11% and 7% of anemia were attributable to malnutrition, malaria, iron, folic acid deficiencies, and helminth infestations, respectively. Most anemia was caused by factors that could be prevented by available tools, stressing the need to reinforce their implementation and to evaluate their effectiveness throughout the course of the pregnancy.<\/jats:p>","DOI":"10.4269\/ajtmh.2012.11-0706","type":"journal-article","created":{"date-parts":[[2012,9,5]],"date-time":"2012-09-05T18:18:59Z","timestamp":1346869139000},"page":"418-424","source":"Crossref","is-referenced-by-count":63,"title":["Maternal Anemia at First Antenatal Visit: Prevalence and Risk Factors in a Malaria-Endemic Area in Benin"],"prefix":"10.4269","volume":"87","author":[{"given":"Sma\u00efla","family":"Ou\u00e9draogo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghislain K.","family":"Koura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manfred M. 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A Tabulation of Available Information","author":"World Health Organization","year":"1992"},{"key":"R2","series-title":"Worldwide Prevalence of Anaemia 1993\u20132005","author":"World Health Organization","year":"2008"},{"key":"R3","series-title":"Food Nutr Bull","first-page":"S99","article-title":"Iron deficiency: global prevalence and consequences","volume":"24","author":"Stoltzfus","year":"2003"},{"key":"R4","series-title":"Am J Trop Med Hyg","first-page":"414","article-title":"Maternal anemia in Benin: prevalence, risk factors, and association with low birth weight","volume":"85","author":"Bodeau-Livinec","year":"2011"},{"key":"R5","series-title":"J Nutr","first-page":"636S","article-title":"An analysis of anemia and child mortality","volume":"131","author":"Brabin","year":"2001"},{"key":"R6","series-title":"Am J Trop Med Hyg","first-page":"44","article-title":"An update on anemia in less developed countries","volume":"77","author":"Tolentino","year":"2007"},{"key":"R7","series-title":"Br J Obstet Gynaecol","first-page":"385","article-title":"Anaemia in pregnancy in developing countries","volume":"105","author":"van den Broek","year":"1998"},{"key":"R8","series-title":"Preventing and Controlling Iron Deficiency through Primary Care","author":"De Maeyer","year":"1989"},{"key":"R9","series-title":"Towards an Integrated Approach for Effective Anaemia Control","author":"World Health Organization\/United Nations Children's Fund","year":"2004"},{"key":"R10","series-title":"Food Nutr Bull","first-page":"3","article-title":"Determinants of anemia among pregnant women in Mali","volume":"27","author":"Ayoya","year":"2006"},{"key":"R11","series-title":"Am J Clin Nutr","first-page":"247S","article-title":"Etiology of anemia in pregnancy in south Malawi","volume":"72","author":"van den Broek","year":"2000"},{"key":"R12","series-title":"Am J Clin Nutr","first-page":"776","article-title":"Prevalence of iron deficiency with and without concurrent anemia in population groups with high prevalences of malaria and other infections: a study in C\u00f4te d'Ivoire","volume":"74","author":"Asobayire","year":"2001"},{"key":"R13","series-title":"Am J Clin Nutr","first-page":"546","article-title":"Adjusting plasma ferritin concentrations to remove the effects of subclinical inflammation in the assessment of iron deficiency: a meta-analysis","volume":"92","author":"Thurnham","year":"2010"},{"key":"R14","series-title":"Am J Trop Med Hyg","first-page":"599","article-title":"Comparison of methods for the rapid laboratory assessment of children with malaria","volume":"65","author":"Planche","year":"2001"},{"key":"R15","series-title":"Bench Aids in the Diagnosis of Intestinal Parasites","author":"World Health Organization","year":"1994"},{"key":"R16","series-title":"J Infect Dis","first-page":"163","article-title":"Decreased susceptibility to Plasmodium falciparum infection in pregnant women with iron deficiency","volume":"198","author":"Kabyemela","year":"2008"},{"key":"R17","series-title":"Lancet","first-page":"2052","article-title":"Effects of subclinical infection on plasma retinol concentrations and assessment of prevalence of vitamin A deficiency: meta-analysis","volume":"362","author":"Thurnham","year":"2003"},{"key":"R18","series-title":"Low Birth Weight, Report of Meeting","author":"United nations Administrative Committee on Coordination","year":"2000"},{"key":"R19","series-title":"JAMA","first-page":"511","article-title":"Facts and artifacts about anemia and preterm delivery","volume":"262","author":"Klebanoff","year":"1989"},{"key":"R20","series-title":"Trans R Soc Trop Med Hyg","first-page":"72","article-title":"Anaemia and Schistosoma haematobium infection in the north-eastern province of Kenya","volume":"72","author":"Greenham","year":"1978"},{"key":"R21","series-title":"Am J Clin Nutr","article-title":"Anemia vs. iron deficiency: increased risk of preterm delivery in a prospective study","volume":"55","author":"Scholl","year":"1992"},{"key":"R22","series-title":"J Nutr","first-page":"590S","article-title":"Is there a causal relationship between iron deficiency or iron-deficiency anemia and weight at birth, length of gestation and perinatal mortality?","volume":"131","author":"Rasmussen","year":"2001"},{"key":"R23","series-title":"Bull World Health Organ","first-page":"916","article-title":"Anaemia during pregnancy in Burkina Faso, west Africa, 1995\u201396: prevalence and associated factors","volume":"77","author":"Meda","year":"1999"},{"key":"R24","series-title":"Clin Haematol","first-page":"365","article-title":"Iron deficiency in the tropics","volume":"11","author":"Fleming","year":"1982"},{"key":"R25","series-title":"Blood Cells","first-page":"401","article-title":"Hematopoiesis in human malaria","volume":"16","author":"Abdalla","year":"1990"},{"key":"R26","series-title":"Am J Hematol","first-page":"155","article-title":"Mechanisms of erythropoiesis inhibition by malarial pigment and malaria-induced proinflammatory mediators in an in vitro model","volume":"86","author":"Awandare","year":"2011"},{"key":"R27","series-title":"J Nutr","first-page":"2527","article-title":"Hookworms, malaria and vitamin A deficiency contribute to anemia and iron deficiency among pregnant women in the plains of Nepal","volume":"130","author":"Dreyfuss","year":"2000"},{"key":"R28","series-title":"PLoS Negl Trop Dis","first-page":"e291","article-title":"Hookworm-related anaemia among pregnant women: a systematic review","volume":"2","author":"Brooker","year":"2008"},{"key":"R29","series-title":"Weekly Iron-Folic Acid Supplementations (WIFS) in Women of Reproductive Age: Its Role in Promoting Optimal Maternal and Child Health Position Statement","author":"World Health Organization","year":"2009"},{"key":"R30","series-title":"Am J Clin Nutr","first-page":"257S","article-title":"Iron 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