{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T09:29:37Z","timestamp":1688117377743},"reference-count":8,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,6,15]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p><jats:italic>Histoplasma capsulatum<\/jats:italic> is the most common endemic mycosis in the United States and can cause disseminated histoplasmosis in immunocompromised patients.1 Although hepatic involvement is common with histoplasmosis, it can be challenging to diagnose. We report a case of a 50-year-old woman receiving adalimumab for rheumatoid arthritis who presented with right upper quadrant pain, fever, jaundice, and dyspnea. The initial working diagnosis was biliary obstruction with potential COVID-19 infection. Endoscopic retrograde cholangiopancreatography suggested Mirizzi syndrome, but successful sphincterotomy failed to improve jaundice over subsequent days. Bronchoscopy and liver biopsy were performed, with the first revealing budding yeast and the later growing <jats:italic>H. capsulatum<\/jats:italic>. The patient improved with the initiation of itraconazole therapy.<\/jats:p>","DOI":"10.4269\/ajtmh.21-1049","type":"journal-article","created":{"date-parts":[[2022,4,11]],"date-time":"2022-04-11T12:56:10Z","timestamp":1649681770000},"page":"1627-1628","source":"Crossref","is-referenced-by-count":1,"title":["Case Report: Histoplasma Hepatitis Presenting as Common Bile Duct Obstruction"],"prefix":"10.4269","volume":"106","author":[{"given":"Brittany","family":"Hjermstad","sequence":"first","affiliation":[{"name":"Department of Medicine, Gastroenterology and Hepatology, Hennepin Healthcare, Minneapolis, Minnesota;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dale","family":"Snover","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Minnesota, Minneapolis, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose D.","family":"Debes","sequence":"additional","affiliation":[{"name":"Department of Medicine, Gastroenterology and Hepatology, Hennepin Healthcare, Minneapolis, Minnesota;"},{"name":"Department of Medicine, University of Minnesota, Minneapolis, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Case Rep Hepatol","first-page":"807537","article-title":"Granulomatous hepatitis secondary to histoplasma infection after treatment with infliximab","volume":"2013","author":"Barrera","year":"2013"},{"key":"b2","doi-asserted-by":"publisher","first-page":"879535","DOI":"10.1086\/521259","volume":"2014","author":"Rihana","year":"2014"},{"key":"b3","series-title":"Clin Infect Dis","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1007\/s11606-018-4383-0","article-title":"Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Disease Society of America","volume":"45","author":"Wheat","year":"2007"},{"key":"b4","series-title":"J Surg Case Rep","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12876-020-01290-3","article-title":"Histoplasmosis hepatitis after orthoptic liver transplantation","volume":"12","author":"Washburn","year":"2017"},{"key":"b5","series-title":"BMC Gastroenterol","doi-asserted-by":"publisher","first-page":"141","DOI":"10.4049\/jimmunol.177.5.3303","article-title":"Cholestasis and disseminated histoplasmosis in a psoriatic patient on infliximab: case report and review of literature","volume":"20","author":"Park","year":"2020"},{"key":"b6","series-title":"J Immunol","doi-asserted-by":"publisher","first-page":"3303","DOI":"10.1016\/j.idc.2010.01.006","article-title":"Characterization of the Histoplasma capsulatum\u2013induced granuloma","volume":"177","year":"2006"},{"key":"b7","series-title":"Infect Dis Clin North Am","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1007\/s11606-018-4383-0","article-title":"Infectious complications associated with immunomodulating biologic agents","volume":"24","author":"Koo","year":"2010"},{"key":"b8","series-title":"J Gen Intern Med","first-page":"769","article-title":"A case of disseminated histoplasmosis in a patient with rheumatoid arthritis on abatacept","volume":"33","author":"Jain","year":"2018"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/106\/6\/article-p1627.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/106\/6\/article-p1627.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/106\/6\/article-p1627.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T20:17:30Z","timestamp":1658261850000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/106\/6\/article-p1627.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,15]]},"references-count":8,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.21-1049","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,15]]}}}