{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T03:26:58Z","timestamp":1784172418041,"version":"3.55.0"},"reference-count":12,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,1]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>This report is on a 45-year-old male patient without underlying disease who presented with a <jats:italic>Burkholderia pseudomallei<\/jats:italic>\u2013caused keratoscleritis in his right eye. Slit-lamp examination revealed multiple, indistinct corneal infiltrations with subconjunctival\/scleral abscesses. Corneal tissue culture was positive for <jats:italic>B. pseudomallei<\/jats:italic> and confirmed by mass spectrometry. The patient was treated with fortified ceftazidime, fortified gentamicin eyedrops, and intravenous ceftazidime injection. Penetrating keratoplasty, including intracameral ceftazidime injections, was undertaken due to corneal lesion worsening. Scleral debridement with subconjunctival ceftazidime injections were undertaken due to the progression of the scleral abscess. After 2 months, the corneal and scleral lesions were inactive, and the systemic and topical antibiotics were tapered. This is the first case report of <jats:italic>B. pseudomallei<\/jats:italic>\u2013caused keratoscleritis with photography. The patient was seen in an endemic geographical area with multiple corneal infiltrations and subconjunctival\/scleral abscess. Systemic and topical antibiotics accompanied with surgery should be considered.<\/jats:p>","DOI":"10.4269\/ajtmh.22-0443","type":"journal-article","created":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T13:08:34Z","timestamp":1671455314000},"page":"293-295","source":"Crossref","is-referenced-by-count":4,"title":["Case Report: Burkholderia pseudomallei\u2013Caused Sclerokeratitis"],"prefix":"10.4269","volume":"108","author":[{"given":"Onsiri","family":"Thanathanee","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Korawin","family":"Charoensuk","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuwarat","family":"Uthairat","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suparat","family":"Laohapitakvorn","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Orapin","family":"Anutarapongpan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olan","family":"Suwan-apichon","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2795","reference":[{"key":"b1","series-title":"Clin Microbiol Rev","first-page":"e00006","article-title":"Human melioidosis","volume":"33","author":"Gassiep","year":"2020"},{"key":"b2","series-title":"Aust J Gen Pract","first-page":"327","article-title":"Melioidosis: an updated review","volume":"48","author":"Chakravorty","year":"2019"},{"key":"b3","series-title":"Clin Med (Lond)","first-page":"6","article-title":"Melioidosis: clinical aspects","volume":"22","author":"Karunanayake","year":"2022"},{"key":"b4","series-title":"J Ophthalmic Inflamm Infect","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s12348-018-0147-6","article-title":"Ocular involvement in melioidosis: a 23-year retrospective review","volume":"8","author":"Yaisawang","year":"2018"},{"key":"b5","series-title":"Rev Infect 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