{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T14:40:10Z","timestamp":1776436810057,"version":"3.51.2"},"reference-count":15,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,9,14]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Diphtheria is a vaccine-preventable disease and is caused by toxigenic strains of <jats:italic>Corynebacterium diphtheriae<\/jats:italic>. Several case reports have been published in the recent years, and this resurgence of cases has occurred mainly in adolescent and adult populations. Also, several research articles have reported waning immunity against diphtheria in adults who have completed childhood immunization. Thus, it is an important need to conduct larger sero-surveillance studies to understand the cause of rising diphtheria cases. Here, we report a case of a 23-year-old pregnant women of 8 weeks\u2019 gestation who presented to the outpatient department with fever, severe throat pain, odynophagia, dysphagia, neck pain, and neck swelling of 3 days\u2019 duration. On clinical examination, a gray, leathery membrane was noted on the soft palate. An Albert\u2019s stain from the membrane revealed organisms resembling <jats:italic>Corynebacterium diphtheriae<\/jats:italic>. Appropriate treatment was initiated immediately, and follow-up examination at 2 weeks from date of discharge was uneventful. The gray membrane had completely resolved. Contact tracing was done and the appropriate antimicrobial agent was administered. This case study indicates the importance of timely clinical and microbiological diagnosis and reinforces the previously reported resurgence of diphtheria infection.<\/jats:p>","DOI":"10.4269\/ajtmh.21-0746","type":"journal-article","created":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T12:56:32Z","timestamp":1659358592000},"page":"573-575","source":"Crossref","is-referenced-by-count":3,"title":["Case Report: Pharyngeal Diphtheria in a Pregnant Woman from South India"],"prefix":"10.4269","volume":"107","author":[{"given":"Suhas S.","family":"Pattar","sequence":"first","affiliation":[{"name":"Cauvery Multispeciality Hospital, Mysore, India;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Deepashree","sequence":"additional","affiliation":[{"name":"Department of Microbiology, JSS Medical College, Mysore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. N.","family":"Sumana","sequence":"additional","affiliation":[{"name":"Department of Microbiology, JSS Medical College, Mysore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. R.","family":"Sujatha","sequence":"additional","affiliation":[{"name":"Department of Microbiology, JSS Medical College, Mysore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Tejashree","sequence":"additional","affiliation":[{"name":"Department of Microbiology, JSS Medical College, Mysore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raghavendra","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Microbiology, JSS Medical College, Mysore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neetha","family":"Murthy","sequence":"additional","affiliation":[{"name":"Department of Microbiology, JSS Medical College, Mysore, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","year":"2021"},{"key":"b2","year":"2021"},{"key":"b3","series-title":"Indian J Med Microbiol","doi-asserted-by":"publisher","first-page":"247","DOI":"10.4103\/ijmm.IJMM_17_48","article-title":"Resurgence of diphtheria in rural areas of North Karnataka, India","volume":"35","year":"2017"},{"key":"b4","series-title":"J Family Med Prim Care","doi-asserted-by":"publisher","first-page":"5776","DOI":"10.4103\/jfmpc.jfmpc_480_20","article-title":"Diphtheria resurgence in India: a case study from south Karnataka","volume":"9","year":"2020"},{"key":"b5","series-title":"Vaccine","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1016\/j.vaccine.2016.12.024","article-title":"Demand- and supply-side determinants of diphtheria-pertussis-tetanus non-vaccination and dropout in rural India","volume":"35","year":"2017"},{"key":"b6","series-title":"J Pharm Bioallied Sci","doi-asserted-by":"publisher","first-page":"190","DOI":"10.4103\/JPBS.JPBS_245_18","article-title":"Diphtheria: the patch still remains\u2013a case report from the state of Uttarakhand","volume":"11","year":"2019"},{"key":"b7","series-title":"Clin Infect Dis","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1093\/cid\/ciz813","article-title":"Diphtheria in the 21st century: new insights and a wake-up call","volume":"71","year":"2020"},{"key":"b8","year":"201i"},{"key":"b9","series-title":"J Family Med Prim Care","doi-asserted-by":"publisher","first-page":"3253","DOI":"10.4103\/jfmpc.jfmpc_589_19","article-title":"Immune status against diphtheria in healthy adults","volume":"8","year":"2019"},{"key":"b10","series-title":"Am J Trop Med Hyg","doi-asserted-by":"publisher","first-page":"313","DOI":"10.4269\/ajtmh.17-0047","article-title":"Epidemiology of diphtheria in India, 1996\u20132016: implications for prevention and control","volume":"97","year":"2017"},{"key":"b11","series-title":"Indian J Otolaryngol Head Neck Surg","doi-asserted-by":"publisher","first-page":"289","DOI":"10.1007\/s12070-010-0069-6","article-title":"Diphtheria in an adult: How well prepared are we in tackling the disease? A case report","volume":"63","year":"2011"},{"key":"b12","series-title":"Front Public Health","doi-asserted-by":"publisher","first-page":"218","DOI":"10.3389\/fpubh.2017.00218","article-title":"Resurgence of diphtheria in North Kerala, India, 2016: laboratory supported case-based surveillance outcomes","volume":"5","year":"2017"},{"key":"b13","year":"2022"},{"key":"b14","series-title":"Emerg Infect Dis","doi-asserted-by":"publisher","first-page":"953","DOI":"10.3201\/eid2703.203205","article-title":"Addressing reemergence of diphtheria among adolescents through program integration in India","volume":"27","year":"2021"},{"key":"b15","series-title":"BMC Public Health","first-page":"1","article-title":"Preventing the preventable through effective surveillance: The case of diphtheria in a rural district of Maharashtra, India","volume":"13","year":"2013"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/107\/3\/article-p573.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/107\/3\/article-p573.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/107\/3\/article-p573.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T12:33:06Z","timestamp":1663245186000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/107\/3\/article-p573.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,14]]},"references-count":15,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.21-0746","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,14]]}}}