{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T05:32:52Z","timestamp":1787031172843,"version":"build-2736575974"},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,11,3]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n                  <jats:p>\n                    A lateral flow rapid test for strongyloidiasis will greatly facilitate the control and elimination of the disease. Previously SsRapid prototype rapid test showed high diagnostic specificity to detect\n                    <jats:italic>Strongyloides<\/jats:italic>\n                    infection, determined using non-\n                    <jats:italic>Strongyloides<\/jats:italic>\n                    sera negative by IgG-ELISAs. Since high specificity is crucial before a test is used for public health control activities, further validation of its specificity is needed. Also, it needs to be ascertained whether non-\n                    <jats:italic>Strongyloides<\/jats:italic>\n                    sera positive by IgG-ELISAs and SsRapid are truly positive for\n                    <jats:italic>Strongyloides<\/jats:italic>\n                    or are cases of cross-reactivity. We performed 84 rapid tests (two types of dipsticks and cassettes) using 34 serum samples. They were divided into four groups based on\n                    <jats:italic>Strongyloides<\/jats:italic>\n                    infection and coinfection with other parasites and the availability of recombinant proteins and rapid tests for the latter. Sera was adsorbed using polystyrene microspheres beads separately coated with four recombinant parasite proteins. The small sample size is a limitation of this study; however, the overall results showed that the sera adsorption procedure was successful, and the SsRapid test is specific.\n                  <\/jats:p>","DOI":"10.4269\/ajtmh.21-0674","type":"journal-article","created":{"date-parts":[[2021,8,30]],"date-time":"2021-08-30T09:14:48Z","timestamp":1630314888000},"page":"1214-1217","source":"Crossref","is-referenced-by-count":5,"title":["Serum Adsorption Study to Validate the Specificity of a Rapid Test to Detect Strongyloides stercoralis Infection"],"prefix":"10.4269","volume":"105","author":[{"given":"Rahmah","family":"Noordin","sequence":"first","affiliation":[{"name":"1Institute for Research in Molecular Medicine, Universiti Sains Malaysia, Penang, Malaysia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emelia","family":"Osman","sequence":"additional","affiliation":[{"name":"2Department of Parasitology and Medical Entomology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nor Suhada","family":"Anuar","sequence":"additional","affiliation":[{"name":"1Institute for Research in Molecular Medicine, Universiti Sains Malaysia, Penang, Malaysia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nor Mustaiqazah","family":"Juri","sequence":"additional","affiliation":[{"name":"1Institute for Research in Molecular Medicine, Universiti Sains Malaysia, Penang, Malaysia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anizah","family":"Rahumatullah","sequence":"additional","affiliation":[{"name":"1Institute for Research in Molecular Medicine, Universiti Sains Malaysia, Penang, Malaysia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nur Athirah","family":"Ahmad Hilmi","sequence":"additional","affiliation":[{"name":"1Institute for Research in Molecular Medicine, Universiti Sains Malaysia, Penang, Malaysia;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/105\/5\/article-p1214.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/105\/5\/article-p1214.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T10:32:41Z","timestamp":1635935561000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/105\/5\/article-p1214.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,3]]},"references-count":0,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.21-0674","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,3]]}}}