{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T05:28:29Z","timestamp":1792214909122,"version":"4.4.0"},"reference-count":94,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"5","license":[{"start":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T00:00:00Z","timestamp":1668384000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11,14]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>The objective of this study was to determine the etiology of febrile illnesses among patients from October 1, 1993 through September 30, 1999, in the urban community of Iquitos in the Amazon River Basin of Peru. Epidemiological and clinical data as well as blood samples were obtained from consenting patients at hospitals, health clinics and private residences. Samples were tested for arboviruses in cell cultures and for IgM and IgG antibodies by ELISA. Blood smears were examined for malaria, and sera were tested for antibodies to <jats:italic>Leptospira <\/jats:italic>spp. by ELISA and microscopic agglutination. Among 6,607 febrile patients studied, dengue viruses caused 14.6% of the cases, and Venezuelan equine encephalitis virus caused 2.5%, Oropouche virus 1.0%, Mayaro virus 0.4%, and other arboviruses caused 0.2% of the cases. Also, 22.9% of 4,844 patients tested were positive for malaria, and of 400 samples tested, 9% had evidence of acute leptospirosis. Although the study was not designed to assess the importance of these pathogens as a cause of human morbidity in the total population, these results indicate that arboviruses, leptospirosis, and malaria were the cause of approximately 50% of the febrile cases. Although the arboviruses that were diagnosed can produce asymptomatic infections, our findings increased the overall understanding of the relative health burden of these infections, as well as baseline knowledge needed for designing and implementing further studies to better assess the health impact and threat of these pathogens in the Amazon Basin of Peru.<\/jats:p>","DOI":"10.4269\/ajtmh.22-0259","type":"journal-article","created":{"date-parts":[[2022,9,26]],"date-time":"2022-09-26T13:39:12Z","timestamp":1664199552000},"page":"1114-1128","source":"Crossref","is-referenced-by-count":32,"title":["Etiologies of Acute Undifferentiated Febrile Illnesses in and near Iquitos from 1993 to 1999 in the Amazon River Basin of Peru"],"prefix":"10.4269","volume":"107","author":[{"given":"Douglas M.","family":"Watts","sequence":"first","affiliation":[{"name":"U.S. Naval Medical Research Unit No. 6, Lima, Peru;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin L.","family":"Russell","sequence":"additional","affiliation":[{"name":"U.S. Naval Medical Research Unit No. 6, Lima, Peru;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark T.","family":"Wooster","sequence":"additional","affiliation":[{"name":"U.S. Naval Medical Research Unit No. 6, Lima, Peru;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trueman W.","family":"Sharp","sequence":"additional","affiliation":[{"name":"U.S. Naval Medical Research Unit No. 6, Lima, Peru;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy C.","family":"Morrison","sequence":"additional","affiliation":[{"name":"University of California, Davis School of Veterinary Medicine Department of Pathology, Microbiology, and Immunology, Davis, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tad J.","family":"Kochel","sequence":"additional","affiliation":[{"name":"U.S. Naval Medical Research Unit No. 6, Lima, Peru;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian T.","family":"Bautista","sequence":"additional","affiliation":[{"name":"U.S. Naval Medical Research Unit No. 6, Lima, Peru;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karla","family":"Block","sequence":"additional","affiliation":[{"name":"U.S. Naval Medical Research Unit No. 6, Lima, Peru;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Guevara","sequence":"additional","affiliation":[{"name":"U.S. Naval Medical Research Unit No. 6, Lima, Peru;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Aguilar","sequence":"additional","affiliation":[{"name":"World Reference Center for Emerging Viruses and Arboviruses University of Texas Medical Branch, Galveston, Texas;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro M.","family":"Palermo","sequence":"additional","affiliation":[{"name":"U.S. Naval Medical Research