{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T13:57:57Z","timestamp":1778853477585,"version":"3.51.4"},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","license":[{"start":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T00:00:00Z","timestamp":1643760000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,2]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Between October 2012 and October 2015, we conducted a community trial to assess the impact of semi-annual (twice yearly) community treatment with albendazole on lymphatic filariasis in Seke Pembe, a village in the Republic of the Congo. Semi-annual community treatment with albendazole has been continued in the community since October 2015. We conducted an additional parasitological assessment survey in October 2019, 6 months after the 14th round of semi-annual treatment. Between October 2012 and October 2015, <jats:italic>Wuchereria bancrofti<\/jats:italic> antigenemia and microfilaremia rates in the community had decreased from 17.3% to 4.7% and from 5.3% to 0.3%, respectively. In October 2019, the antigenemia rate had decreased further to 2.8% (19 of 687). No microfilariae were found in night blood smears from persons with circulating filarial antigenemia (0 of 16), suggesting that <jats:italic>W. bancrofti<\/jats:italic> transmission has been interrupted in Seke Pembe. Semi-annual albendazole treatments also reduced significantly infection rates with soil-transmitted helminths.<\/jats:p>","DOI":"10.4269\/ajtmh.21-0731","type":"journal-article","created":{"date-parts":[[2021,12,20]],"date-time":"2021-12-20T12:52:10Z","timestamp":1640004730000},"page":"729-731","source":"Crossref","is-referenced-by-count":5,"title":["Impact of Semi-Annual Albendazole on Lymphatic Filariasis and Soil-Transmitted Helminth Infection: Parasitological Assessment after 14 Rounds of Community Treatment"],"prefix":"10.4269","volume":"106","author":[{"given":"S\u00e9bastien D. S.","family":"Pion","sequence":"first","affiliation":[{"name":"1Institut de Recherche pour le D\u00e9veloppement, UMI233\/INSERM U1175\/Universit\u00e9 de Montpellier, Montpellier, France;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9dric B.","family":"Chesnais","sequence":"additional","affiliation":[{"name":"1Institut de Recherche pour le D\u00e9veloppement, UMI233\/INSERM U1175\/Universit\u00e9 de Montpellier, Montpellier, France;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary J.","family":"Weil","sequence":"additional","affiliation":[{"name":"2Infectious Diseases Division, Washington University School of Medicine, St. Louis, Missouri;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Louya","sequence":"additional","affiliation":[{"name":"3Programme National de Lutte contre l\u2019Onchocercose, Direction de l\u2019Epid\u00e9miologie et de la Lutte contre la Maladie, Minist\u00e8re de la Sant\u00e9 et de la Population, Brazzaville, Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel","family":"Boussinesq","sequence":"additional","affiliation":[{"name":"1Institut de Recherche pour le D\u00e9veloppement, UMI233\/INSERM U1175\/Universit\u00e9 de Montpellier, Montpellier, France;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fran\u00e7ois","family":"Missamou","sequence":"additional","affiliation":[{"name":"3Programme National de Lutte contre l\u2019Onchocercose, Direction de l\u2019Epid\u00e9miologie et de la Lutte contre la Maladie, Minist\u00e8re de la Sant\u00e9 et de la Population, Brazzaville, Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/106\/2\/article-p729.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/106\/2\/article-p729.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,2]],"date-time":"2022-02-02T14:58:08Z","timestamp":1643813888000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/106\/2\/article-p729.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,2]]},"references-count":0,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.21-0731","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,2]]}}}