{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T18:34:33Z","timestamp":1793644473659,"version":"4.5.1"},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","license":[{"start":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T00:00:00Z","timestamp":1643760000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,2]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Echinococcosis is a zoonotic parasitic disease that is highly endemic to the Qinghai province of China. Limited data are available on the prevalence of the causal pathogen, <jats:italic>Echinococcus<\/jats:italic> spp., in definitive hosts in this region. Thus, the aim of this study was to evaluate the prevalence of <jats:italic>Echinococcus<\/jats:italic> spp. in wild foxes and stray dogs in Qinghai province. Five hundred and twenty-eight feces from wild foxes and 277 from stray dogs were collected from 11 counties in the Golog, Yushu, and Haixi prefectures and screened for <jats:italic>Echinococcus<\/jats:italic> spp. using copro-DNA polymerase chain reaction (PCR). In total, 5.5% of wild foxes and 15.2% of stray dogs tested positive for <jats:italic>Echinococcus<\/jats:italic> spp. The prevalence rates of <jats:italic>Echinococcus<\/jats:italic> spp. in wild foxes in Golog, Yushu, and Haixi were 7.3%, 5.2%, and 1.9%, respectively. In stray dogs, these rates were 13.3%, 17.3%, and 0%, respectively. Sequencing analysis determined that <jats:italic>Echinococcus multilocularis<\/jats:italic> was the most prevalent species, occurring in 4.0% and 12.6% of wild foxes and stray dogs, respectively. <jats:italic>Echinococcus shiquicus<\/jats:italic> was observed in 1.5% of wild foxes and 0.7% of stray dogs. <jats:italic>Echinococcus granulosus<\/jats:italic> was observed only in wild dogs, with a prevalence rate of 1.8%. To our knowledge, this is the first report on the prevalence of <jats:italic>E. shiquicus<\/jats:italic> in dogs in Qinghai province. The current results improve our understanding of the transmission and dissemination of human echinococcosis and suggest that exposure to the eggs of <jats:italic>E. multilocularis<\/jats:italic> harbored by wild foxes and stray dogs may pose a great risk of alveolar echinococcosis to humans in Qinghai province.<\/jats:p>","DOI":"10.4269\/ajtmh.21-0622","type":"journal-article","created":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T14:50:48Z","timestamp":1636987848000},"page":"718-723","source":"Crossref","is-referenced-by-count":14,"title":["Prevalence of Echinococcus Species in Wild Foxes and Stray Dogs in Qinghai Province, China"],"prefix":"10.4269","volume":"106","author":[{"given":"Huixia","family":"Cai","sequence":"first","affiliation":[{"name":"1Department of Parasite Control, Qinghai Province Institute for Endemic Diseases Prevention and Control, Xining, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[{"name":"2National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuefei","family":"Zhang","sequence":"additional","affiliation":[{"name":"1Department of Parasite Control, Qinghai Province Institute for Endemic Diseases Prevention and Control, Xining, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yayi","family":"Guan","sequence":"additional","affiliation":[{"name":"2National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Ma","sequence":"additional","affiliation":[{"name":"1Department of Parasite Control, Qinghai Province Institute for Endemic Diseases Prevention and Control, Xining, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianping","family":"Cao","sequence":"additional","affiliation":[{"name":"2National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junying","family":"Ma","sequence":"additional","affiliation":[{"name":"1Department of Parasite Control, Qinghai Province Institute for Endemic Diseases Prevention and Control, Xining, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Liu","sequence":"additional","affiliation":[{"name":"1Department of Parasite Control, Qinghai Province Institute for Endemic Diseases Prevention and Control, Xining, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Wu","sequence":"additional","affiliation":[{"name":"3Department of Medical Record Information, Qinghai Provincial Traffic Hospital, Xining, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufang","family":"Liu","sequence":"additional","affiliation":[{"name":"1Department of Parasite Control, Qinghai Province Institute for Endemic Diseases Prevention and Control, Xining, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Liu","sequence":"additional","affiliation":[{"name":"1Department of Parasite Control, Qinghai Province Institute for Endemic Diseases Prevention and Control, Xining, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"1Department of Parasite Control, Qinghai Province Institute for Endemic Diseases Prevention and Control, Xining, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Lei","sequence":"additional","affiliation":[{"name":"1Department of Parasite Control, Qinghai Province Institute for Endemic Diseases Prevention and Control, Xining, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kemei","family":"Shi","sequence":"additional","affiliation":[{"name":"1Department of Parasite Control, Qinghai Province Institute for Endemic Diseases Prevention and Control, Xining, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Zhang","sequence":"additional","affiliation":[{"name":"1Department of Parasite Control, Qinghai Province Institute for Endemic Diseases Prevention and Control, Xining, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiongying","family":"Zhang","sequence":"additional","affiliation":[{"name":"1Department of Parasite Control, Qinghai Province Institute for Endemic Diseases Prevention and Control, Xining, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peizhen","family":"Zhan","sequence":"additional","affiliation":[{"name":"1Department of Parasite Control, Qinghai Province Institute for Endemic Diseases Prevention and Control, Xining, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujuan","family":"Shen","sequence":"additional","affiliation":[{"name":"2National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/106\/2\/article-p718.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/106\/2\/article-p718.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T14:58:57Z","timestamp":1643813937000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/106\/2\/article-p718.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,2]]},"references-count":0,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.21-0622","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,2]]}}}