{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T18:40:53Z","timestamp":1776883253918,"version":"3.51.2"},"reference-count":27,"publisher":"American Society of Tropical Medicine and Hygiene","issue":"3","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,1]]},"abstract":"<jats:title>ABSTRACT.<\/jats:title>\n<jats:p>Travelers to Chagas disease endemic regions of Latin America may be at risk for <jats:italic>Trypanosoma cruzi<\/jats:italic> infection. We report a 67-year-old woman who screened positive for <jats:italic>T. cruzi<\/jats:italic> infection while donating blood. The patient had a history of an unusual febrile illness and marked swelling of the face sustained at age 10 after camping in northern Mexico that led to a 3-week hospitalization without a diagnosis. More than 4 decades later, rapid diagnostic tests and commercial and confirmatory serology for Chagas disease were all positive for <jats:italic>T. cruzi<\/jats:italic> infection. On evaluation, the patient described a progressive chronic cough, gastroesophageal reflux, and dysphagia for &gt; 10 years. There was no evidence of any cardiac complications. However, esophageal manometry demonstrated significant dysmotility, with 90% of swallows being ineffective with evidence of esophageal pressurization and retrograde peristalsis in several swallows, suggesting early autonomic disruption due to Chagas disease esophagopathy. In this report, we highlight the importance of travel-related Chagas disease among travelers to endemic regions and the need to further identify potential risks of transmission among this at-risk population.<\/jats:p>","DOI":"10.4269\/ajtmh.22-0461","type":"journal-article","created":{"date-parts":[[2023,1,16]],"date-time":"2023-01-16T14:05:13Z","timestamp":1673877913000},"page":"543-547","source":"Crossref","is-referenced-by-count":3,"title":["Case Report: Chagas Disease in a Traveler Who Developed Esophageal Involvement Decades after Acute Infection"],"prefix":"10.4269","volume":"108","author":[{"given":"Norman L.","family":"Beatty","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases and Global Medicine, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida;"},{"name":"Emerging Pathogens Institute, University of Florida, Gainesville, Florida;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo F.","family":"Alcala","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Global Medicine, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nelson A.","family":"Luque","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases and Global Medicine, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Radetic","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology & Nutrition, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priti","family":"Joshi-Guske","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology & Nutrition, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eyad","family":"Alakrad","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology & Nutrition, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin J.","family":"Forsyth","sequence":"additional","affiliation":[{"name":"Drugs for Neglected Diseases Initiative, New York, New York;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davidson H.","family":"Hamer","sequence":"additional","affiliation":[{"name":"Department of Global Health, Boston University School of Public Health, Boston, Massachusetts;"},{"name":"Section of Infectious Diseases, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts;"},{"name":"Center for Emerging Infectious Disease Research and Policy, Boston University, Boston, Massachusetts;"},{"name":"National Emerging Infectious Disease Laboratory, Boston University, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2795","reference":[{"key":"b1","year":"2022"},{"key":"b2","year":"2020"},{"key":"b3","series-title":"Am J Trop Med Hyg","first-page":"1038","article-title":"Acute Chagas disease in a returning traveler","volume":"87","author":"Carter","year":"2012"},{"key":"b4","series-title":"The GeoSentinel Newsletter: Information for Action. 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