{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T05:41:43Z","timestamp":1772775703397,"version":"3.50.1"},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,11,3]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>We conducted a nationally representative population-based survey in 60 districts from 15 Indian states covering all five geographic regions during 2017\u20132018 to estimate the age specific seroprevalence of dengue. Of the 12,300 sera collected, 4,955 were positive for IgG antibodies against dengue virus using IgG Indirect ELISA indicating past dengue infection. We tested 4,948 sera (seven had inadequate volume) positive for IgG antibodies on indirect ELISA using anti-dengue IgG capture ELISA to estimate the proportion of dengue infections with high antibody titers, suggestive of acute or recent secondary infection. Of the 4,948 sera tested, 529 (10.7%; 95% CI: 9.4\u201312.1) were seropositive on IgG capture ELISA. The proportions of dengue infections with high titers were 1.1% in the northeastern, 1.5% in the eastern, 6.2% in the western, 12.2% in the southern, and 16.7% in the northern region. The distribution of dengue infections varied across geographic regions, with a higher proportion of infections with high antibody titer in the northern and southern regions of India. The study findings could be useful for planning facilities for clinical management of dengue infections.<\/jats:p>","DOI":"10.4269\/ajtmh.21-0386","type":"journal-article","created":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T12:04:27Z","timestamp":1628510667000},"page":"1277-1280","source":"Crossref","is-referenced-by-count":4,"title":["Seroprevalence of Dengue Infection Using IgG Capture ELISA in India, 2017\u20132018"],"prefix":"10.4269","volume":"105","author":[{"given":"Muthusamy","family":"Santhosh Kumar","sequence":"first","affiliation":[{"name":"1Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Kamaraj","sequence":"additional","affiliation":[{"name":"1Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siraj Ahmed","family":"Khan","sequence":"additional","affiliation":[{"name":"2ICMR-Regional Medical Research Centre, Northeast Region, Dibrugarh, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramesh Reddy","family":"Allam","sequence":"additional","affiliation":[{"name":"3Science Health Allied Research Education India, Hyderabad, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pradip V.","family":"Barde","sequence":"additional","affiliation":[{"name":"4ICMR-National Institute of Research in Tribal Health, Jabalpur, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhagirathi","family":"Dwibedi","sequence":"additional","affiliation":[{"name":"5ICMR-Regional Medical Research Centre, Bhubaneswar, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suman","family":"Kanungo","sequence":"additional","affiliation":[{"name":"6ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uday","family":"Mohan","sequence":"additional","affiliation":[{"name":"7King George\u2019s Medical University, Lucknow, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suman","family":"Sundar Mohanty","sequence":"additional","affiliation":[{"name":"8ICMR, National Institute for Implementation Research on Non-Communicable Diseases, Jodhpur, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subarna","family":"Roy","sequence":"additional","affiliation":[{"name":"9ICMR-National Institute of Traditional Medicine, Belagavi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivek","family":"Sagar","sequence":"additional","affiliation":[{"name":"10Postgraduate Institute of Medical Education and Research, Chandigarh, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepali","family":"Savargaonkar","sequence":"additional","affiliation":[{"name":"11ICMR-National Institute of Malaria Research, New Delhi, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Babasaheb V.","family":"Tandale","sequence":"additional","affiliation":[{"name":"12ICMR-National Institute of Virology, Pune, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roshan Kamal","family":"Topno","sequence":"additional","affiliation":[{"name":"13ICMR-Rajendra Memorial Research Institute of Medical Sciences, Patna, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. P. Girish","family":"Kumar","sequence":"additional","affiliation":[{"name":"1Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Sabarinathan","sequence":"additional","affiliation":[{"name":"1Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. Saravana","family":"Kumar","sequence":"additional","affiliation":[{"name":"1Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Karunakaran","sequence":"additional","affiliation":[{"name":"1Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annamma","family":"Jose","sequence":"additional","affiliation":[{"name":"1Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Provash","family":"Sadhukhan","sequence":"additional","affiliation":[{"name":"6ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. S.","family":"Toteja","sequence":"additional","affiliation":[{"name":"8ICMR, National Institute for Implementation Research on Non-Communicable Diseases, Jodhpur, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shanta","family":"Dutta","sequence":"additional","affiliation":[{"name":"6ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manoj","family":"Murhekar","sequence":"additional","affiliation":[{"name":"1Indian Council of Medical Research (ICMR)-National Institute of Epidemiology, Chennai, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/105\/5\/article-p1277.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/105\/5\/article-p1277.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T14:33:05Z","timestamp":1635949985000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/105\/5\/article-p1277.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,3]]},"references-count":0,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.21-0386","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,3]]}}}