{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T12:56:53Z","timestamp":1781096213414,"version":"3.54.1"},"reference-count":42,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"1","license":[{"start":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T00:00:00Z","timestamp":1657670400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7,13]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Nasarawa and Plateau states of north-central Nigeria have implemented programs to control schistosomiasis (SCH) and soil-transmitted helminths (STH) in children since the 1990s. Statewide mapping surveys were conducted in 2013, when 11,332 school-aged children were sampled from 226 schools. The local government areas (LGAs) then received varying combinations of mass drug administration (MDA) for the next 5 years. We revisited 196 (87%) schools in 2018 plus an additional six (202 schools in total), sampling 9,660 children. We calculated overall prevalence and intensity of infection and evaluated associations with gender; age; behaviors; water, sanitation, and hygiene (WASH); and treatment regimen. Urine heme detection dipsticks were used for <jats:italic>Schistosoma hematobium<\/jats:italic> in both surveys, with egg counts added in 2018. Stool samples were examined by Kato-Katz for <jats:italic>Ascaris lumbricoides<\/jats:italic>, <jats:italic>Trichuris trichiura<\/jats:italic>,<jats:italic> Schistosoma mansoni<\/jats:italic>, and hookworm. Schistosomiasis prevalence among sampled students dropped from 12.9% (95% confidence interval [CI]: 11.1\u201314.9%) to 9.0% (95% CI: 7.5\u201310.9%), a statistically significant change (<jats:italic>P<\/jats:italic> &lt; 0.05). In 2018, eight LGAs still had &gt; 1% of children with heavy-intensity schistosome infections. Prevalence of STH infection did not significantly change, with 10.8% (95% CI: 9.36\u201312.5%) of children positive in 2013 and 9.4% (95% CI: 8.0\u201310.9%) in 2018 (<jats:italic>P<\/jats:italic> = 0.182). Heavy-intensity STH infections were found in &lt; 1% of children with hookworm, and none in children with <jats:italic>A. lumbricoides<\/jats:italic> or <jats:italic>T. trichiura<\/jats:italic> in either study. The WASH data were collected in 2018, indicating 43.6% of schools had a latrine and 14.4% had handwashing facilities. Although progress is evident, SCH remains a public health problem in Nasarawa and Plateau states.<\/jats:p>","DOI":"10.4269\/ajtmh.21-1207","type":"journal-article","created":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T12:12:06Z","timestamp":1652703126000},"page":"132-142","source":"Crossref","is-referenced-by-count":10,"title":["Impact of Three to Five Rounds of Mass Drug Administration on Schistosomiasis and Soil-Transmitted Helminths in School-Aged Children in North-Central Nigeria"],"prefix":"10.4269","volume":"107","author":[{"given":"Emily","family":"Griswold","sequence":"first","affiliation":[{"name":"The Carter Center, Atlanta, Georgia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abel","family":"Eigege","sequence":"additional","affiliation":[{"name":"The Carter Center, Jos, Nigeria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solomon","family":"Adelamo","sequence":"additional","affiliation":[{"name":"The Carter Center, Jos, Nigeria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bulus","family":"Mancha","sequence":"additional","affiliation":[{"name":"The Carter Center, Jos, Nigeria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nwodu","family":"Kenrick","sequence":"additional","affiliation":[{"name":"The Carter Center, Jos, Nigeria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohana","family":"Sambo","sequence":"additional","affiliation":[{"name":"The Carter Center, Jos, Nigeria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Ajiji","sequence":"additional","affiliation":[{"name":"Plateau State Ministry of Health, Jos, Nigeria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gideon","family":"Zam","sequence":"additional","affiliation":[{"name":"Nasarawa State Ministry of Health, Lafia, Nigeria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob","family":"Solomon","sequence":"additional","affiliation":[{"name":"Federal Ministry of Health, Abuja, Nigeria;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"O. 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