{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,5,19]],"date-time":"2023-05-19T02:28:22Z","timestamp":1684463302177},"reference-count":0,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","license":[{"start":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T00:00:00Z","timestamp":1641340800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,5]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Infants ages &lt; 6 months do not receive azithromycin as part of trachoma control and thus may serve as an infection reservoir in persistently endemic districts. The aim of this study was to determine the population-based <jats:italic>Chlamydia trachomatis<\/jats:italic> infection prevalence and infectious load among infants ages 1\u201312 months in persistently trachoma endemic districts in Amhara, Ethiopia. Across six districts, 475 infants were enumerated, and of these 464 (97.7%) were swabbed for infection testing. The <jats:italic>C. trachomatis<\/jats:italic> infection prevalence in the study area among infants was 0.2% (95% CI: 0.0\u20131.5). Among children ages 0\u20135 years positive for <jats:italic>C. trachomatis<\/jats:italic>, the median load was 31 elementary bodies (EB) (Inter quartile range: 7\u2013244 EB), and the infection-positive infant had a load of 7,755 EB. While it is worth reconsidering azithromycin treatment recommendations for the potential mortality benefits, these results do not support lowering the treatment age for trachoma control.<\/jats:p>","DOI":"10.4269\/ajtmh.21-0873","type":"journal-article","created":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T12:15:46Z","timestamp":1635164146000},"page":"62-65","source":"Crossref","is-referenced-by-count":1,"title":["Population-Based Prevalence of Ocular Chlamydia trachomatis Infection among Infants in the Trachoma Endemic Amhara Region, Ethiopia"],"prefix":"10.4269","volume":"106","author":[{"given":"Scott D.","family":"Nash","sequence":"first","affiliation":[{"name":"1Trachoma Control Program, The Carter Center, Atlanta, Georgia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ambahun","family":"Chernet","sequence":"additional","affiliation":[{"name":"2Trachoma Control Program, The Carter Center, Addis Ababa, Ethiopia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tigist","family":"Astale","sequence":"additional","affiliation":[{"name":"2Trachoma Control Program, The Carter Center, Addis Ababa, Ethiopia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eshetu","family":"Sata","sequence":"additional","affiliation":[{"name":"2Trachoma Control Program, The Carter Center, Addis Ababa, Ethiopia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mulat","family":"Zerihun","sequence":"additional","affiliation":[{"name":"2Trachoma Control Program, The Carter Center, Addis Ababa, Ethiopia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew W.","family":"Nute","sequence":"additional","affiliation":[{"name":"1Trachoma Control Program, The Carter Center, Atlanta, Georgia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberly A.","family":"Jensen","sequence":"additional","affiliation":[{"name":"1Trachoma Control Program, The Carter Center, Atlanta, Georgia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Demelash","family":"Gessese","sequence":"additional","affiliation":[{"name":"2Trachoma Control Program, The Carter Center, Addis Ababa, Ethiopia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zebene","family":"Ayele","sequence":"additional","affiliation":[{"name":"2Trachoma Control Program, The Carter Center, Addis Ababa, Ethiopia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berhanu","family":"Melak","sequence":"additional","affiliation":[{"name":"2Trachoma Control Program, The Carter Center, Addis Ababa, Ethiopia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahteme","family":"Haile","sequence":"additional","affiliation":[{"name":"3Research and Technology Transfer Directorate, Amhara Public Health Institute, Bahir Dar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taye","family":"Zeru","sequence":"additional","affiliation":[{"name":"3Research and Technology Transfer Directorate, Amhara Public Health Institute, Bahir Dar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zerihun","family":"Tadesse","sequence":"additional","affiliation":[{"name":"2Trachoma Control Program, The Carter Center, Addis Ababa, Ethiopia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Kelly Callahan","sequence":"additional","affiliation":[{"name":"1Trachoma Control Program, The Carter Center, Atlanta, Georgia;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/106\/1\/article-p62.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/106\/1\/article-p62.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T12:08:47Z","timestamp":1641384527000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/106\/1\/article-p62.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,5]]},"references-count":0,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.21-0873","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,5]]}}}