{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T19:52:06Z","timestamp":1791748326718,"version":"4.3.4"},"reference-count":19,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,17]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>In Canada, a substantial proportion of migrants come from strongyloidiasis-endemic regions. Systematic screening for <jats:italic>Strongyloides<\/jats:italic> is not performed in immunocompromised patients in whom this infection could be potentially fatal. We aim to assess the level of <jats:italic>Strongyloides<\/jats:italic> awareness and knowledge among Canadian physicians caring for immunocompromised patients and identify factors currently associated with screening. Using an online survey distributed through Canadian medical associations, we collected information on physicians\u2019 demographics, practice setting, overall awareness and knowledge of <jats:italic>Strongyloides<\/jats:italic>, and current practices. Descriptive analysis and logistic regression models were performed to identify the factors associated with <jats:italic>Strongyloides<\/jats:italic> screening. Nineteen national and provincial medical associations agreed to participate. Between November 2020 and August 2021, 368 of 5,194 (7%) physicians that were contacted responded to our survey. Quebec (46%) and Ontario (24%) were the most responsive. Sixty-nine percent of respondents practiced medicine in academic settings. Infectious disease (ID) specialists\/medical microbiologists (38%) followed by nephrologists (33%) were the most represented. Most respondents (95%) had heard about <jats:italic>Strongyloides.<\/jats:italic> However, 36% of non-ID specialists considered themselves unfamiliar. Forty percent of respondents did not or rarely performed screening for strongyloidiasis in high-risk populations. Screening was associated with younger-aged physicians (odds ratio [OR] 2.35; 95% confidence interval [CI] 1.07\u20135.18), physicians who frequently served migrants (OR 3.33; 95% CI 1.44\u20137.66), or those who had training in global health and ID\/medical microbiology (OR 3.71; 95% CI 1.21\u201311.34 and OR 46.42; 95% CI 15.89\u2013135.59, respectively). Our survey suggests a general lack of knowledge of <jats:italic>Strongyloides<\/jats:italic> among Canadian physicians that is associated with low rates of screening in high-risk populations.<\/jats:p>","DOI":"10.4269\/ajtmh.22-0109","type":"journal-article","created":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T13:13:18Z","timestamp":1657026798000},"page":"359-366","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of Strongyloides Awareness and Knowledge among Canadian Physicians Caring for Patients At Risk for Severe Strongyloidiasis: A National Cross-sectional Survey"],"prefix":"10.4269","volume":"107","author":[{"given":"Samuel","family":"De l\u2019\u00c9toile-Morel","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases, McGill University Health Centre, Montreal, Canada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faheel","family":"Naeem","sequence":"additional","affiliation":[{"name":"J. D. MacLean Centre for Tropical Diseases at McGill University, Montreal, Canada;"},{"name":"Research Institute of the McGill University Health Centre, Montreal, Canada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Alghounaim","sequence":"additional","affiliation":[{"name":"The Montreal Children\u2019s Hospital, Division of Infectious Diseases, Department of Pediatrics, McGill University Health Centre, Montreal, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makeda","family":"Semret","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases, McGill University Health Centre, Montreal, Canada;"},{"name":"J. D. MacLean Centre for Tropical Diseases at McGill University, Montreal, Canada;"},{"name":"Research Institute of the McGill University Health Centre, Montreal, Canada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cedric P.","family":"Yansouni","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases, McGill University Health Centre, Montreal, Canada;"},{"name":"J. D. MacLean Centre for Tropical Diseases at McGill University, Montreal, Canada;"},{"name":"Research Institute of the McGill University Health Centre, Montreal, Canada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Libman","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases, McGill University Health Centre, Montreal, Canada;"},{"name":"J. D. MacLean Centre for Tropical Diseases at McGill University, Montreal, Canada;"},{"name":"Research Institute of the McGill University Health Centre, Montreal, Canada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sapha","family":"Barkati","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Infectious Diseases, McGill University Health Centre, Montreal, Canada;"},{"name":"J. D. MacLean Centre for Tropical Diseases at McGill