{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T12:38:23Z","timestamp":1746189503076},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","license":[{"start":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T00:00:00Z","timestamp":1641340800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,5]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Chronic pulmonary aspergillosis can present in four distinct clinical syndromes, one of which is chronic cavitary pulmonary aspergillosis (CCPA). CCPA is generally associated with a mildly immunosuppressed state or, in immunocompetent patients, with structural lung damage. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been associated with reactivation of previous quiescent infections such as tuberculosis and invasive fungal infections, but CCPA in a patient with COVID-19 is rarely reported. Here we present the case of a 57-year-old man with CCPA associated with COVID-19 infection in whom latent aspergilloma was most likely activated after SARS-CoV-2 infection. The patient presented with severe COVID and, after initial response to treatment, started to deteriorate due to reactivation of latent aspergilloma to a more aggressive CCPA form. After confirmation of the diagnosis, the patient was initiated on treatment with voriconazole. He showed a good response to treatment with clinicoradiological response. This case also depicts one of the common causes of clinical deterioration in otherwise recovering COVID-19 patients.<\/jats:p>","DOI":"10.4269\/ajtmh.21-0701","type":"journal-article","created":{"date-parts":[[2021,11,24]],"date-time":"2021-11-24T18:55:04Z","timestamp":1637780104000},"page":"105-107","source":"Crossref","is-referenced-by-count":11,"title":["Case Report: Chronic Cavitatory Pulmonary Aspergillosis after COVID-19"],"prefix":"10.4269","volume":"106","author":[{"given":"Sheetal","family":"Chaurasia","sequence":"first","affiliation":[{"name":"1Department of Pulmonary Medicine, Manipal Hospital Whitefield, Bangalore, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manjunath","family":"Thimmappa","sequence":"additional","affiliation":[{"name":"2Department of Critical Care Medicine, Manipal Hospital Whitefield, Bangalore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saurav","family":"Chowdhury","sequence":"additional","affiliation":[{"name":"1Department of Pulmonary Medicine, Manipal Hospital Whitefield, Bangalore, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/106\/1\/article-p105.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/106\/1\/article-p105.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T12:08:44Z","timestamp":1641384524000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/106\/1\/article-p105.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,5]]},"references-count":0,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.21-0701","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,5]]}}}