Unit No. 6, Lima, Peru;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Calampa","sequence":"additional","affiliation":[{"name":"Peruvian Ministry of Health, Loreto Health Subregion, Iquitos, Peru;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin R.","family":"Porter","sequence":"additional","affiliation":[{"name":"U.S. Naval Medical Research Center, Silver Spring, Maryland;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Curtis G.","family":"Hayes","sequence":"additional","affiliation":[{"name":"U.S. Naval Medical Research Center, Silver Spring, Maryland;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott C.","family":"Weaver","sequence":"additional","affiliation":[{"name":"World Reference Center for Emerging Viruses and Arboviruses University of Texas Medical Branch, Galveston, Texas;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelia Travassos","family":"de Rosa","sequence":"additional","affiliation":[{"name":"World Reference Center for Emerging Viruses and Arboviruses University of Texas Medical Branch, Galveston, Texas;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph M.","family":"Vinetz","sequence":"additional","affiliation":[{"name":"World Reference Center for Emerging Viruses and Arboviruses University of Texas Medical Branch, Galveston, Texas;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert E.","family":"Shope","sequence":"additional","affiliation":[{"name":"World Reference Center for Emerging Viruses and Arboviruses University of Texas Medical Branch, Galveston, Texas;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Gotuzzo","sequence":"additional","affiliation":[{"name":"Department of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilda","family":"Guzman","sequence":"additional","affiliation":[{"name":"World Reference Center for Emerging Viruses and Arboviruses University of Texas Medical Branch, Galveston, Texas;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert B.","family":"Tesh","sequence":"additional","affiliation":[{"name":"World Reference Center for Emerging Viruses and Arboviruses University of Texas Medical Branch, Galveston, Texas;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Arboviruses: Molecular Biology, Evolution and Control","first-page":"1","author":"Gubler","year":"2016"},{"key":"b2","series-title":"International Catalogue of Arboviruses","author":"Karabastsos","year":"1985"},{"key":"b3","series-title":"Arboviruses: Molecular Biology, Evolution and Control","first-page":"9","author":"Arrigo","year":"2016"},{"key":"b4","series-title":"Trans R Soc Trop Med Hyg","first-page":"76","article-title":"Study of coinciding foci of malaria and leptospirosis in the Peruvian Amazon area","volume":"72","author":"Sulzer","year":"1978"},{"key":"b5","series-title":"Am J Trop Med Hyg","first-page":"53","article-title":"An outbreak of leptospirosis among Peruvian military recruits","volume":"69","author":"Russell","year":"2003"},{"key":"b6","series-title":"N Engl J Med","first-page":"497","article-title":"An efficacy trial of doxycycline chemoprophylaxis against leptospirosis","volume":"310","author":"Takafuji","year":"1984"},{"key":"b7","series-title":"Emerg Infect Dis","first-page":"1455","article-title":"Leptospirosis: skin wounds and control strategies, Thailand, 1999","volume":"8","author":"Phraisuwan","year":"2002"},{"key":"b8","series-title":"The Arboviruses: Epidemiology and Ecology","first-page":"223","author":"Gubler","year":"1988"},{"key":"b9","series-title":"The Arboviruses: Epidemiology and Ecology","first-page":"203","author":"Walton","year":"1988"},{"key":"b10","series-title":"The Arboviruses: Epidemiology and Ecology","first-page":"1","author":"LeDuc","year":"1988"},{"key":"b11","series-title":"The Arboviruses: Epidemiology and Ecology","first-page":"137","author":"Pinheiro","year":"1988"},{"key":"b12","series-title":"The Arboviruses: Epidemiology and Ecology","first-page":"77","author":"Iversson","year":"1988"},{"key":"b13","series-title":"The Arboviruses: Epidemiology and Ecology","first-page":"139","author":"Monath","year":"1988"},{"key":"b14","series-title":"Cad Saude Publica","first-page":"155","article-title":"Inadequate management of natural ecosystem in the Brazilian Amazon region results in the emergence and reemergence of arboviruses","volume":"17S","author":"Vasconcelos","year":"2001"},{"key":"b15","series-title":"An Overview of Arbovirology