{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T16:53:49Z","timestamp":1761929629874},"reference-count":24,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,10,3]]},"abstract":"<jats:p>Little data are available regarding the association of ancylostomiasis with overt gastrointestinal bleeding. This 6-year retrospective study describes the clinical and biological profiles of unexpectedly identified ancylostomiasis in a 4-month-old baby and four adults; they presented with melena and were referred for urgent diagnostic gastrointestinal endoscopy, which confirmed numerous small intestine injuries with surrounding blood pools caused by <jats:italic>Ancylostoma duodenale<\/jats:italic> worms. Gastric erosions were also encountered in one patient. Uniquely, worm biological activities were recorded live <jats:italic>in vivo<\/jats:italic>, including mucosal invasion through a vigorous, rapid piercing process, repeated bloodsucking habits, and gut appearance during the stages of feeding, digestion, and excretion in male and female worms. In conclusion, ancylostomiasis-induced melena may occur in all ages from infants to the elderly. Worm bloodfeeding occurs after quick mucosal piercing, with blood loss being aggravated by a repeated feeding behavior. After treatment is started, bleeding stops rapidly in response to anthelmintic therapy.<\/jats:p>","DOI":"10.4269\/ajtmh.2012.12-0018","type":"journal-article","created":{"date-parts":[[2012,9,21]],"date-time":"2012-09-21T15:15:22Z","timestamp":1348240522000},"page":"701-705","source":"Crossref","is-referenced-by-count":11,"title":["In Vivo Endoscopic Imaging of Ancylostomiasis-Induced Gastrointestinal Bleeding: Clinical and Biological Profiles"],"prefix":"10.4269","volume":"87","author":[{"given":"Maha","family":"Barakat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naglaa","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Nasr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Lancet","first-page":"1521","article-title":"Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm","volume":"367","author":"Bethony","year":"2006"},{"key":"R2","series-title":"Trends Parasitol","first-page":"327","article-title":"New technologies for control of hookworm infections","volume":"22","author":"Hotez","year":"2006"},{"key":"R3","series-title":"N Engl J Med","first-page":"799","article-title":"Hookworm infection","volume":"351","author":"Hotez","year":"2004"},{"key":"R4","series-title":"J Egypt Soc Parasitol","first-page":"447","article-title":"Some epidemiological studies on Ancylostoma duodenale infection","volume":"13","author":"El-Kholy","year":"1983"},{"issue":"(Suppl)","key":"R5","series-title":"J Egypt Soc Parasitol","first-page":"371","article-title":"Prevalence of intestinal parasitosis in a rural population in Egypt, and its relation to socio-demographic characteristics","volume":"39","author":"Bakr","year":"2009"},{"key":"R6","series-title":"Markell and Voge's Medical Parasitology","first-page":"239","article-title":"The intestinal nematodes","author":"John","year":"2006"},{"key":"R7","series-title":"Foundations of Parasitology","first-page":"419","article-title":"Nematodes: strongyloidea, bursate rhabditidans","author":"Roberts","year":"2010"},{"key":"R8","series-title":"Acta Trop","first-page":"265","article-title":"Infantile hookworm disease in China. 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