{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T16:48:00Z","timestamp":1780764480783,"version":"3.54.1"},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,9,15]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p><jats:italic>Strongyloides stercoralis<\/jats:italic> affects more than half a billion people worldwide, and hyperinfection in immunocompromised patients can be fatal. Elimination of this neglected tropical disease requires field-applicable diagnostic tools. We conducted a laboratory evaluation of a lateral flow rapid dipstick test (SsRapid\u2122) using sera samples from a <jats:italic>Strongyloides<\/jats:italic>-endemic area in northeast Thailand. Group 1 was <jats:italic>S. stercoralis<\/jats:italic>-positive and larvae- and\/or antibody-positive (according to the IgG ELISA) (<jats:italic>N<\/jats:italic> = 100). Group 2 had negative fecal examination and IgG ELISA results (<jats:italic>N<\/jats:italic> = 25). Group 3 had other parasitic infections and negative IgG ELISA results (<jats:italic>N<\/jats:italic> = 25). The results showed good diagnostic sensitivity (82%) and excellent specificity (96%). Suggested improvements in the SsRapid\u2122 test include increased diagnostic sensitivity and conversion to the more robust cassette format. Field studies should be performed as well.<\/jats:p>","DOI":"10.4269\/ajtmh.21-0317","type":"journal-article","created":{"date-parts":[[2021,7,8]],"date-time":"2021-07-08T19:44:21Z","timestamp":1625773461000},"page":"688-691","source":"Crossref","is-referenced-by-count":16,"title":["Evaluation of a Rapid IgG4 Lateral Flow Dipstick Test to Detect Strongyloides stercoralis Infection in Northeast Thailand"],"prefix":"10.4269","volume":"105","author":[{"given":"Rahmah","family":"Noordin","sequence":"first","affiliation":[{"name":"1Institute for Research in Molecular Medicine, Universiti Sains Malaysia, 11800 Penang, Malaysia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nor Suhada","family":"Anuar","sequence":"additional","affiliation":[{"name":"1Institute for Research in Molecular Medicine, Universiti Sains Malaysia, 11800 Penang, Malaysia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nor Mustaiqazah","family":"Juri","sequence":"additional","affiliation":[{"name":"1Institute for Research in Molecular Medicine, Universiti Sains Malaysia, 11800 Penang, Malaysia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phattharaphon","family":"Wongphutorn","sequence":"additional","affiliation":[{"name":"2Biomedical Science Program, Graduate School, Khon Kaen University, Khon Kaen, Thailand;"},{"name":"5Cholangiocarcinoma Research Institute (CARI), Khon Kaen University, Khon Kaen, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sirowan","family":"Ruantip","sequence":"additional","affiliation":[{"name":"2Biomedical Science Program, Graduate School, Khon Kaen University, Khon Kaen, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kulthida Y.","family":"Kopolrat","sequence":"additional","affiliation":[{"name":"3Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;"},{"name":"5Cholangiocarcinoma Research Institute (CARI), Khon Kaen University, Khon Kaen, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanika","family":"Worasith","sequence":"additional","affiliation":[{"name":"3Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;"},{"name":"5Cholangiocarcinoma Research Institute (CARI), Khon Kaen University, Khon Kaen, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiraporn","family":"Sithithaworn","sequence":"additional","affiliation":[{"name":"4Faculty of Medicine, Mahasarakham University, Mahasarakham, Thailand;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paiboon","family":"Sithithaworn","sequence":"additional","affiliation":[{"name":"3Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;"},{"name":"5Cholangiocarcinoma Research Institute (CARI), Khon Kaen University, Khon Kaen, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/105\/3\/article-p688.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/105\/3\/article-p688.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,23]],"date-time":"2021-09-23T13:03:35Z","timestamp":1632402215000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/105\/3\/article-p688.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,15]]},"references-count":0,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.21-0317","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,15]]}}}