in Brazil and Neighboring Countries","first-page":"72","author":"Vasconcelos","year":"1998"},{"key":"b16","series-title":"Bull Pan Am Health Organ","first-page":"172","article-title":"A continuing focus of yellow fever in the Apurimac River Valley, Ayacucho, Peru, and the first isolation of yellow fever virus in that country","volume":"84","author":"Mendez","year":"1984"},{"key":"b17","series-title":"Emerg Infect Dis","first-page":"926","article-title":"Enzootic transmission of yellow fever virus in Peru","volume":"9","author":"Bryant","year":"2003"},{"key":"b18","first-page":"198","author":"Madalengoitia","year":"1972"},{"key":"b19","first-page":"302","author":"Trapido","year":"1971"},{"key":"b20","series-title":"Am J Epidemiol","first-page":"286","article-title":"Antigenic variants of Venezuelan equine encephalitis virus: their geographic distribution and epidemiologic significance","volume":"89","author":"Young","year":"1969"},{"key":"b21","series-title":"Bull Pan Am Health Organ","first-page":"201","article-title":"First documented outbreak of dengue in the Peruvian Amazon region","volume":"26","author":"Phillips","year":"1992"},{"key":"b22","series-title":"Rev Farmacol Terap (Lima)","first-page":"12","article-title":"Fiebre de Oropouche en Iquitos: reporte preliminar de 5 casos","volume":"2","author":"Chavez","year":"1992"},{"key":"b23","series-title":"Am J Epidemiol","first-page":"347","article-title":"Ecologic studies of Venezuelan encephalitis virus in Peru during 1970\u20131971","volume":"101","author":"Scherer","year":"1975"},{"key":"b24","series-title":"Bull Pan Am Health Organ","first-page":"19","article-title":"The first isolations of eastern equine encephalitis, Group C, and Guama group arboviruses from the Peruvian Amazon region of Western South America","volume":"9","author":"Scherer","year":"1975"},{"key":"b25","series-title":"Am J Epidemiol","first-page":"356","article-title":"Antigenic and biologic characteristics of Venezuelan encephalitis virus strains including a possible new subtype, isolated from the Amazon region of Peru in 1971","volume":"101","author":"Scherer","year":"1975"},{"key":"b26","series-title":"J Clin Microbiol","first-page":"578","article-title":"Comparisons of Venezuelan encephalitis virus strains by hemagglutination-inhibition tests with chicken antibodies","volume":"6","author":"Scherer","year":"1977"},{"key":"b27","series-title":"Bull Pan Am Health Organ","first-page":"272","article-title":"Study of VE virus and isolations of SLE, EE and group C and Guama group arboviruses in the Amazon region of Peru, 1975","volume":"13","author":"Scherer","year":"1979"},{"key":"b28","series-title":"Am J Trop Med Hyg","first-page":"871","article-title":"An unusual strain of Venezuelan encephalitis virus existing sympatrically with subtype ID strains in a Peruvian rain forest","volume":"32","author":"Scherer","year":"1983"},{"key":"b29","series-title":"Bull World Health Organ","first-page":"451","article-title":"Arbovirus antibody neutralization with Peruvian sera in Vero cell cultures","volume":"46","author":"Buckley","year":"1972"},{"key":"b30","series-title":"Bol Oficina Sanit Panam","first-page":"25","article-title":"Arbovirus antibody survey on sera from residents of eastern Peru","volume":"7","author":"Madalengoitia","year":"1973"},{"key":"b31","series-title":"Am J Trop Med Hyg","first-page":"661","article-title":"Venezuelan equine encephalitis viral infection among Peruvian military troops in the Amazon River Basin of Peru","volume":"56","author":"Watts","year":"1997"},{"key":"b32","series-title":"Am J Trop Med Hyg","first-page":"41","article-title":"Identification and genetic analysis of Panama-genotype Venezuelan equine encephalitis virus subtype ID in Peru","volume":"58","author":"Oberste","year":"1998"},{"key":"b33","series-title":"Am J Trop Med Hyg","first-page":"35","article-title":"Venezuelan equine encephalitis febrile cases among human in the Peruvian Amazon River Basin","volume":"58","author":"Watts","year":"1998"},{"key":"b34","series-title":"Am J Trop Med Hyg","first-page":"459","article-title":"The epidemiology of dengue virus infection among urban, jungle, and rural populations in the Amazon region of Peru","volume":"55","author":"Hayes","year":"1996"},{"key":"b35","series-title":"Lancet","first-page":"1431","article-title":"Failure of secondary dengue 2 genotype I infection to cause