{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T00:14:36Z","timestamp":1715818476388},"reference-count":20,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"4","license":[{"start":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T00:00:00Z","timestamp":1665532800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,10,12]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>To assess appropriate drug treatment of parasitic diseases in the United States, we examined the treatment rates of 11 selected parasitic infections with standard-of-care prescription drugs and compared them to the treatment rates of two more common bacterial infections (<jats:italic>Clostridioides difficile<\/jats:italic> and streptococcal pharyngitis). We used the 2013 to 2019 IBM<jats:sup>\u00ae<\/jats:sup> MarketScan<jats:sup>\u00ae<\/jats:sup> Commercial Claims and Encounters and MarketScan<jats:sup>\u00ae<\/jats:sup> Multi-State Medicaid databases, which included up to 7 years of data for approximately 88 million and 17 million individuals, respectively, to estimate treatment rates of each infection. The number of patients diagnosed with each parasitic infection varied from 57 to 5,266, and from 12 to 2,018, respectively, across the two databases. Treatment rates of 10 of 11 selected parasitic infections (range, 0\u201356%) were significantly less than those for streptococcal pharyngitis and <jats:italic>Clostridioides difficile<\/jats:italic> (range, 65\u201385%); giardiasis treatment (64%) was comparable to <jats:italic>Clostridioides difficile<\/jats:italic> (65%) in patients using Medicaid. Treatment rates for patients with opisthorchiasis, clonorchiasis, and taeniasis were less than 10%. Although we could not verify that patients had active infections because of limitations inherent to claims data, including coding errors and the inability to review patients\u2019 charts, these data suggest a need for improved treatment of parasitic infections. Further research is needed to verify the results and identify potential clinical and public health consequences.<\/jats:p>","DOI":"10.4269\/ajtmh.22-0291","type":"journal-article","created":{"date-parts":[[2022,8,22]],"date-time":"2022-08-22T13:04:58Z","timestamp":1661173498000},"page":"780-784","source":"Crossref","is-referenced-by-count":2,"title":["Low Treatment Rates of Parasitic Diseases with Standard-of-Care Prescription Drugs in the United States, 2013\u20132019"],"prefix":"10.4269","volume":"107","author":[{"given":"Heesoo","family":"Joo","sequence":"first","affiliation":[{"name":"Division of Global Migration and Quarantine, Centers for Disease Control and Prevention, Atlanta, Georgia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian A.","family":"Maskery","sequence":"additional","affiliation":[{"name":"Division of Global Migration and Quarantine, Centers for Disease Control and Prevention, Atlanta, Georgia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan D.","family":"Alpern","sequence":"additional","affiliation":[{"name":"HealthPartners Institute, Bloomington, Minnesota;"},{"name":"Department of Medicine, University of Minnesota, Minneapolis, Minnesota;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca J.","family":"Chancey","sequence":"additional","affiliation":[{"name":"Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Weinberg","sequence":"additional","affiliation":[{"name":"Division of Global Migration and Quarantine, Centers for Disease Control and Prevention, Atlanta, Georgia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William M.","family":"Stauffer","sequence":"additional","affiliation":[{"name":"Division of Global Migration and Quarantine, Centers for Disease Control and Prevention, Atlanta, Georgia;"},{"name":"Department of Medicine, University of Minnesota, Minneapolis, Minnesota;"},{"name":"Center for Global Health and Social Responsibility, University of Minnesota, Minneapolis, Minnesota"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Am J Med","doi-asserted-by":"publisher","first-page":"545.e1","DOI":"10.1016\/j.amjmed.2006.05.072","article-title":"Maltreatment of Strongyloides infection: case series and worldwide physicians-in-training survey","volume":"120","year":"2007"},{"key":"b2","series-title":"Clin Infect Dis","first-page":"142","article-title":"Imported malaria: prospective analysis of problems in diagnosis and management","volume":"27","year":"1988"},{"key":"b3","series-title":"Mol Diagn Ther","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1007\/BF03256295","article-title":"Diagnosis of malaria: challenges for clinicians in endemic and non-endemic regions","volume":"12","year":"2008"},{"key":"b4","series-title":"Pediatrics","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1542\/peds.92.1.83","article-title":"Malaria in children in Chicago","volume":"92","year":"1993"},{"key":"b5","series-title":"Clin Pediatr (Phila)","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1177\/000992280604500210","article-title":"Hematuria in children due to schistosomiasis in a nonendemic setting","volume":"45","year":"2006"},{"key":"b6","series-title":"Travel Med Infect Dis","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.tmaid.2017.12.002","article-title":"Time delays in the diagnosis and treatment of malaria in non-endemic countries: a systematic review","volume":"21","year":"2018"},{"key":"b7","series-title":"Health Aff","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1377\/hlthaff.20.1.247","article-title":"Left out: immigrants\u2019 access to health care and insurance","volume":"20","year":"2001"},{"key":"b8","series-title":"J Commun Health","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1007\/s10900-009-9175-3","article-title":"Healthcare barriers of refugees post-resettlement","volume":"34","year":"2009"},{"key":"b9","series-title":"Ethn Health","first-page":"523","article-title":"Is health a right for all? 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