{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T20:31:46Z","timestamp":1783024306384,"version":"3.54.6"},"reference-count":32,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4_Suppl","license":[{"start":{"date-parts":[[2022,10,11]],"date-time":"2022-10-11T00:00:00Z","timestamp":1665446400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,10,11]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Malaria control programs in Africa encounter daunting challenges that hinder progressive steps toward elimination of the disease. These challenges include widespread insecticide resistance in mosquito vectors, increasing outdoor malaria transmission, lack of vector surveillance and control tools suitable for outdoor biting vectors, weakness in malaria surveillance, and an inadequate number of skilled healthcare personnel. Ecological and epidemiological changes induced by environmental modifications resulting from water resource development projects pose additional barriers to malaria control. Cognizant of these challenges, our International Center of Excellence for Malaria Research (ICEMR) works in close collaboration with relevant government ministries and agencies to align its research efforts with the objectives and strategies of the national malaria control and elimination programs for the benefit of local communities. Our overall goal is to assess the impact of water resource development projects, shifting agricultural practices, and vector interventions on <jats:italic>Plasmodium falciparum<\/jats:italic> and <jats:italic>P. vivax<\/jats:italic> malaria in Kenya and Ethiopia. From 2017 to date, the ICEMR has advanced knowledge of malaria epidemiology, transmission, immunology, and pathogenesis, and developed tools to enhance vector surveillance and control, improved clinical malaria surveillance and diagnostic methods, and strengthened the capacity of local healthcare providers. Research findings from the ICEMR will inform health policy and strategic planning by ministries of health in their quest to sustain malaria control and achieve elimination goals.<\/jats:p>","DOI":"10.4269\/ajtmh.21-1303","type":"journal-article","created":{"date-parts":[[2022,10,13]],"date-time":"2022-10-13T21:08:20Z","timestamp":1665695300000},"page":"14-20","source":"Crossref","is-referenced-by-count":20,"title":["Enhancing Malaria Research, Surveillance, and Control in Endemic Areas of Kenya and Ethiopia"],"prefix":"10.4269","volume":"107","author":[{"given":"John I.","family":"Githure","sequence":"first","affiliation":[{"name":"Tom Mboya University College, Homa Bay, Kenya;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delenasaw","family":"Yewhalaw","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, Institute of Health, Jimma University, Jimma, Ethiopia;"},{"name":"Tropical and Infectious Diseases Research Center, Jimma University, Jimma, Ethiopia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harrysone","family":"Atieli","sequence":"additional","affiliation":[{"name":"School of Public Health and Community Development, Maseno University, Kisumu, Kenya;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Hemming-Schroeder","sequence":"additional","affiliation":[{"name":"Center for Global Health & Diseases, Case Western Reserve University, Cleveland, Ohio;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Chieh","family":"Lee","sequence":"additional","affiliation":[{"name":"Program in Public Health, University of California at Irvine, Irvine, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoming","family":"Wang","sequence":"additional","affiliation":[{"name":"Program in Public Health, University of California at Irvine, Irvine, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guofa","family":"Zhou","sequence":"additional","affiliation":[{"name":"Program in Public Health, University of California at Irvine, Irvine, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daibin","family":"Zhong","sequence":"additional","affiliation":[{"name":"Program in Public Health, University of California at Irvine, Irvine, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher L.","family":"King","sequence":"additional","affiliation":[{"name":"Center for Global Health & Diseases, Case Western Reserve University, Cleveland, Ohio;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arlene","family":"Dent","sequence":"additional","affiliation":[{"name":"Center for Global Health & Diseases, Case Western Reserve University, Cleveland, Ohio;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang Richard","family":"Mukabana","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Nairobi, Nairobi, Kenya;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teshome","family":"Degefa","sequence":"additional","affiliation":[{"name":"Department of Medical Laboratory Sciences, Institute of Health, Jimma University, Jimma, Ethiopia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuolin","family":"Hsu","sequence":"additional","affiliation":[{"name":"Center for Hydrometeorology and Remote Sensing, Department of Civil and Environmental Engineering, University of California at Irvine, Irvine, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew K.","family":"Githeko","sequence":"additional","affiliation":[{"name":"Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordon","family":"Okomo","sequence":"additional","affiliation":[{"name":"Ministry of Health, Homa Bay County, Homa Bay, Kenya;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilyana","family":"Dayo","sequence":"additional","affiliation":[{"name":"Ministry of Health, Kisumu County, Kisumu, Kenya;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kora","family":"Tushune","sequence":"additional","affiliation":[{"name":"Department of Health Management and Policy, Faculty of Public Health, Jimma University, Jimma, Ethiopia;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles O.","family":"Omondi","sequence":"additional","affiliation":[{"name":"Tom Mboya University College, Homa Bay, Kenya;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiwot S.","family":"Taffese","sequence":"additional","affiliation":[{"name":"National Malaria Program, Federal Ministry of Health, Addis Ababa, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James W.","family":"Kazura","sequence":"additional","affiliation":[{"name":"Center for Global Health & Diseases, Case Western Reserve University, Cleveland, Ohio;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guiyun","family":"Yan","sequence":"additional","affiliation":[{"name":"Program in Public Health, University of California at