{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T08:59:56Z","timestamp":1765357196646},"reference-count":27,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,10,12]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>The immunosuppressive effect of methotrexate has rarely been associated with reactivation of cutaneous leishmaniasis. Here we present a case of a cutaneous leishmaniasis patient with atypical clinical symptoms without splenomegaly but with cutaneous manifestations after treatment of rheumatoid arthritis with methotrexate and blood recovery of the parasite. Next-generation sequencing was used to identify <jats:italic>Leishmania infantum chagasi<\/jats:italic> in the patient\u2019s blood sample.<\/jats:p>","DOI":"10.4269\/ajtmh.22-0180","type":"journal-article","created":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T14:26:01Z","timestamp":1662474361000},"page":"785-788","source":"Crossref","is-referenced-by-count":5,"title":["Case Report: Cutaneous Leishmaniasis in a Rheumatoid Arthritis Patient Receiving Methotrexate"],"prefix":"10.4269","volume":"107","author":[{"given":"Valdir Sabbaga","family":"Amato","sequence":"first","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Instituto de Medicina Tropical de S\u00e3o Paulo, Laborat\u00f3rio de Parasitologia, S\u00e3o Paulo, S\u00e3o Paulo, Brazil;"},{"name":"Universidade de S\u00e3o Paulo, Faculdade de Medicina, Departamento de Mol\u00e9stias Infecciosas e Parasit\u00e1rias, S\u00e3o Paulo, S\u00e3o Paulo, 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