{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:33:41Z","timestamp":1791304421717,"version":"4.3.1"},"reference-count":40,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,7,2]]},"abstract":"<jats:p>Our objective was to identify local animal reservoirs of leptospirosis to explain the unusual features of <jats:italic>Leptospira<\/jats:italic> strains recently described among patients on the island of Mayotte. By means of a microscopic agglutination test using local clinical isolates, we found that 11.2% of black rats were seropositive to <jats:italic>Leptospira<\/jats:italic>, whereas 10.2% of flying foxes, 2% of lemurs, 93.1% of domestic dogs, and 87.5% of stray dogs were seropositive. As observed in humans, Mini was the main serogroup circulating in animals, whereas serogroup Icterohaemorrhagiae was absent. Using quantitative polymerase chain reaction, we also showed that 29.8% of rats carried leptospires in their kidneys. The sequencing of 16S rRNA gene sequences of <jats:italic>Leptospira<\/jats:italic> found in black rat kidneys identified four genomospecies (<jats:italic>Leptospira borgpetersenii<\/jats:italic>, <jats:italic>Leptospira interrogans<\/jats:italic>, <jats:italic>Leptospira kirschneri,<\/jats:italic> and <jats:italic>L. borgpetersenii<\/jats:italic> group B), which established black rats as the major source of leptospirosis transmission to humans. The origins of such a genetic diversity in <jats:italic>Leptospira<\/jats:italic> strains are discussed.<\/jats:p>","DOI":"10.4269\/ajtmh.2012.12-0102","type":"journal-article","created":{"date-parts":[[2012,7,4]],"date-time":"2012-07-04T20:56:49Z","timestamp":1341435409000},"page":"134-140","source":"Crossref","is-referenced-by-count":46,"title":["Similarities in Leptospira Serogroup and Species Distribution in Animals and Humans in the Indian Ocean Island of Mayotte"],"prefix":"10.4269","volume":"87","author":[{"given":"Am\u00e9lie","family":"Desvars","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Naze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwena\u00ebl","family":"Vourc'h","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Cardinale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Picardeau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Michault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascale","family":"Bourhy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"R1","series-title":"Curr Opin Infect Dis","first-page":"376","article-title":"Leptospirosis","volume":"18","author":"McBride","year":"2005"},{"key":"R2","series-title":"Clin Microbiol Rev","first-page":"296","article-title":"Leptospirosis","volume":"14","author":"Levett","year":"2001"},{"key":"R3","series-title":"J Clin Microbiol","first-page":"307","article-title":"Human Leptospira isolates circulating in Mayotte (Indian Ocean) have unique serological and molecular features","volume":"50","author":"Bourhy","year":"2012"},{"key":"R4","series-title":"PLoS Negl Trop Dis","first-page":"e724","article-title":"Isolation and characterization of new Leptospira genotypes from patients in Mayotte (Indian Ocean)","volume":"4","author":"Bourhy","year":"2010"},{"key":"R5","series-title":"J Wildl Dis","first-page":"870","article-title":"The flying-fox Pteropus seychellensis in Mayotte (Comoros): capture and blood sample methods","volume":"45","author":"Desvars","year":"2009"},{"key":"R6","series-title":"Zoo Animal and Wildlife Immobilization and Anesthesia","author":"West","year":"2007"},{"key":"R7","author":"Parliament and the Council of the European Union","year":"2010"},{"key":"R8","series-title":"Leptospira and Leptospirosis","author":"Faine","year":"1999"},{"key":"R9","series-title":"Stem Cells Dev","first-page":"825","article-title":"Generation of high-level stable transgene expressing human embryonic stem cell lines using Chinese hamster elongation factor-1alpha promoter system","volume":"17","author":"Kwok-Keung","year":"2008"},{"key":"R10","series-title":"Diagn Microbiol Infect Dis","first-page":"247","article-title":"Detection of pathogenic Leptospira spp. through TaqMan polymerase chain reaction targeting the LipL32 gene","volume":"64","author":"Stoddard","year":"2009"},{"key":"R11","series-title":"J Clin Microbiol","first-page":"2219","article-title":"Polymerase chain reaction for detection of Leptospira spp. in clinical sample","volume":"30","author":"M\u00e9rien","year":"1992"},{"key":"R12","series-title":"Res Microbiol","first-page":"333","article-title":"Interest of partial 16S rDNA gene sequences to resolve heterogeneities between Leptospira collections: application to L. meyeri","volume":"151","author":"Postic","year":"2000"},{"key":"R13","series-title":"Esp\u00e8ces Exotiques Envahissantes dans les Collectivit\u00e9s Fran\u00e7aises d\u2019Outre-Mer. 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