Irvine, Irvine, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","year":"2016"},{"key":"b2","year":"2019"},{"key":"b3","year":"2021"},{"key":"b4","year":"2016"},{"key":"b5","year":"2020"},{"key":"b6","series-title":"Parasit Vectors","first-page":"310","article-title":"Pyrethroid susceptibility of malaria vectors in four districts of western Kenya","volume":"7","year":"2014"},{"key":"b7","series-title":"Malar J","first-page":"469","article-title":"Insecticide resistance in Anopheles arabiensis from Ethiopia (2012\u20132016): a nationwide study for insecticide resistance monitoring","volume":"16","year":"2017"},{"key":"b8","series-title":"J Infect Dis","first-page":"S155","article-title":"Entomological and anthropological factors contributing to persistent malaria transmission in Kenya, Ethiopia, and Cameroon","volume":"223","year":"2021"},{"key":"b9","series-title":"Ann N Y Acad Sci","first-page":"204","article-title":"The ecology of Anopheles mosquitoes under climate change: case studies from the effects of deforestation in East African highlands","volume":"1249","year":"2012"},{"key":"b10","series-title":"Am J Trop Med Hyg","first-page":"69","article-title":"Association between land cover and habitat productivity of malaria vectors in western Kenyan highlands","volume":"74","year":"2006"},{"key":"b11","series-title":"Infect Dis Poverty","first-page":"9","article-title":"Effects of environmental modification on the diversity and positivity of Anopheline mosquito aquatic habitats at Arjo-Dedessa irrigation development site, southwest Ethiopia","volume":"9","year":"2020"},{"key":"b12","series-title":"Malar J","first-page":"69","article-title":"Achieving global malaria eradication in changing landscapes","volume":"20","year":"2021"},{"key":"b13","series-title":"J Infect Dis","first-page":"1254","article-title":"Frequent spread of Plasmodium vivax malaria maintains high genetic diversity at the Myanmar\u2013China border, without distance and landscape barriers","volume":"216","year":"2017"},{"key":"b14","series-title":"PLOS ONE","first-page":"e8022","article-title":"Ranking malaria risk factors to guide malaria control efforts in African highlands","volume":"4","year":"2009"},{"key":"b15","series-title":"Malar J","first-page":"174","article-title":"Evaluation of human-baited double net trap and human-odour-baited CDC light trap for outdoor host-seeking malaria vector surveillance in Kenya and Ethiopia","volume":"19","year":"2020"},{"key":"b16","series-title":"Parasit Vectors","first-page":"278","article-title":"Evaluation of the performance of new sticky pots for outdoor resting malaria vector surveillance in western Kenya","volume":"12","year":"2019"},{"key":"b17","series-title":"J Med Entomol","first-page":"14","article-title":"Sampling outdoor, resting Anopheles gambiae and other mosquitoes (Diptera: Culicidae) in Western Kenya with clay pots","volume":"44","year":"2007"},{"key":"b18","series-title":"Malar J","first-page":"443","article-title":"Indoor and outdoor malaria vector surveillance in western Kenya: implications for better understanding of residual transmission","volume":"16","year":"2017"},{"key":"b19","year":"2019"},{"key":"b20","series-title":"Trop Med Int Health","first-page":"37","article-title":"Efficacy and efficiency of new Bacillus thuringiensis var israelensis and Bacillus sphaericus formulations against Afrotropical anophelines in western Kenya","volume":"8","year":"2003"},{"key":"b21","series-title":"Trop Med Int Health","first-page":"1629","article-title":"Suppression of exposure to malaria vectors by an order of magnitude using microbial larvicides in rural Kenya","volume":"11","year":"2006"},{"key":"b22","series-title":"Bull World Health Organ","first-page":"655","article-title":"Integrated malaria vector control with microbial larvicides and insecticide-treated nets in western Kenya: a controlled trial","volume":"87","year":"2009"},{"key":"b23","series-title":"Parasitol Res","first-page":"1355","article-title":"Wide-scale application of Bti\/Bs biolarvicide in different aquatic habitat types in urban and peri-urban Malindi, Kenya","volume":"108","year":"2011"},{"key":"b24","series-title":"Malar J","first-page":"577","article-title":"Evaluation of long-lasting microbial larvicide for malaria vector control in Kenya","volume":"15","year":"2016"},{"key":"b25","series-title":"Parasit Vectors","first-page":"438","article-title":"Efficacy and persistence of long-lasting microbial larvicides against malaria vectors in western Kenya highlands","volume":"11","year":"2018"},{"key":"b26","series-title":"Cochrane Database Syst Rev","first-page":"CD008923","article-title":"Mosquito larval source management for controlling malaria","volume":"8","year":"2013"},{"key":"b27","series-title":"Am J Trop Med Hyg","first-page":"1173","article-title":"An adaptive intervention trial design for finding the optimal integrated strategies for malaria control and elimination in Africa: a model simulation study","volume":"105","year":"2021"},{"key":"b28","series-title":"Test, Treat, Track: Scaling Up Diagnostic Testing, Treatment and Surveillance for Malaria","year":"2012"},{"key":"b29","series-title":"Nat Microbiol","first-page":"1289","article-title":"Plasmodium falciparum is evolving to escape malaria rapid diagnostic tests in Ethiopia","volume":"6","year":"2021"},{"key":"b30","series-title":"Infect Dis Poverty","first-page":"103","article-title":"Malaria epidemiology and interventions in Ethiopia from 2001 to 2016","volume":"7","year":"2018"},{"key":"b31","series-title":"Trials","first-page":"665","article-title":"Adaptive interventions for optimizing malaria control: an implementation study protocol for a block-cluster randomized, sequential multiple assignment trial","volume":"21","year":"2020"},{"key":"b32","series-title":"Sci Rep","first-page":"10150","article-title":"Predicting distribution of malaria vector larval habitats in Ethiopia by integrating distributed hydrologic modeling with remotely sensed data","volume":"11","year":"2021"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/107\/4_Suppl\/article-p14.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/107\/4_Suppl\/article-p14.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/107\/4_Suppl\/article-p14.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,13]],"date-time":"2022-10-13T21:10:06Z","timestamp":1665695406000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/107\/4_Suppl\/article-p14.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,11]]},"references-count":32,"journal-issue":{"issue":"4_Suppl"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.21-1303","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,11]]}}}