dengue hemorrhagic fever","volume":"354","author":"Watts","year":"1999"},{"key":"b36","series-title":"PLoS Negl Trop Dis","first-page":"e349","article-title":"Venezuelan equine encephalitis virus in Iquitos, Peru: urban transmission of a sylvatic strain","volume":"2","author":"Morrison","year":"2008"},{"key":"b37","series-title":"Diagnostic Procedures for Viral, Rickettsial, and Chlamydial Infections","first-page":"797","author":"Beaty","year":"1989"},{"key":"b38","series-title":"Am J Trop Med Hyg","first-page":"830","article-title":"Dengue virus specific and flavivirus group determinants identified with monoclonal antibodies by indirect immunofluorescence","volume":"31","author":"Henchal","year":"1982"},{"key":"b39","series-title":"Virology","first-page":"8","article-title":"Monoclonal antibodies distinguish between wild and vaccine strains of yellow fever virus by neutralization, hemagglutination inhibition, and immune precipitation of the virus envelope protein","volume":"125","author":"Schlesinger","year":"1983"},{"key":"b40","series-title":"Virology","first-page":"269","article-title":"Antigenic analysis of the surface glycoproteins of a Venezuelan equine encephalomyelitis virus (TC-83) using monoclonal antibodies","volume":"118","author":"Roehrig","year":"1982"},{"key":"b41","series-title":"Clin Infect Dis","first-page":"67","article-title":"Mayaro virus disease: an emerging mosquito-borne zoonosis in tropical South America","volume":"28","author":"Tesh","year":"1999"},{"key":"b42","series-title":"Appl Microbiol","first-page":"976","article-title":"Improved microtechnique for the leptospiral microscopic agglutination test","volume":"25","author":"Cole","year":"1973"},{"key":"b43","series-title":"Applied Logistic Regression","author":"Hosmer","year":"1989"},{"key":"b44","series-title":"Computer Programs for Epidemiologic Analysis","author":"Gahlinger","year":"1997"},{"key":"b45","series-title":"J Med Ent","first-page":"891","article-title":"Isolation of viruses from mosquitoes collected in the Amazon Basin region of Peru","volume":"42","author":"Turell","year":"2005"},{"key":"b46","series-title":"Am J Trop Med Hyg","first-page":"293","article-title":"Endemic eastern equine encephalitis in the Amazon region of Peru","volume":"76","author":"Aguilar","year":"2007"},{"key":"b47","series-title":"Virus Res","first-page":"25","article-title":"Jatobal virus is a reassortant containing the small RNA of Oropouche virus","volume":"77","author":"Saeed","year":"2001"},{"key":"b48","series-title":"Mem Inst Oswaldo Cruz","first-page":"161","article-title":"Jatobal virus antigenic characterization by ELISA and neutralization test using EIA as indicator on tissue culture","volume":"83","author":"Figueiredo","year":"1989"},{"key":"b49","series-title":"Lancet","first-page":"1589","article-title":"Diagnosis of viral disease","volume":"361","author":"Vasconcelos","year":"2003"},{"key":"b50","series-title":"Am J Trop Med Hyg","first-page":"1066","article-title":"The complex relationship between weather and dengue virus transmission in Thailand","volume":"89","author":"Campbell","year":"2013"},{"key":"b51","series-title":"Proc Natl Acad Sci","first-page":"E2694","article-title":"Time-varying, serotype-specific force of infection estimates for dengue virus","volume":"111","author":"Reiner","year":"2014"},{"key":"b52","series-title":"Am J Trop Med Hyg","first-page":"860","article-title":"An outbreak of Venezuelan encephalitis in man in the Panama Canal Zone","volume":"19","author":"Franck","year":"1970"},{"key":"b53","series-title":"Am J Trop Med Hyg","first-page":"432","article-title":"Recovery of Venezuelan equine encephalomyelitis virus in Panama. A fatal case in man","volume":"17","author":"Johnson","year":"1968"},{"key":"b54","series-title":"Am J Trop Med Hyg","first-page":"329","article-title":"Ten clinical cases of human infection with Venezuelan equine encephalomyelitis virus, subtype 1-D","volume":"28","author":"Dietz","year":"1979"},{"key":"b55","series-title":"Am J Trop Med Hyg","first-page":"148","article-title":"Oropouche virus transmission in the Amazon Basin of Peru","volume":"56","author":"Watts","year":"1997"},{"key":"b56","series-title":"Am J Trop Med Hyg","first-page":"149","article-title":"Oropouche virus I. A review of clinical, epidemiological, and ecological findings","volume":"30","author":"Pinheiro","year":"1981"},{"key":"b57","series-title":"J