{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:31:15Z","timestamp":1768437075175,"version":"3.49.0"},"reference-count":21,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","license":[{"start":{"date-parts":[[2023,8,2]],"date-time":"2023-08-02T00:00:00Z","timestamp":1690934400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,2]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>It remains unclear whether a previous history of tropical infectious diseases and a second SARS-COV-2 infection may influence the likelihood of later symptoms. In this prospective cohort study, individuals infected with SARS-CoV-2 were followed up by telephone shortly after diagnosis of COVID-19 and again 12 months later. Poisson regression was used to identify the predictors of the highest number of symptoms in the post-COVID-19 syndrome. A total of 1,371 patients with COVID-19, with a mean age of 39.7 \u00b1 11.7 years and 50% female, were followed for 12 months. Reinfection was found in 32 (2.3%) participants, and 806 (58.8%) individuals reported a previous history of dengue, malaria, Zika, chikungunya, leprosy, and visceral leishmaniasis. Eight hundred seventy-seven (63.9%) participants reported late symptoms related to COVID-19. After adjusting for multiple factors, female sex, non-White race, number of acute-phase symptoms, body mass index, and reinfection were independent predictors of higher number of symptoms in post-COVID-19 syndrome. Female sex, non-White race, number of acute-phase symptoms, body mass index, and reinfection, but not previous endemic tropical diseases, were associated with long-term symptoms.<\/jats:p>","DOI":"10.4269\/ajtmh.22-0362","type":"journal-article","created":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T14:20:41Z","timestamp":1687789241000},"page":"466-470","source":"Crossref","is-referenced-by-count":8,"title":["Prevalence and Predictors of COVID-19 Long-Term Symptoms: A Cohort Study from the Amazon Basin"],"prefix":"10.4269","volume":"109","author":[{"given":"Kletey M.","family":"Silva","sequence":"first","affiliation":[{"name":"Federal University of Acre, Rio Branco, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dhayn C. A.","family":"Freitas","sequence":"additional","affiliation":[{"name":"Federal University of Acre, Rio Branco, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina S.","family":"Medeiros","sequence":"additional","affiliation":[{"name":"Federal University of Acre, Rio Branco, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"La\u00eds V. A.","family":"Miranda","sequence":"additional","affiliation":[{"name":"Federal University of Acre, Rio Branco, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica B. M.","family":"Carmo","sequence":"additional","affiliation":[{"name":"Federal University of Acre, Rio Branco, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta G.","family":"Silva","sequence":"additional","affiliation":[{"name":"Federal University of Acre, Rio Branco, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luana L.","family":"Becker","sequence":"additional","affiliation":[{"name":"Federal University of Acre, Rio Branco, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuel S.","family":"Abreu","sequence":"additional","affiliation":[{"name":"Federal University of Acre, Rio Branco, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo","family":"Buranello","sequence":"additional","affiliation":[{"name":"Federal University of Acre, Rio Branco, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria S. M.","family":"Souza","sequence":"additional","affiliation":[{"name":"Federal University of Acre, Rio Branco, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilson","family":"Nadruz","sequence":"additional","affiliation":[{"name":"University of Campinas, Campinas, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel M.","family":"Fernandes-Silva","sequence":"additional","affiliation":[{"name":"Federal University of Parana, Curitiba, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James H.","family":"Maguire","sequence":"additional","affiliation":[{"name":"Division of Infectious Disease, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, Massachusetts;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Toledo-Cornell","sequence":"additional","affiliation":[{"name":"Department of Medicine, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Odilson M.","family":"Silvestre","sequence":"additional","affiliation":[{"name":"Federal University of Acre, Rio Branco, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","year":"2022"},{"key":"b2","series-title":"PLoS One","first-page":"e0234765","article-title":"The prevalence of symptoms in 24,410 adults infected by the novel coronavirus (SARS-CoV-2; COVID-19): a systematic review and meta-analysis of 148 studies from 9 countries","volume":"15","author":"Grant","year":"2020"},{"key":"b3","series-title":"Clin Infect Dis","first-page":"e482","article-title":"Evolution of coronavirus disease 2019 (COVID-19) symptoms during the first 12 months after illness onset","volume":"75","author":"Wynberg","year":"2021"},{"key":"b4","series-title":"J Clin Med","first-page":"5913","article-title":"A systematic review of persistent symptoms and residual abnormal 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