University, Montreal, Canada;"},{"name":"Research Institute of the McGill University Health Centre, Montreal, Canada;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Pathogens","article-title":"The global prevalence of Strongyloides stercoralis infection","volume":"9","year":"2020"},{"key":"b2","series-title":"Am J Trop Med Hyg","doi-asserted-by":"publisher","first-page":"645","DOI":"10.4269\/ajtmh.16-0923","article-title":"Evidence-based guidelines for screening and management of strongyloidiasis in non-endemic countries","volume":"97","year":"2017"},{"key":"b3","series-title":"Can Commun Dis Rep","doi-asserted-by":"publisher","first-page":"12","DOI":"10.14745\/ccdr.v42i01a03","article-title":"CATMAT statement on disseminated strongyloidiasis: prevention, assessment and management guidelines","volume":"42","year":"2016"},{"key":"b4","series-title":"Curr Opin Infect Dis","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1097\/QCO.0b013e32833df718","article-title":"Strongyloides stercoralis: there but not seen","volume":"23","year":"2010"},{"key":"b5","series-title":"Am J Med","doi-asserted-by":"publisher","first-page":"545.e1","DOI":"10.1016\/j.amjmed.2006.05.072","article-title":"Maltreatment of Strongyloides infection: case series and worldwide physicians-in-training survey","volume":"120","year":"2007"},{"key":"b6","series-title":"Lancet Glob Health","doi-asserted-by":"publisher","first-page":"e236","DOI":"10.1016\/S2214-109X(18)30490-X","article-title":"Prevalence of strongyloidiasis and schistosomiasis among migrants: a systematic review and meta-analysis","volume":"7","year":"2019"},{"key":"b7","year":"2017"},{"key":"b8","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1056\/NEJMoa2021436","article-title":"Dexamethasone in hospitalized patients with COVID-19","volume":"384","year":"2021"},{"key":"b9","series-title":"Infection","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1007\/s15010-015-0799-1","article-title":"Strongyloides stercoralis hyperinfection syndrome: a case series and a review of the literature","volume":"43","year":"2015"},{"key":"b10","series-title":"BMJ Open","doi-asserted-by":"publisher","first-page":"e007166","DOI":"10.1136\/bmjopen-2014-007166","article-title":"National survey of physicians to determine the effect of unconditional incentives on response rates of physician postal surveys","volume":"5","year":"2015"},{"key":"b11","series-title":"Intern Med J.","article-title":"A mixed-method analysis of screening for Strongyloides stercoralis prior to immunosuppression: a problem of limited bandwidth?","year":"2020"},{"key":"b12","year":"2019"},{"key":"b13","series-title":"N Engl J Med","first-page":"693","article-title":"Dexamethasone in hospitalized patients with COVID-19","volume":"384","year":"2020"},{"key":"b14","series-title":"Am J Trop Med Hyg","doi-asserted-by":"publisher","first-page":"1590","DOI":"10.4269\/ajtmh.20-0699","article-title":"Case report: disseminated strongyloidiasis in a patient with COVID-19","volume":"103","year":"2020"},{"key":"b15","series-title":"IDCases","doi-asserted-by":"publisher","first-page":"e01192","DOI":"10.1016\/j.idcr.2021.e01192","article-title":"Corticosteroids in COVID-19 pandemic have the potential to unearth hidden burden of strongyloidiasis","volume":"25","year":"2021"},{"key":"b16","series-title":"Infection","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1007\/s15010-020-01522-4","article-title":"Strongyloides infection manifested during immunosuppressive therapy for SARS-CoV-2 pneumonia","volume":"49","year":"2021"},{"key":"b17","series-title":"Clinics (S\u00e3o Paulo)","doi-asserted-by":"publisher","first-page":"e3528","DOI":"10.6061\/clinics\/2021\/e3528","article-title":"COVID-19 and strongyloidiasis: what to expect from this coinfection?","volume":"76","year":"2021"},{"key":"b18","series-title":"J Travel Med.","article-title":"Strongyloidiasis in immunocompromised migrants to non-endemic countries in the era of COVID-19: what is the role for presumptive ivermectin?","year":"2021"},{"key":"b19","series-title":"JAMA","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1001\/jama.2020.13170","article-title":"COVID-19 and dexamethasone: a potential strategy to avoid steroid-related Strongyloides hyperinfection","volume":"324","year":"2020"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/107\/2\/article-p359.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/107\/2\/article-p359.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/107\/2\/article-p359.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T13:14:48Z","timestamp":1660742088000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/107\/2\/article-p359.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,17]]},"references-count":19,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.22-0109","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,17]]}}}