{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:42:23Z","timestamp":1761007343551,"version":"build-2065373602"},"reference-count":20,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","license":[{"start":{"date-parts":[[2022,3,9]],"date-time":"2022-03-09T00:00:00Z","timestamp":1646784000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,3,9]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>We provide evidence of concurrent and close sequential infections between SARS-CoV-2 and select arboviruses\u2014namely, chikungunya virus (CHIKV); dengue viruses 1, 2, and 3 (DENV1\u20133), and Zika virus (ZIKV)\u2014in patients in Guerrero, southwest Mexico, in 2020\u20132021. The study population consisted of 176 febrile patients with laboratory evidence of SARS-CoV-2 infection. Sera from all patients were serologically and antigenically tested for seven arboviruses known to occur in Guerrero. Eighteen patients contained CHIKV IgM, six of whom also contained CHIKV RNA. Another 16 patients contained flavivirus antigen. The flaviviruses responsible for the infections were identified by plaque reduction neutralization test as DENV1 (two patients), DENV2 (five patients), DENV3 (three patients), ZIKV (three patients), and an undetermined flavivirus (three patients). In summary, we identified patients in Guerrero, Mexico, with concurrent or recent sequential infections between SARS-CoV-2 and select arboviruses, exemplifying the importance of performing differential diagnosis in regions where these viruses cocirculate.<\/jats:p>","DOI":"10.4269\/ajtmh.21-1216","type":"journal-article","created":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T10:18:57Z","timestamp":1643019537000},"page":"896-899","source":"Crossref","is-referenced-by-count":1,"title":["Evidence of Coinfections between SARS-CoV-2 and Select Arboviruses in Guerrero, Mexico, 2020\u20132021"],"prefix":"10.4269","volume":"106","author":[{"given":"Daniel","family":"Nunez-Avellaneda","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine, Iowa State University, Ames, Iowa;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabian R.","family":"Villag\u00f3mez","sequence":"additional","affiliation":[{"name":"Laboratorio de Microbiolog\u00eda Molecular, Escuela Nacional de Ciencias Biol\u00f3gicas del Instituto Polit\u00e9cnico Nacional, Ciudad de M\u00e9xico, Mexico;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julio C.","family":"Villegas-Pineda","sequence":"additional","affiliation":[{"name":"Departamento de Microbiolog\u00eda y Patolog\u00eda, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, M\u00e9xico;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline","family":"Barrios-Palacios","sequence":"additional","affiliation":[{"name":"National Institute of Medical Sciences and Nutrition Salvador Zubir\u00e1n, Experimental Pathology Section, Ciudad de M\u00e9xico, Mexico;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ma. Isabel","family":"Salazar","sequence":"additional","affiliation":[{"name":"Laboratorio de Virolog\u00eda e Inmunovirolog\u00eda, Depto. Microbiolog\u00eda Escuela Nacional de Ciencias Biol\u00f3gicas Instituto Polit\u00e9cnico Nacional, Ciudad de Mexico, Mexico;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Machain-Williams","sequence":"additional","affiliation":[{"name":"Laboratorio de Arbovirologia, Centro de Investigaciones Regionales \u201cDr. Hideyo Noguchi,\u201d Universidad Autonoma de Yucatan, Merida, Yucatan, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley J.","family":"Blitvich","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Iowa State University, Ames, Iowa;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"N Engl J Med","first-page":"1708","article-title":"Clinical characteristics of coronavirus disease 2019 in China","volume":"382","year":"2020"},{"key":"b2","series-title":"Annu Rev Med","first-page":"395","article-title":"Zika, chikungunya, 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