Gen Virol","first-page":"743","article-title":"Nucleotide sequence determination and phylogeny of the nucleocapsid gene of oropouche virus","volume":"81","author":"Saeed","year":"2000"},{"key":"b58","series-title":"Am J Trop Med Hyg","first-page":"674","article-title":"An outbreak of Mayaro virus disease in Belterra, Brazil. I. Clinical and virological findings","volume":"30","author":"Pinherio","year":"1981"},{"key":"b59","author":"Pinheiro","year":"1994"},{"key":"b60","series-title":"Am J Trop Med Hyg","first-page":"452","article-title":"Mayaro virus in French Guiana: isolation, identification, and seroprevalence","volume":"59","author":"Talarmin","year":"1998"},{"key":"b61","series-title":"The Arboviruses: Epidemiology and Ecology","first-page":"37","author":"Shope","year":"1988"},{"key":"b62","series-title":"Arboviruses: Molecular Biology, Evolution and Control","first-page":"61","author":"Friedrich","year":"2008"},{"key":"b63","series-title":"Malaria J","first-page":"303","article-title":"The history of 20th century malaria control in Peru","volume":"12","author":"Griffing","year":"2013"},{"key":"b64","series-title":"PLoS Negl Trop Dis","first-page":"e213","article-title":"Human leptospirosis caused by a new, antigenically unique Leptospira associated with a Rattus species reservoir in the Peruvian Amazon","volume":"2","author":"Matthias","year":"2008"},{"key":"b65","series-title":"PLoS Negl Trop Dis","first-page":"e670","article-title":"Epidemiology of dengue virus in Iquitos, Peru 1999 to 2005: interepidemic and epidemic patterns of transmission","volume":"4","author":"Morrison","year":"2010"},{"key":"b66","series-title":"PLoS Negl Trop Dis","first-page":"e787","article-title":"NMRCD Febrile Surveillance Working Group. Arboviral etiologies of acute febrile illnesses in Western South America, 2000\u20132007","volume":"4","author":"Forshey","year":"2010"},{"key":"b67","series-title":"Proc Natl Acad Sci USA","first-page":"994","article-title":"House-to-house human movement drives dengue virus transmission","volume":"110","author":"Stoddard","year":"2013"},{"key":"b68","series-title":"Utility of the Tourniquet Test for Diagnoses of Dengue Fever in Iquitos, Peru, 2000\u20132010","author":"Vilcarromero","year":"2011"},{"key":"b69","series-title":"PLoS Negl Trop Dis","first-page":"e3003","article-title":"Long-term and seasonal dynamics of dengue in Iquitos, Peru","volume":"8","author":"Stoddard","year":"2014"},{"key":"b70","series-title":"PLoS Negl Trop Dis","first-page":"e0004398","article-title":"Incomplete protection against dengue virus type 2 re-infection in Peru","volume":"10","author":"Forshey","year":"2016"},{"key":"b71","series-title":"PLoS Negl Trop Dis","first-page":"e1472","article-title":"Spatial dimensions of dengue virus transmission across interepidemic and epidemic periods in Iquitos, Peru (1999\u20132003)","volume":"6","author":"Liebman","year":"2012"},{"key":"b72","series-title":"PLoS Negl Trop Dis","first-page":"e0005429","article-title":"The relationship between entomological indicators of Aedes aegypti abundance and dengue virus infection","volume":"11","author":"Cromwell","year":"2017"},{"key":"b73","series-title":"PLoS Negl Trop Dis","first-page":"e3038","article-title":"Shifting patterns of Aedes aegypti fine scale spatial clustering in Iquitos, Peru","volume":"8","author":"LaCon","year":"2014"},{"key":"b74","series-title":"J Med Entomol","first-page":"1123","article-title":"Temporal and geographic patterns of Aedes aegypti (Diptera: Culicidae) production in Iquitos, Peru","volume":"41","author":"Morrison","year":"2004"},{"key":"b75","series-title":"Am J Trop Med Hyg","first-page":"494","article-title":"Characteristics of the spatial pattern of the dengue vector, Aedes aegypti, in Iquitos, Peru","volume":"69","author":"Getis","year":"2003"},{"key":"b76","series-title":"Emerg Infect Dis","first-page":"2077","article-title":"Heterogeneity of dengue illness in community-based prospective study, Iquitos, Peru","volume":"26","author":"Elson","year":"2020"},{"key":"b77","series-title":"PLoS Negl Trop Dis","first-page":"e0007756","article-title":"Dengue illness impacts daily human mobility patterns in Iquitos, Peru","volume":"13","author":"Schaber","year":"2019"},{"key":"b78","series-title":"bioRxiv medRxiv","article-title":"Efficacy of a spatial repellent for control of Aedes-borne virus transmission: a cluster randomized trial in Iquitos, Peru","author":"Morrison","year":"2021"},{"key":"b79","series-title":"PLoS Negl Trop Dis","first-page":"e0008097","article-title":"The impact of insecticide treated curtains on dengue virus transmission: a cluster randomized trial in Iquitos, Peru","volume":"14","author":"Lenhart","year":"2020"},{"key":"b80","series-title":"PLoS Negl Trop Dis","first-page":"e0006378","article-title":"Efficacy of Aedes aegypti control by indoor ultra low volume (ULV) insecticide spraying in Iquitos, Peru","volume":"12","author":"Gunning","year":"2018"},{"key":"b81","series-title":"PLOS Comput Biol","first-page":"e1007743","article-title":"Optimizing the deployment of ultra-low volume and targeted indoor residual spraying for dengue outbreak response","volume":"16","author":"Cavany","year":"2020"},{"key":"b82","series-title":"Trop Med Int Health","first-page":"1143","article-title":"Reducing costs and operational constraints of dengue vector control by targeting productive breeding places: a multi-country non-inferiority cluster randomized trial","volume":"14","author":"Tun-Lin","year":"2009"},{"key":"b83","series-title":"Emerg Infect Dis","first-page":"1815","article-title":"2010. Dengue virus serotype 4, northeastern Peru, 2008","volume":"15","author":"Forshey","year":"2009"},{"key":"b84","series-title":"Am J Trop Med Hyg","first-page":"714","article-title":"Guaroa virus infection among humans in Bolivia and Peru","volume":"83","author":"Aguilar","year":"2010"},{"key":"b85","series-title":"Emerg Infect Dis","first-page":"731","article-title":"Guaroa virus and Plasmodium vivax co-infections, Peruvian Amazon","volume":"26","author":"Siles","year":"2020"},{"key":"b86","series-title":"PLoS Negl Trop Dis","first-page":"e1315","article-title":"Iquitos virus: a novel reassortant orthobunyavirus associated with human illness in Peru","volume":"5","author":"Aguilar","year":"2011"},{"key":"b87","series-title":"Emerg Infect Dis","first-page":"781","article-title":"Itaya virus, a novel orthobunyavirus associated with human febrile illness, Peru","volume":"21","author":"Hontz","year":"2015"},{"key":"b88","series-title":"PLoS Negl Trop Dis","first-page":"e0006708","article-title":"\u201cZika is everywhere\u201d: a qualitative exploration of knowledge, attitudes and practices towards Zika virus among women of reproductive age in Iquitos, Peru","volume":"12","author":"Weldon","year":"2018"},{"key":"b89","year":"2017"},{"key":"b90","series-title":"Am J Trop Med Hyg","first-page":"683","article-title":"Epidemiology of spotted fever group and typhus group rickettsial infection in the Amazon basin of Peru","volume":"82","author":"Forshey","year":"2010"},{"key":"b91","series-title":"PLoS Negl Trop Dis","first-page":"e0004843","article-title":"Rickettsial disease in the Peruvian Amazon Basin","volume":"10","author":"Kocher","year":"2016"},{"key":"b92","series-title":"PLoS Negl Trop Dis","first-page":"e0004440","article-title":"Identification and genomic analysis of a novel Group C orthobunyavirus isolated from a mosquito captured near Iquitos, Peru","volume":"10","author":"Treangen","year":"2016"},{"key":"b93","series-title":"Antiviral Res","first-page":"328","article-title":"Present and future arboviral threats","volume":"85","author":"Weaver","year":"2010"},{"key":"b94","series-title":"BMJ","first-page":"m4385","article-title":"Emerging arboviruses in the urbanized Amazon rainforest","volume":"371","author":"Lowe","year":"2020"}],"container-title":["The American Journal of Tropical Medicine and Hygiene"],"original-title":[],"link":[{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/107\/5\/article-p1114.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/107\/5\/article-p1114.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.ajtmh.org\/downloadpdf\/journals\/tpmd\/107\/5\/article-p1114.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T17:08:52Z","timestamp":1668618532000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ajtmh.org\/view\/journals\/tpmd\/107\/5\/article-p1114.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,14]]},"references-count":94,"journal-issue":{"issue":"5"},"URL":"https:\/\/doi.org\/10.4269\/ajtmh.22-0259","relation":{},"ISSN":["0002-9637","1476-1645"],"issn-type":[{"value":"0002-9637","type":"print"},{"value":"1476-1645","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,14]]}}}